Lactams
eMolecules 17557-84-5 | 3-Azetidinone hydrochloride | Combi-Blocks | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 267164568
3-Azetidinone hydrochloride | Combi-Blocks | 17557-84-5 | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 267164568
Medchemexpress LLC Aztreonam | 78110-38-0 | 99.6% | 1 ML
Aztreonam is a synthetic monocyclic beta-lactam antibiotic with a high affinity for penicillin-binding protein 3 (PBP-3). It was approved by the U.S. Food and Drug Administration in 1986. This antibiotic is resistant to some beta-lactamases but can be inactivated by extended-spectrum beta-lactamases. It shows no useful activity against gram-positive or anaerobic microorganisms. Aztreonam inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking. It has a mild affinity for PBP-1a and is largely ineffective against gram-positive and anaerobic bacteria due to poor binding to their penicillin-binding proteins. Aztreonam is bactericidal, though less so than some cephalosporins.
- Synthetic monocyclic beta-lactam antibiotic
- High affinity for penicillin-binding protein 3 (PBP-3)
- Resistant to some beta-lactamases
- Inhibits mucopeptide synthesis in the bacterial cell wall
- Bactericidal
eMolecules Thalidomide-5-(PEG4-amine) | Broadpharm |520.539 | C24H32N4O9 | 0.000 | NCCOCCOCCOCCOCCNC(=O)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 | 100mg | 713699642
Thalidomide-5-(PEG4-amine) | Broadpharm |520.539 | C24H32N4O9 | 0.000 | NCCOCCOCCOCCOCCNC(=O)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 | 100mg | 713699642
Medchemexpress LLC Thalidomide-O-PEG4-azide | 2380318-57-8 | 98.0% | C23H29N5O9 | 100 MG
Thalidomide-O-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the thalidomide based cereblon ligand and a linker used in PROTAC technology. It is a click chemistry reagent, containing an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates thalidomide based cereblon ligand
- Used in PROTAC technology
- Click chemistry reagent containing an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC)
- Molecular weight of 519.50
- Appears as a colorless to light yellow oil