Lactams
Tazobactam sodium
CAS: 89785-84-2 Molecular Formula: C10H12N4NaO5S Molecular Weight (g/mol): 323.279 MDL Number: MFCD00917472 InChI Key: ZUNWFYFXHGWFRA-QVUDESDKSA-N Synonym: tazobactam sodium salt PubChem CID: 66636300 IUPAC Name: (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4$l^{6}-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;sodium SMILES: CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3.[Na]
Tazobactam Sodium, G-Biosciences
Molecular Weight (g/mol): 322.27 g/mol
Sulbactam Sodium, G-Biosciences
Molecular Weight (g/mol): 255.22 g/mol
Selleck Chemical LLC Sulbactam sodium S2551-50mg
Sulbactam sodium (Unasyn CP-45899-2) is an irreversible -lactamase inhibitor
Selleck Chemical LLC Tazobactam Sodium-E0167-25MG
Tazobactam (Tazobactam acid Tazobactamum) Sodium is a beta-lactamase inhibitor that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms
Selleck Chemical LLC Tazobactam Sodium-E0167-5MG
Tazobactam (Tazobactam acid Tazobactamum) Sodium is a beta-lactamase inhibitor that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms
Apexbio Technology LLC Tazobactam (sodium salt) 89785-84-2 250mg
Tazobactam sodium salt (CAS 89785-84-2) is a small-molecule inhibitor targeting -lactamases It is designed to irreversibly bind to -lactamases thereby preventing the enzyme-mediated hydrolysis of -lactam antibiotics Tazobactam sodium salt exerts its biological activity primarily through -lactamase inhibition In microbiological assays tazobactam demonstrates intrinsic antibacterial activity against several Acinetobacter strains typically with MIC values of 8 mg/L (range 2 32 mg/L) Based on these pharmacological properties tazobactam sodium salt holds research potential in microbiological assessments and efficacy evaluations of -lactam antibiotic combinations
Medchemexpress LLC Sulbactam sodium | 69388-84-7 | 99.4% | 5 MG
Sulbactam sodium is the analytical standard of Sulbactam (sodium) and is intended for research and analytical applications. It is a competitive, irreversible beta-lactamase inhibitor, demonstrating antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex. This compound is of analytical standard grade and is commonly used as a reference standard in research experiments.
- Intended for research and analytical applications
- Competitive, irreversible beta-lactamase inhibitor
- Exhibits antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex
- Used as a reference standard in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Apexbio Technology LLC Sulbactam sodium,100mg CAS# 69388-84-7
Sulbactam sodium. Other sizes are also available. Please inqury us for quote.
Apexbio Technology LLC Tazobactam (sodium salt) 89785-84-2 1g
Tazobactam sodium salt (CAS 89785-84-2) is a small-molecule inhibitor targeting -lactamases It is designed to irreversibly bind to -lactamases thereby preventing the enzyme-mediated hydrolysis of -lactam antibiotics Tazobactam sodium salt exerts its biological activity primarily through -lactamase inhibition In microbiological assays tazobactam demonstrates intrinsic antibacterial activity against several Acinetobacter strains typically with MIC values of 8 mg/L (range 2 32 mg/L) Based on these pharmacological properties tazobactam sodium salt holds research potential in microbiological assessments and efficacy evaluations of -lactam antibiotic combinations
Apexbio Technology LLC Tazobactam (sodium salt) 89785-84-2 500mg
Tazobactam sodium salt (CAS 89785-84-2) is a small-molecule inhibitor targeting -lactamases It is designed to irreversibly bind to -lactamases thereby preventing the enzyme-mediated hydrolysis of -lactam antibiotics Tazobactam sodium salt exerts its biological activity primarily through -lactamase inhibition In microbiological assays tazobactam demonstrates intrinsic antibacterial activity against several Acinetobacter strains typically with MIC values of 8 mg/L (range 2 32 mg/L) Based on these pharmacological properties tazobactam sodium salt holds research potential in microbiological assessments and efficacy evaluations of -lactam antibiotic combinations
Medchemexpress LLC Sulbactam sodium | 69388-84-7 | 99.4% | 50 MG
Sulbactam sodium (Standard) is an analytical standard intended for research and analytical applications. It functions as a competitive, irreversible beta-lactamase inhibitor, demonstrating antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex.
- Used as a reference standard for assays
- Competitive, irreversible beta-lactamase inhibitor
- Shows antimicrobial activity against multidrug-resistant acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex
- Utilized in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Medchemexpress LLC Sulbactam sodium | 69388-84-7 | 99.41% | 100 MG
Sulbactam sodium is an analytical standard intended for research and analytical applications. It functions as a competitive, irreversible beta-lactamase inhibitor and demonstrates antimicrobial activity against multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex. This compound serves as a reference for assays and is commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Competitive, irreversible beta-lactamase inhibitor
- Antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex
- Used in HPLC, GC, and MS experiments
Medchemexpress LLC Tazobactam sodium | 89785-84-2 | 99.7% | 322.27 | 100 MG
Tazobactam sodium is an antibiotic belonging to the beta-lactamase inhibitor class. It is combined with Ceftolozane to enhance the activity of ceftolozane against various ESBL-producing Enterobacteriaceae and some *Bacteroides spp.*. It is intended for research use only and not for sale to patients. In vitro studies show that Tazobactam sodium (0.045 mg/mL Piperacillin/Tazobactam, 3 days) can induce oxidative stress and mitochondrial damage, leading to apoptosis in HK-2 cells when used with Piperacillin. In vivo, Tazobactam sodium (300-500 mg/kg of Piperacillin/Tazobactam, iv, single dose) has been observed to cause direct nephrotoxicity, including tubular damage and mitochondrial structure alteration, in C57BL/6 mouse models.
- Beta-lactamase inhibitor
- Extends activity of ceftolozane against ESBL-producing Enterobacteriaceae and *Bacteroides spp*.
Apexbio Technology LLC Sulbactam sodium 69388-84-7 10mM (in 1mL H2O)
Sulbactam sodium is a competitive and irreversible inhibitor targeting -lactamase enzymes It functions predominantly through binding the active site of -lactamases thereby obstructing these enzymes from hydrolyzing -lactam antibiotics Widely employed in biomedical research Sulbactam sodium is utilized for evaluating bacterial resistance mechanisms characterizing susceptibility profiles of -lactamase-expressing clinical isolates and examining synergistic therapeutic combinations Moreover Sulbactam sodium itself exhibits antimicrobial activity notably against Acinetobacter species clinically resistant to common antibiotics In antibacterial assays against certain -lactamase-producing bacterial strains Sulbactam sodium typically demonstrates inhibitory effects at IC50 values ranging approximately from 5 to 25 g/mL depending upon specific experimental conditions
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