Oxazinanes
Cayman Chemical Fingolimod hydrochloride
An immune modulator and a prodrug form of FTY720 phosphate; decreases the number of circulating lymphocytes in mice at 1 mg/kg; increases skin allograft survival in rats from 0.3-3 mg/kg; prevents disease development in a rat model of EAE; inhibits S1P lyase from 0.3-30 µM
TARGETMOL CHEMICALS INC COT INHIBITOR-1 HYDROCHL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cot inhibitor-1 hydrochloride is an inhibitor of tumor progression loci-2 kinase (IC50 = 28 nM) and inhibits the production of TNF-(alpha) in human whole blood (IC50 = 5.7 nM).
![eMolecules Pharmablock / tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate / 100mg / 551141200 / PBN20121589 / 0.000 / 309962-67-2 / MFCD09878596 / 214.309 / C11H22N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502517627.JPG-250.jpg)
eMolecules Pharmablock / tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate / 100mg / 551141200 / PBN20121589 / 0.000 / 309962-67-2 / MFCD09878596 / 214.309 / C11H22N2O2
Pharmablock / tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate / 100mg / 551141200 / PBN20121589 / 0.000 / 309962-67-2 / MFCD09878596 / 214.309 / C11H22N2O2
Cayman Chemical 3 4DIhydroxymndelIc AcId 250mg
An active metabolite of norepinephrine; scavenges superoxide radicals (IC50 = 130 nM) and reduces lipid peroxidation in cell-free assays; a chemoattractant for enterohemorrhagic E. coli; induces the expression of enterohemorrhagic E. coli virulence genes at 50 µM; increases the attachment of enterohemorrhagic E. coli to HeLa cells in vitro
AdipoGen 5-DTAF hydrochloride
Chemical. CAS 21811-74-5. Formula C23H12Cl2N4O5 . HCl. MW 495.3 . 36.5. Synthetic. 5-DTAF is highly reactive with proteins. Unlike other reactive fluoresceins, 5-DTAF not only reacts with amino groups, but also reacts with thiol groups and even directly reacts with hydroxy groups such as polysaccharides and other alcohols in aqueous solution at pH above 9. Due to its high reactivity, 5-DTAF is also used to label carbohydrates. Spectral properties Abs/Em = 492/517 nm
Medchemexpress LLC 5,6-dihydro-5-fluorouracil | 696-06-0 | MFCD00871150 | 99.9% | C4H5FN2O2 | 10MG
5,6-Dihydro-5-fluorouracil is a fluorinated dihydropyrimidine metabolite used as a research reagent and analytical standard in biochemical and medicinal chemistry studies. It is supplied as a solid, high-purity material suitable for in vitro assays, metabolite profiling, and method development.
- High purity of 99.9% for analytical reliability.
- Solid, white to off-white appearance for easy handling.
- Molecular formula C4H5FN2O2 and molecular weight 132.09 g/mol.
- Available in small pack sizes including 10 mg for scarce-sample experiments.
- Stable as a powder at -20°C for long-term storage.
- Includes structural identifier (SMILES) for informatics and modeling.
TARGETMOL CHEMICALS INC MIDAGLIZOLE HYDROCHLORID 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Midaglizole hydrochloride ((±)-DG5128) (DG5128) is a preferred (alpha)2-adrenoceptor antagonist. Midazolazole hydrochloride (DG5128) has an affinity for (alpha)2-adrenoceptor (pKi = 6.28) 7.4 times higher than that of (alpha)1-adrenoceptor. purity: 98%
Cayman Chemical Fingolimod hydrochloride
An immune modulator and a prodrug form of FTY720 phosphate; decreases the number of circulating lymphocytes in mice at 1 mg/kg; increases skin allograft survival in rats from 0.3-3 mg/kg; prevents disease development in a rat model of EAE; inhibits S1P lyase from 0.3-30 µM
Cayman Chemical Pargyline hydrochloride
An irreversible inhibitor of MAO (Kis = 15 and 1.8 μM for MAO-A and MAO-B, respectively); induces a moderate decrease of systolic blood pressure in unanaesthetized hypertensive rats but not normotensive WKR or Sprague-Dawley rats; prevents reactive oxygen species-mediated monocyte hypertrophy at a concentration of 10 µM
Cayman Chemical Fingolimod hydrochloride
An immune modulator and a prodrug form of FTY720 phosphate; decreases the number of circulating lymphocytes in mice at 1 mg/kg; increases skin allograft survival in rats from 0.3-3 mg/kg; prevents disease development in a rat model of EAE; inhibits S1P lyase from 0.3-30 µM
Apexbio Technology LLC Betaine hydrochloride 590-46-5 10mM (in 1mL DMSO)
Betaine hydrochloride (CAS 590-46-5) is a quaternary ammonium compound that serves as a methyl group donor in cellular metabolism notably participating in the methionine-homocysteine cycle to modulate homocysteine levels Extracted from natural sources such as wolfberry and Achyranthes this molecule is soluble in water and ethanol facilitating its use in various assay systems Betaine hydrochloride is frequently employed in biomedical research to investigate metabolic regulation methylation processes and osmoregulatory mechanisms The compound should be stored tightly sealed in cool dry conditions to maintain stability for experimental applications
Medchemexpress LLC HADA hydrochloride | 2253733-10-5 | 98.0% | 1 ML
HADA hydrochloride is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation.
- Blue fluorescent D-amino acid
- Efficiently incorporated into peptidoglycans of diverse bacterial species
- Allows specific and covalent probing of bacterial growth
- Minimal perturbation during bacterial growth probing
- Suitable for laboratory research applications
Medchemexpress LLC 4-Phenyl-7,8-dihydroxycoumarin | 842-01-3 | 99.4% | 10 MG
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative for research use only, and can be used for bronchiectasis research.
- Chemical formula: C15H10O4
- Molecular weight: 254.24
- Appearance: Solid, off-white to yellow
- Solubility: 100 mg/mL in DMSO
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Related disease areas: Neurological, Eye or Ear Disease, Inflammation or Immune System Disease, Neurodegenerative Disease, Parkinson's Disease
- Signaling pathways: Inflammation/Immunology, Metabolic Enzyme/Protease, Neuronal Signaling, COMT
Medchemexpress LLC 4-Phenyl-7,8-dihydroxycoumarin | 842-01-3 | 99.4% | 1 ML
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative primarily used for bronchiectasis research. It is intended for research use only and not for medical applications.
- High purity (99.35%)
- Supplied as a 10 mM solution in DMSO
- Appearance: off-white to yellow solid
- Molecular weight: 254.24
- Demonstrates cytotoxicity against human A375 cells with an IC50 of 39 μM
- Demonstrates cytotoxicity against human MRC5 cells with an IC50 of 47 μM
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Solution storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC ML204 hydrochloride | 2070015-10-8 | 99.7% | 1 ML
ML204 hydrochloride is a novel, potent, and selective TRPC4/TRPC5 channel inhibitor.
- Potent and selective TRPC4/TRPC5 channel inhibitor.
- Exhibits at least 19-fold selectivity against TRPC6.
- No appreciable effect on other TRP channels.
- Does not affect voltage-gated sodium, potassium, or Ca2+ channels.