Lactones
Sigma Aldrich Fine Chemicals Biosciences (3aR)-(+)-Sclareolide natural, 97%, FG | 564-20-5 | MFCD00134168 | 100G
(3aR)-(+)-Sclareolide natural, 97%, FG | Purity: 97% | Mol Wt: 250.38 | 564-20-5 | MFCD00134168 | 100G
Medchemexpress LLC Duocarmycin GA | 1613286-59-1 | 99.0% | 476.95 g/mol | C26H25ClN4O3 | 5 MG
Duocarmycin GA is a DNA minor-groove alkylating agent used as an antibody-drug conjugate (ADC) payload and research cytotoxin; it is active against some multi-drug resistant cell lines.
- Purity 99.0% suitable for research applications.
- Molecular formula C26H25ClN4O3 and molecular weight 476.95 g/mol.
- CAS number 1613286-59-1 for unambiguous identification.
- Available in small packaging sizes for ADC development and in vitro research, including 5 MG.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC 9H-Xanthen-9-one, 1,3,6,7-tetrahydroxy-2,8-bis(3-methyl-2-buten-1-yl)- | 31271-07-5 | 396.43 | 5 MG
Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and a potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. It binds to thyroxine (T4)-binding sites and stabilizes the TTR tetramer. This compound exhibits a range of biological activities and is used in the study of metabolic disorders.
- Novel competitive 5-HT2A receptor antagonist
- Potent COX-2 inhibitor
- TTR profibrosis inhibitor
- Stabilizes the TTR tetramer
- Exhibits anti-inflammatory activity
- Exhibits antibacterial activity
- Exhibits antioxidant activity
- Exhibits anticancer activities
- Used in the study of metabolic disorders such as diabetes
![Medchemexpress LLC Pyrido[2,1-c][1,4]oxazin-6(1H)-one derivative, 3,4,5-trifluorophenyl substituted | 937812-80-1 | 99.8% | 483.48 g/mol | C26H24F3N3O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000298650.png-250.jpg)
Medchemexpress LLC Pyrido[2,1-c][1,4]oxazin-6(1H)-one derivative, 3,4,5-trifluorophenyl substituted | 937812-80-1 | 99.8% | 483.48 g/mol | C26H24F3N3O3 | 10 MG
gamma-Secretase modulator for research applications. This small-molecule modulator inhibits amyloid-β production and is supplied as a high-purity white to off-white solid for laboratory use. It is intended for in vitro and preclinical research on γ-secretase-related pathways and Alzheimer's disease mechanisms.
- Used to modulate amyloid-β production in research assays.
- High reported purity suitable for analytical and biological studies.
- Defined molecular weight and formula for reproducible experiments.
- White to off-white solid, easy to handle and store.
- Available in small research quantities (e.g., 10 mg) for assay development.
Sigma Aldrich Fine Chemicals Biosciences gamma-Octalactone natural100G
Octalactone is one of the flavor constituents of peaches oranges and sweet fortified wines.
eMolecules 3,5-Dichloro-4-(hydroxymethyl)phenol | 720679-54-9 | MFCD06797936 | 1g
Ambeed | 3,5-Dichloro-4-(hydroxymethyl)phenol | 1g | 602850251 | A500317 | | 720679-54-9 | MFCD06797936 | 193.020 | C7H6Cl2O2
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Medchemexpress LLC AMPK gamma 1/beta 2/alpha 2 heterotrimer protein | >90.0% | 10 UG
Recombinant human AMPK gamma 1/beta 2/alpha 2 heterotrimer protein produced in Sf9 insect cells with N-terminal His and GST tags. Supplied as a 0.22 μm filtered solution in Tris-NaCl buffer with stabilizers, the protein shows high purity and measurable kinase activity suitable for biochemical assays and structural studies. Store frozen and avoid repeated freeze-thaw cycles.
- Recombinant heterotrimeric AMPK composed of gamma 1, beta 2, and alpha 2 subunits.
- Expressed in Sf9 insect cells for eukaryotic folding and post-translational processing.
- N-terminal His and GST tags for affinity purification and detection.
- Purity greater than 90% as determined by reducing SDS-PAGE.
- Supplied in a stabilized buffer formulation containing Tris, NaCl, EDTA, DTT, glycerol, and antioxidants.
- Specific activity of 1-6 nmol/min/mg measured using SAMS peptide.
- Available in small aliquots to minimize freeze-thaw and preserve activity.
Medchemexpress LLC Fc gamma RIIIA (CD16a) protein, rat | ≥98.0% | 5 UG
Recombinant rat Fc gamma receptor IIIA (FcγRIIIA/CD16a) produced in HEK293 cells with a C-terminal His tag and supplied in solution. The protein is intended for in vitro studies of Fc-IgG interactions, antibody-dependent cellular cytotoxicity (ADCC), and receptor characterization; available in small quantities (5 μg) for assay-scale experiments.
- Recombinant rat FcγRIIIA/CD16a produced in mammalian HEK293 cells.
- C-terminal His tag enables purification and detection.
- Supplied in solution for immediate use in biochemical and cell-based assays.
- Suitable for Fc-IgG binding studies and ADCC assay development.
- High purity verified by reducing SDS-PAGE (batch result ≥98%).
Medchemexpress LLC Mitogen-activated protein kinase 12 (p38 gamma) | >95.0% | 10 UG
Recombinant human p38 gamma (MAPK12) protein expressed in Sf9 insect cells, supplied as a filtered solution for research use. The protein is provided at research-scale quantities, characterized by >95% purity (reducing SDS-PAGE), and shipped on dry ice to maintain cold-chain integrity.
- Expression host: Sf9 insect cells.
- Species: human.
- Purity greater than 95% by reducing SDS-PAGE.
- Formulated in 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.0, 0.2 μm filtered.
- Tag-free with potential residual N-terminal Gly-Pro.
- Shipped on dry ice and intended for research use only.
Sigma Aldrich Fine Chemicals Biosciences Simvastatin | 79902-63-9 | MFCD00072007 | 5mg
Simvastatin | Purity: ≥97% | Mol Wt: 418.57 | 79902-63-9 | MFCD00072007 | 5mg
eMolecules Alpha,alpha-dimethyl-gamma-butyrolactone | Combi-Blocks | 3709-08-8 | MFCD03844788 | 114.144 | C6H10O2 | 98.000 | CC1(C)CCOC1=O | 10g | 537623135
Alpha,alpha-dimethyl-gamma-butyrolactone | Combi-Blocks | 3709-08-8 | MFCD03844788 | 114.144 | C6H10O2 | 98.000 | CC1(C)CCOC1=O | 10g | 537623135
Ambeed transMethyl 4 hydroxymethyl cy
trans-Methyl 4-(hydroxymethyl)cyclohexanecarboxylate, 110928-44-4, 97%