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Organic heterocyclic compounds that consist of a cyclic carboximidic acid characterized by a carbon-nitrogen double bond within the ring; they are tautomeric with the lactams.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
7030B-C5 is a small-molecule PCSK9 inhibitor intended for preclinical research. It shows in vitro activity (IC50 = 1.61 μM) and has been reported to reduce plasma cholesterol and triglyceride levels in vivo. The compound is identified by CAS No. 370871-42-4 and is supplied at high purity for laboratory studies.
Small-molecule PCSK9 inhibitor with reported IC50 of 1.61 μM.
Demonstrated in vivo activity reducing plasma cholesterol and triglyceride levels.
High purity (99.78%), suitable for preclinical studies.
Characterized molecular weight 359.38 g/mol and formula C17H21N5O4.
Supplied as a 10 mg quantity for laboratory use.
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Cycloheximide cryst. pure Glutarimide antibiotic isolated from Streptomyces griseus; active against fungi and yeasts, but not against bacteria. Inhibits eukaryotic protein synthesis by blocking the translocation step in the elongation cycle (1,3,8). Blocks tra
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An inhibitor of protein synthesis in eukaryotes (IC50 = 5-50 μM) that functions by interfering with translational elongation; can either induce or inhibit apoptosis depending on cell type
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
An inhibitor of protein synthesis in eukaryotes (IC50 = 5-50 μM) that functions by interfering with translational elongation; can either induce or inhibit apoptosis depending on cell type
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Also available in 200 mg and bulk. Please contact Fisher for quotes. Cycloheximide (Naramycin A) is a natural product that reversibly inhibits translation elongation, is an antimitotic compound, and is an inhibitor of DNA and protein synthesis.
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A cell-permeable fungal toxin that is approximately 10 times more potent than cytochalasin B (Cat. No. 250233) in inhibiting actin filament function. Does not inhibit monosaccharide transport across cell membranes. Inhibits cytoplasmic division by blocking the formation of contractile microfilaments at 10 181M. Inactivates low conductance K channels. Also modulates CD4 cross-linking in T lymphocytes and increases intracellular Ca2 levels. Cytochalasin D also exhibits antibiotic and anti-tumor properties.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More