Lactims
Cycloheximide, from Microbial, MP Biomedicals™
CAS: 66-81-9 Molecular Formula: C15H23NO4 Molecular Weight (g/mol): 281.35 MDL Number: MFCD00082346 InChI Key: YPHMISFOHDHNIV-QTEFRXOUNA-N Synonym: cycloheximide,actidione,cycloheximide,naramycin a,kaken,actidion,actidone,hizarocin,naramycin,neocycloheximide PubChem CID: 6197 ChEBI: CHEBI:27641 IUPAC Name: 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione SMILES: [H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1
DL-Aminoglutethimide, 99%
CAS: 125-84-8 Molecular Formula: C13H16N2O2 Molecular Weight (g/mol): 232.283 MDL Number: MFCD00010122 InChI Key: ROBVIMPUHSLWNV-UHFFFAOYSA-N Synonym: aminoglutethimide,dl-aminoglutethimide,cytadren,orimeten,p-aminoglutethimide,elipten,3-4-aminophenyl-3-ethylpiperidine-2,6-dione,aminoglutetimida,3-4-aminophenyl-3-ethyl-2,6-piperidinedione,aminoglutethimidum PubChem CID: 2145 ChEBI: CHEBI:2654 IUPAC Name: 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione SMILES: CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N
Thermo Scientific Chemicals Cycloheximide, 95%
CAS: 66-81-9 Molecular Formula: C15H23NO4 Molecular Weight (g/mol): 281.35 MDL Number: MFCD00082346 InChI Key: YPHMISFOHDHNIV-QTEFRXOUNA-N Synonym: cycloheximide,actidione,cycloheximide,naramycin a,kaken,actidion,actidone,hizarocin,naramycin,neocycloheximide PubChem CID: 6197 ChEBI: CHEBI:27641 IUPAC Name: 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione SMILES: [H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1
2-Azetidinone, 98%
CAS: 930-21-2 Molecular Formula: C3H5NO Molecular Weight (g/mol): 71.08 MDL Number: MFCD00013328 InChI Key: MNFORVFSTILPAW-UHFFFAOYSA-N Synonym: 2-azetidinone,beta-propiolactam,azetidinone,propiolactam,azetan-2-one,beta-lactam,2-azetdinone,azetidine-2-one,acmc-209xab PubChem CID: 136721 ChEBI: CHEBI:327119 IUPAC Name: azetidin-2-one SMILES: C1CNC1=O
Medchemexpress LLC Complement C5-IN-1 | 2365402-67-9 | 99.1% | 1 ML
Complement C5-IN-1 is a selective allosteric inhibitor of complement component protein C5. It prevents C5 from being cleaved by C5 convertase, which inhibits the cleavage of C5 into C5a and C5b, thus blocking the formation of the membrane attack complex (MAC).
- Selective allosteric inhibitor of complement component protein C5
- Prevents C5 from being cleaved by C5 convertase
- Inhibits the cleavage of C5 into C5a and C5b
- Blocks the formation of the membrane attack complex (MAC)
- Exhibits an IC50 of 0.77 μM in 50% human whole blood
- Exhibits an IC50 of 5 nM in 2% human serum to block MAC deposition induced by zymosan
- Useful for studying diseases associated with complement overactivation, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS)
TARGETMOL CHEMICALS INC COMPLEMENT C5-IN-1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5). purity: 99%
Gold Biotechnology Inc Cycloheximide 1 g
Cycloheximide is a protein synthesis inhibitor in eukaryotic cells It prevents ribosomal mRNA translocation during protein translation Cycloheximide has a variety of applications It can be used to study cellular processes and to determine the half-life of a protein using western blotting techniques of protein cell lysate It has been used to select for CHX-resistant strains of yeast and fungi It also displays neuroprotective properties Additionally Cycloheximide has been used to inhibit yeast growth at concentrations of 200 M It has been used to promote production of ethylene in leaves and fruit
AG Scientific Inc Cycloheximide 1 G
Cycloheximide is an antibiotic produced by Streptomyces sp. that activates against yeasts and fungi. It inhibits protein synthesis thru DNA translation arrest in eukaryotes. Cycloheximide also inhibits chain initiation and chain elongation by acting on 60S subunits of eukaryote ribosome.
Alkali Scientific Cycloheximide, 1 G
Cycloheximide is a protein synthesis inhibitor widely used in microbiology and cell biology laboratories as an antifungal agent. It functions by blocking the translocation step in eukaryotic ribosomes, effectively preventing protein synthesis in fungi and other eukaryotic organisms. This selective inhibition makes it useful in culture media where suppression of fungal growth is required while allowing bacterial growth to proceed. Cycloheximide is commonly incorporated into selective agar formulations and research protocols to control contamination by molds and yeasts. It is also used in molecular biology studies to investigate protein synthesis mechanisms and cellular responses to translational inhibition in experimental systems.
Medchemexpress LLC 2-Pyrimidinamine, 4-[4-(1H-imidazol-1-yl)phenyl]-N-2-propyn-1-yl- | 2234272-10-5 | 98.1% | 50 MG
AP-C5 is a selective inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 7.2. It is used for the research of diarrheal disease. This compound is also a click chemistry reagent containing an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that contain Azide groups.
- Potent inhibition of cGMP-dependent cGKII-mediated protein phosphorylation
- Effective inhibition of cGMP-dependent, CFTR-mediated anion secretion in intestinal tissue
- Potentiates cAMP signaling through PDE inhibition
- Partially blocks heat-stable toxin (STa)-mediated short-circuit current (Isc) response in mouse ileum
- Click chemistry reagent with an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Medchemexpress LLC 2-Pyrimidinamine, 4-[4-(1H-imidazol-1-yl)phenyl]-N-2-propyn-1-yl- | 2234272-10-5 | 98.1% | 25 MG
AP-C5 is a selective inhibitor of cGMP-dependent protein kinase II (cGKII) with a pIC50 of 7.2. It can be used for research on diarrheal disease and also functions as a click chemistry reagent containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Selective inhibitor of cGMP-dependent protein kinase II (cGKII)
- pIC50 of 7.2 for cGKII
- Useful for diarrheal disease research
- Click chemistry reagent with an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Potentiates cAMP signaling by PDE inhibition
- Partially blocks heat-stable toxin (STa)-mediated short-circuit current (Isc) response in mouse ileum
Sigma Aldrich Fine Chemicals Biosciences Cycloheximide, 66-81-9, MFCD00082346, 1 g
Empirical Formula (Hill Notation): C15H23NO4, Molecular Weight: 281.35, Synonym: 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, Actidione, Naramycin A, from microbial, ≥94% (TLC). In yeast strains, cycloheximide has been used as a protein synthesis inhibitor in the cycloheximide chase experiment. It has been used to inhibit translation in mammalian cells. It has been used to suppress fungal growth.
![Medchemexpress LLC 4-[4-(1H-Imidazol-1-yl)phenyl]-N-2-propyn-1-yl-2-pyrimidinamine | 2234272-10-5 | 98.1% | C16H13N5 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000258861.png-250.jpg)
Medchemexpress LLC 4-[4-(1H-Imidazol-1-yl)phenyl]-N-2-propyn-1-yl-2-pyrimidinamine | 2234272-10-5 | 98.1% | C16H13N5 | 10MG
AP-C5 is a selective small-molecule inhibitor of cGMP-dependent protein kinase II (cGKII) used in cellular and biochemical research, including studies of diarrheal disease. It also contains an alkyne functional group that enables copper-catalyzed azide-alkyne cycloaddition (click chemistry) for probe conjugation.
- Selective cGKII inhibition suitable for biochemical and cellular assays.
- Click-chemistry compatible alkyne for facile probe conjugation.
- High purity (>98%) for consistent experimental performance.
- Solid, light yellow to light brown physical form for straightforward handling.
- Stable when stored under recommended conditions for long-term use.
- Good solubility in DMSO for preparation of screening solutions.
Medchemexpress LLC Pomalidomide-CO-C5-Br | 2227423-38-1 | 450.28 | 100 MG
Pomalidomide-CO-C5-Br (Compound 6b) is a conjugated compound of the E3 ligand Pomalidomide and a linker. It can be used to synthesize highly effective PROTAC molecules targeting ADC. It is intended for research use only and not for sale to patients.
- Conjugated compound of E3 ligand Pomalidomide and linker.
- Used to synthesize PROTAC molecules.
- Targets ADCs.
- For research use only.
Medchemexpress LLC 10-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl)-4,7,13,16-tetraoxa-10-azanonadecanedioic acid | 3026691-12-0 | 98.0% | 530.57 g·mol-1 | C24H38N2O11 | 50mg
Mal-C5-N-bis(PEG2-C2-acid) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]