Oxazinanes
AdipoGen Bupivacaine HCl monohydrate
Chemical. CAS 73360-54-0. Formula C18H28N2O . HCl . H2O. MW 288.4. 36.5 . 18.0. Synthetic. Bupivacaine is an amino amide local anesthetic that decreases current amplitude and inhibits whole cell K currents in Ca2-activated K channels and N-type voltage-gated KCNA and KCNC K channels. Bupivacaine also inhibits voltage-gated Na channels and tandem pore domain TASK-2/KCNK-5 K channels. The compound is cytotoxic at high concentrations inducing apoptosis and/or necrosis by interference with the mitochondrial energy transduction. Shown to inhibit aerobic ATP synthesis by i uncoupling of the oxidative phosphorylation OXPHOS and ii inhibition of the complex I of the respiratory. Other mechanisms include inhibition of the carnitine-acylcarnitine translocase or activation of the mitochondrial permeability transition pore MPTP.
TARGETMOL CHEMICALS INC LURASIDONE HYDROCHLORIDE 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist serotonin 5-HT7 receptor antagonist an antagonist of the adrenergic (alpha)2A and (alpha)2C receptors as well as a partial serotonin 5-HT1A receptor agonist. It is used in the treatment of schizophrenia and bipolar disorder. purity: 99%
Medchemexpress LLC Rhodamine B isothiocyanate | 36877-69-7 | MFCD00041787 | 98.0% | 536.09 g/mol | C29H30ClN3O3S | 5 MG
Rhodamine B isothiocyanate is a xanthene-derived fluorescent labeling reagent containing an isothiocyanate functional group for covalent conjugation to primary amines. Provided as a solid, it produces strong red fluorescence for biochemical labeling, microscopy, and fluorescence assays, and is suitable for preparing labeled proteins, peptides, and other biomolecules.
- Provides bright red fluorescence for sensitive detection and imaging.
- Reacts with primary amines via isothiocyanate chemistry for stable covalent labeling.
- High purity (~98.0%) for reproducible conjugation results.
- Solid form allows easy handling and long-term storage when protected from light.
- Compatible with common fluorescence detection systems and imaging filters.
eMolecules ChemScene Methyl pyrrolidine-3-carboxylate hydrochloride 5g 572228223 CS-W001842 198959-37-4 MFCD08436169 165.620 C6H12ClNO2
ChemScene Methyl pyrrolidine-3-carboxylate hydrochloride 5g 572228223 CS-W001842 198959-37-4 MFCD08436169 165.620 C6H12ClNO2
eMolecules Pharmablock tert-butyl (3R)-3-aminoazepane-1-carboxylate 10g 551084957 PB08164 1032684-85-7 MFCD11041391 214.309 C11H22N2O2
Pharmablock tert-butyl (3R)-3-aminoazepane-1-carboxylate 10g 551084957 PB08164 1032684-85-7 MFCD11041391 214.309 C11H22N2O2
eMolecules ChemScene Morpholine-2-carbonitrile hydrochloride 1g 632312733 CS-W005833 1205751-07-0 MFCD14582597 148.590 C5H9ClN2O
ChemScene Morpholine-2-carbonitrile hydrochloride 1g 632312733 CS-W005833 1205751-07-0 MFCD14582597 148.590 C5H9ClN2O
![eMolecules Combi-Blocks Inc. Chloro[(tricyclohexylphosphine)-2-(2'-aminobiphenyl)]palladium(II) 5g 642135149 QH-3261 96.000 1353658-81-7 [null] 590.520 C30H43ClNPPd](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695158.jpg-250.jpg)
eMolecules Combi-Blocks Inc. Chloro[(tricyclohexylphosphine)-2-(2'-aminobiphenyl)]palladium(II) 5g 642135149 QH-3261 96.000 1353658-81-7 [null] 590.520 C30H43ClNPPd
Combi-Blocks Inc. Chloro[(tricyclohexylphosphine)-2-(2'-aminobiphenyl)]palladium(II) 5g 642135149 QH-3261 96.000 1353658-81-7 [null] 590.520 C30H43ClNPPd
Apexbio Technology LLC Prilocaine hydrochloride 1786-81-8 10mM (in 1mL DMSO)
Prilocaine hydrochloride (CAS 1786-81-8) is a local anesthetic belonging to the amino amide class It functions by reversibly inhibiting voltage-gated sodium channels on neuronal cell membranes thereby blocking the initiation and propagation of nerve impulses This property makes it suitable for investigating neuronal excitability pain signaling and ion channel pharmacology in various preclinical models Prilocaine hydrochloride is commonly employed in studies requiring local anesthesia and serves as a reference compound for benchmarking novel anesthetic agents in research settings
Apexbio Technology LLC Etazolate hydrochloride 35838-58-5 10mM (in 1mL DMSO)
Etazolate hydrochloride (CAS 35838-58-5) is a small molecule inhibitor of phosphodiesterase-4 (PDE-4) and a selective modulator of the GABA-A receptor PDE-4 inhibition alters the release of inflammatory mediators through cAMP-dependent and independent pathways supporting its exploration in respiratory inflammatory diseases such as asthma and chronic obstructive pulmonary disease As a GABA-A receptor modulator Etazolate hydrochloride has been shown in cortical neuron models to stimulate -secretase-mediated sAPP production and reduce amyloid- neurotoxicity Clinical studies in Alzheimer s disease patients have indicated that combination therapy with acetylcholinesterase inhibitors is safe and well-tolerated
Selleck Chemical LLC Cyclopentolate Hydrochloride
Cyclopentolate is an antagonist of muscarinic acetylcholine receptors with Ki values of 1 62 27 5 and 2 63 nM for M1 M2 and M3 receptors respectively