Lactones
Selleck Chemical LLC GA-017-E1145-25MG
GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2) which exerts inhibitory with IC50s against LATS1 and 2 of 4 10 0 79 and 3 92 0 42 nM respectively and competitively inhibits LATS1 and 2 against ATP with Ki (inhibition constant) values of 0 58 0 11 and 0 25 0 03 nM respectively
Medchemexpress LLC Gamma-secretase modulator 6 | 1255700-88-9 | 99.7% | 10 MG
Gamma-secretase modulator 6 is a high-purity research compound that modulates gamma-secretase activity and reduces Aβ42 secretion in cellular models (pIC50 8.1). It is provided as a solid or as a DMSO solution for preclinical biochemical and cellular research into Alzheimer's disease mechanisms.
- Inhibits Aβ42 secretion (pIC50 8.1).
- High purity suitable for research (99.68%).
- Available as solid and as a 10 mM DMSO solution.
- Molecular formula C25H26N6O2, molecular weight 442.51.
- Intended for preclinical and biochemical studies of amyloid processing.
Medchemexpress LLC SIRP gamma Cynomolg 10ug | 10ug
SIRP gamma Protein a member of signal-regulatory protein (SIRP) family is the only SIRP detected on T cells and activated NK cells SIRP gamma can bind CD47 providing T cells and NK cells with a cell surface molecule capable of interacting with CD47 SIRP gamma-CD47 interaction mediates strong cell-cell adhesion and supports T cell-APC contact enhancing antigen presentation and consequent T-cell proliferation and cytokine secretion SIRP gamma Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived SIRP gamma protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Bd-1008 dihydrobromide | 138356-09-9 | 98.1% | 463.08 g/mol | C15H24Br2Cl2N2 | 25 MG
BD-1008 dihydrobromide is a research-grade sigma (σ) receptor antagonist used in neuropharmacology and addiction-related studies. It is commonly applied in receptor binding assays, dopamine microdialysis, and preclinical pharmacology to probe σ receptor function and dopaminergic signaling.
- High affinity for σ1 and σ2 receptors (Ki ≈ 2 nM and 8 nM).
- Low affinity for D2 receptor and dopamine transporter, reducing off-target effects.
- High purity (98.07%), suitable for research applications.
- Available in small research pack sizes, including 25 MG.
- Solid form with molecular weight of approximately 463.08 g/mol.
Medchemexpress LLC CEBP gamma/CEBPG Hu 5ug
CEBP gamma/CEBPG protein is a transcription factor that regulates genes by binding to their promoter and enhancer regions It targets IL-4 and immunoglobulin heavy chains binding to enhancer elements PRE-I and GPE1 in the G-CSF gene promoter CEBP gamma/CEBPG Protein Human (His) is the recombinant human-derived CEBP gamma/CEBPG protein expressed by E coli with N-His labeled tag
![eMolecules 1630907-13-9 | tert-butyl rel-(3aR,5s,6aS)-5-amino-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxylate;hydrochloride | Pharmablock262.780 | C12H23ClN2O2 | 97.000 | Cl.CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H](N)C[C@@H]2C1 | 1g | 551074236](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502157691.JPG-250.jpg)
eMolecules 1630907-13-9 | tert-butyl rel-(3aR,5s,6aS)-5-amino-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxylate;hydrochloride | Pharmablock262.780 | C12H23ClN2O2 | 97.000 | Cl.CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H](N)C[C@@H]2C1 | 1g | 551074236
tert-butyl rel-(3aR,5s,6aS)-5-amino-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxylate;hydrochloride | Pharmablock | 1630907-13-9262.780 | C12H23ClN2O2 | 97.000 | Cl.CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H](N)C[C@@H]2C1 | 1g | 551074236