Lactams
Aztreonam 98.0+%, TCI America™
CAS: 78110-38-0 Molecular Formula: C13H17N5O8S2 Molecular Weight (g/mol): 435.426 MDL Number: MFCD00072145 InChI Key: WZPBZJONDBGPKJ-PSGLRMFWSA-N Synonym: trans-2-1-2-aminothiazol-4-yl-2-2-methyl-4-oxo-1-sulphoazetidin-3-yl amino-2-oxoethylidene amino oxy-2-methylpropionic acid,2-1-2-amino-4-thiazolyl-2-2r-2alpha-methyl-4-oxo-1-sulfo-3beta-azetidinyl amino-2-oxoethylidene amino oxy-2-methylpropanoic acid PubChem CID: 56842327 IUPAC Name: 2-[(E)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2R,3R)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid SMILES: CC1C(C(=O)N1S(=O)(=O)O)NC(=O)C(=NOC(C)(C)C(=O)O)C2=CSC(=N2)N
Apexbio Technology LLC Aztreonam 78110-38-0 100mg
Aztreonam (CAS 78110-38-0) is a synthetic monocyclic -lactam antibiotic targeting penicillin-binding protein 3 (PBP3) It is designed to bind to PBP3 thereby disrupting bacterial cell wall synthesis and inhibiting bacterial growth Aztreonam exerts its biological activity primarily through inhibition of cell wall synthesis in aerobic Gram-negative bacteria In in vitro studies Aztreonam demonstrates selective antibacterial activity with reported IC50 values ranging from 0 05 8 g/mL against sensitive Gram-negative bacterial strains depending on species and experimental conditions Based on these pharmacological properties Aztreonam holds research potential in studies of bacterial resistance mechanisms -lactamase susceptibility profiles and evaluation of antibiotic permeability
Medchemexpress LLC Aztreonam | 78110-38-0 | 99.6% | 1 ML
Aztreonam is a synthetic monocyclic beta-lactam antibiotic with a high affinity for penicillin-binding protein 3 (PBP-3). It was approved by the U.S. Food and Drug Administration in 1986. This antibiotic is resistant to some beta-lactamases but can be inactivated by extended-spectrum beta-lactamases. It shows no useful activity against gram-positive or anaerobic microorganisms. Aztreonam inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking. It has a mild affinity for PBP-1a and is largely ineffective against gram-positive and anaerobic bacteria due to poor binding to their penicillin-binding proteins. Aztreonam is bactericidal, though less so than some cephalosporins.
- Synthetic monocyclic beta-lactam antibiotic
- High affinity for penicillin-binding protein 3 (PBP-3)
- Resistant to some beta-lactamases
- Inhibits mucopeptide synthesis in the bacterial cell wall
- Bactericidal
Medchemexpress LLC Aztreonam | 78110-38-0 | 99.6% | 200 MG
Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic that exhibits a very high affinity for penicillin-binding protein 3 (PBP-3). It functions by inhibiting mucopeptide synthesis within the bacterial cell wall, thereby preventing peptidoglycan crosslinking. While resistant to some beta-lactamases, it is inactivated by extended-spectrum beta-lactamases. Aztreonam demonstrates no useful activity against gram-positive or anaerobic microorganisms.
- Inhibits mucopeptide synthesis in bacterial cell walls
- Blocks peptidoglycan crosslinking
- High affinity for penicillin-binding protein 3 (PBP-3)
- Resistant to certain beta-lactamases
- Bactericidal properties
Medchemexpress LLC Aztreonam (Standard) | 78110-38-0 | 99.6% | 5 MG
Aztreonam (Standard) is the analytical standard of Aztreonam, intended for research and analytical applications. This synthetic monocyclic beta-lactam antibiotic has a very high affinity for penicillin-binding protein 3 (PBP-3).
- Reference standard supplied assay
- Used in qualitative research experiments
- Used in quantitative research experiments
- Used in methodological research experiments
- Suitable for HPLC
- Suitable for GC
- Suitable for MS
Medchemexpress LLC Aztreonam (Standard) | 78110-38-0 | 99.6% | 50 MG
Aztreonam (Standard) is an analytical standard intended for research and analytical applications. It is a synthetic monocyclic beta-lactam antibiotic, also known as SQ-26,776, which demonstrates a high affinity for penicillin-binding protein 3 (PBP-3). This product is suitable for qualitative, quantitative, and methodological research experiments, including HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Synthetic monocyclic beta-lactam antibiotic
- High affinity for penicillin-binding protein 3 (PBP-3)
- Suitable for HPLC, GC, and MS research experiments
Medchemexpress LLC Aztreonam (Standard) | 78110-38-0 | 99.6% | 100 MG
Aztreonam (Standard) is an analytical reference standard. It is a synthetic monocyclic beta-lactam antibiotic exhibiting high affinity for penicillin-binding protein 3 (PBP-3), making it suitable for various research and analytical applications.
- Analytical standard grade
- Reference standard for assays
- Suitable for qualitative research
- Suitable for quantitative research
- Suitable for methodological research
- Commonly used in HPLC
- Commonly used in GC
- Commonly used in MS
Apexbio Technology LLC Aztreonam 78110-38-0 10mM (in 1mL DMSO)
Aztreonam (CAS 78110-38-0) is a synthetic monocyclic -lactam antibiotic targeting penicillin-binding protein 3 (PBP3) It is designed to bind to PBP3 thereby disrupting bacterial cell wall synthesis and inhibiting bacterial growth Aztreonam exerts its biological activity primarily through inhibition of cell wall synthesis in aerobic Gram-negative bacteria In in vitro studies Aztreonam demonstrates selective antibacterial activity with reported IC50 values ranging from 0 05 8 g/mL against sensitive Gram-negative bacterial strains depending on species and experimental conditions Based on these pharmacological properties Aztreonam holds research potential in studies of bacterial resistance mechanisms -lactamase susceptibility profiles and evaluation of antibiotic permeability
Medchemexpress LLC Aztreonam (Standard) | 78110-38-0 | 72145 | 99.6% | 25 MG
Aztreonam (Standard) is an analytical standard and synthetic monocyclic beta-lactam antibiotic. It is intended for research and analytical applications, serving as a reference standard for assays.
- Used in qualitative, quantitative, and methodological research experiments
- Utilized with techniques such as HPLC, GC, and MS
- Possesses a very high affinity for penicillin-binding protein 3 (PBP-3)
Medchemexpress LLC Aztreonam | 78110-38-0 | MFCD00072145 | 99.6% | 435.43 | C13H17N5O8S2 | 10 MG
Aztreonam (standard) is an analytical reference material containing the monobactam antibiotic aztreonam. Provided at high purity, it is intended for analytical testing, assay calibration, method validation, and quality control in pharmaceutical and biochemical laboratories.
- Analytical reference standard for aztreonam.
- High purity suitable for assay and quality control work.
- Available in small precision pack sizes for analytical use.
- Reported molecular weight 435.43 and formula C13H17N5O8S2.
- Includes CAS number 78110-38-0 for unambiguous identification.