Lactones
Medchemexpress LLC Fc gamma RIII/CD16 100ug | 100ug
The Fc RIIIA/CD16a protein is a receptor for IgG and is optimally activated upon binding of aggregated antigen-IgG complexes inducing antibody-dependent cellular cytotoxicity (ADCC) It mediates IgG effector function on natural killer cells limiting viral load Fc gamma RIII/CD16 Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived Fc gamma RIII/CD16 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Gamma-secretase modulator 6 | 1255700-88-9 | 99.7% | 10 MG
Gamma-secretase modulator 6 is a high-purity research compound that modulates gamma-secretase activity and reduces Aβ42 secretion in cellular models (pIC50 8.1). It is provided as a solid or as a DMSO solution for preclinical biochemical and cellular research into Alzheimer's disease mechanisms.
- Inhibits Aβ42 secretion (pIC50 8.1).
- High purity suitable for research (99.68%).
- Available as solid and as a 10 mM DMSO solution.
- Molecular formula C25H26N6O2, molecular weight 442.51.
- Intended for preclinical and biochemical studies of amyloid processing.
eMolecules 1159598-33-0 | (S)-4-Methyl-2-(hydroxymethyl)morpholine | MFCD16294695 | 1g
Medchem Express | NAS-181 (dimesylate) | 5mg | 752822538 | HY-103156 | 1217474-40-2 | MFCD06798366 | 538.630 | C21H34N2O10S2
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eMolecules Building Block Tool
Medchemexpress LLC SIRP gamma Cynomolg 10ug | 10ug
SIRP gamma Protein a member of signal-regulatory protein (SIRP) family is the only SIRP detected on T cells and activated NK cells SIRP gamma can bind CD47 providing T cells and NK cells with a cell surface molecule capable of interacting with CD47 SIRP gamma-CD47 interaction mediates strong cell-cell adhesion and supports T cell-APC contact enhancing antigen presentation and consequent T-cell proliferation and cytokine secretion SIRP gamma Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived SIRP gamma protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC gamma-secretase modulator 6 | 1255700-88-9 | 99.7% | 442.51 | 5 MG
gamma-secretase modulator 6 is a gamma-secretase modulator that inhibits Aβ42 secretion in HEK cell lines stably expressing APP (Aβ amyloid precursor protein) with a pIC50 of 8.1. It can be used for Alzheimer's disease research.
- Inhibits Aβ42 secretion in HEK cell line stably expressing APP (Aβ amyloid precursor protein) (pIC50: 8.1)
- Can be used for research of Alzheimer's disease
- Appearance: solid
- Color: light yellow to yellow
C[C@@H]1CO | 1g | 233627353](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502171786.JPG-250.jpg)
eMolecules 1279038-50-4 | (2R,4R)-1-BOC-2-HYDROXYMETHYL-4-AMINOPYRROLIDINE HYDROCHLORIDE | AstaTech | MFCD11101163 | 252.740 | C10H21ClN2O3 | 95.000 | Cl.CC(C)(C)OC(=O)N1C[C@H](N)C[C@@H]1CO | 1g | 233627353
(2R,4R)-1-BOC-2-HYDROXYMETHYL-4-AMINOPYRROLIDINE HYDROCHLORIDE | AstaTech | 1279038-50-4 | MFCD11101163 | 252.740 | C10H21ClN2O3 | 95.000 | Cl.CC(C)(C)OC(=O)N1C[C@H](N)C[C@@H]1CO | 1g | 233627353
Medchemexpress LLC Bd-1008 dihydrobromide | 138356-09-9 | 98.1% | 463.08 g/mol | C15H24Br2Cl2N2 | 25 MG
BD-1008 dihydrobromide is a research-grade sigma (σ) receptor antagonist used in neuropharmacology and addiction-related studies. It is commonly applied in receptor binding assays, dopamine microdialysis, and preclinical pharmacology to probe σ receptor function and dopaminergic signaling.
- High affinity for σ1 and σ2 receptors (Ki ≈ 2 nM and 8 nM).
- Low affinity for D2 receptor and dopamine transporter, reducing off-target effects.
- High purity (98.07%), suitable for research applications.
- Available in small research pack sizes, including 25 MG.
- Solid form with molecular weight of approximately 463.08 g/mol.
Medchemexpress LLC CEBP gamma/CEBPG Hu 5ug
CEBP gamma/CEBPG protein is a transcription factor that regulates genes by binding to their promoter and enhancer regions It targets IL-4 and immunoglobulin heavy chains binding to enhancer elements PRE-I and GPE1 in the G-CSF gene promoter CEBP gamma/CEBPG Protein Human (His) is the recombinant human-derived CEBP gamma/CEBPG protein expressed by E coli with N-His labeled tag
