Lactams
Medchemexpress LLC Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride | 2983037-00-7 | >98.0% | 586.03 | 25 MG
Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. It integrates a thalidomide-based cereblon ligand with a linker, making it suitable for applications in PROTAC technology. This compound is intended for research purposes only and is not for sale to patients.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates thalidomide-based cereblon ligand
- Utilizes a linker for PROTAC technology applications
- Suitable for research use
Chemscene ChemScene | Thalidomide 5-fluoride | 5G | CS-0127616 | 0.98 | 835616-61-0| MFCD30188075 | 276.22
ChemScene | Thalidomide 5-fluoride | 5G | CS-0127616 | 0.98 | 835616-61-0| MFCD30188075 | 276.22
Medchemexpress LLC Thalidomide-4-O-C7-NH2 hydrochloride | 99.8% | 423.89 g/mol | C20H26ClN3O5 | 5 MG
Thalidomide-4-O-C7-NH2 hydrochloride is a thalidomide-derived cereblon ligand-linker conjugate used as an E3 ligase ligand in PROTAC development and CRBN recruitment studies.
- High chemical purity: 99.8%.
- Hydrochloride salt form for improved stability and solubility.
- Molecular formula C20H26ClN3O5; molecular weight 423.89 g/mol.
- Optimized for use as an E3 ligase ligand in biochemical and cell-based assays.
- Supplied in small research quantities suitable for synthesis and assay development.
Medchemexpress LLC 2,6-piperidinedione, 3-(1,3-dihydro-5-iodo-1-oxo-2H-isoindol-2-yl) | 2291364-01-5 | MFCD32853043 | 98.0% | 370.14 | C13H11IN2O3 | 50 MG
Deoxy-thalidomide-5-iodine is an iodinated thalidomide analog intended for chemical biology and PROTAC applications; it functions as a cereblon-binding ligand for E3 ligase recruitment and is supplied with analytical data confirming identity and high purity.
- Iodinated thalidomide analog useful for PROTAC research.
- Binds cereblon to enable E3 ligase recruitment.
- High purity: 98.0% by NMR.
- Molecular weight 370.14; formula C13H11IN2O3.
- Appearance: blue to blue-green solid.
- Store protected from light at 4°C; in solvent keep at -80°C (6 months) or -20°C (1 month).
- Supplied in small research quantities (50 mg).
Medchemexpress LLC Thalidomide 5-fluoride | 835616-61-0 | MFCD30188075 | 100.0% | 276.22 g/mol | C13H9FN2O4 | 10 G
Thalidomide 5-fluoride is a thalidomide-derived cereblon ligand used as a building block in PROTAC degraders and other bifunctional molecules. It is supplied as a high-purity solid reagent intended for research and chemical biology applications.
- High purity solid (99.96%).
- Molecular weight 276.22 g/mol.
- Molecular formula C13H9FN2O4.
- Available in laboratory pack sizes, including 10 G.
- Storage: powder at -20°C for long-term, 4°C for shorter term; in solvent store at -80°C.
Apexbio Technology LLC Brucine 20mg
N1490 is a small-molecule inhibitor designed for biomedical research It exerts its effects by selectively targeting and modulating specific intracellular signaling pathways implicated in disease progression N1490 has been explored in cellular assays for its ability to interfere with relevant molecular interactions resulting in altered downstream signaling events This compound serves as a valuable tool for investigating cellular mechanisms regulated by these pathways and may facilitate the discovery of novel therapeutic strategies in areas such as oncology immunology or metabolic research
Medchemexpress LLC Thalidomide-5-O-C10-NH2 hydrochloride | 99.4% | 465.97 g/mol | C23H32ClN3O5 | 10 MG
Thalidomide-5-O-C10-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand supplied as the hydrochloride salt for chemical biology research. It is used to recruit the CRBN E3 ubiquitin ligase in PROTAC and conjugate applications to enable targeted protein ubiquitination and degradation. Molecular formula C23H32ClN3O5; molecular weight 465.97 g/mol.
- Used as a cereblon-binding ligand for PROTAC and conjugate design.
- Supplied as the hydrochloride salt for improved handling and stability.
- High purity suitable for research applications.
- Available in small research pack sizes for synthesis and screening.
- Provides a chemical handle designed for linker attachment to target ligands.