Oxazinanes
Selleck Chemical LLC OTS514 hydrochloride
OTS514 is a highly potent TOPK(T-LAK cell-originated protein kinase) inhibitor with an IC50 value of 2 6 nM OTS514 induces cell cycle arrest and apoptosis
![Medchemexpress LLC Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, hydrochloride (1:2). | 161416-61-1 | 99.1% | 265.18 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, hydrochloride (1:2). | 161416-61-1 | 99.1% | 265.18 | 50 MG
Pozanicline dihydrochloride is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist, highly selective for α4β2- and α6β2-nAChR subtypes. It has been shown to reverse nicotine withdrawal-induced deficits in contextual fear conditioning in mice.
- Orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist.
- Highly selective for α4β2- and α6β2-nAChR subtypes.
- Involved in Phase 2 clinical trials for Attention Deficit Hyperactivity Disorder, Alzheimer's Disease, and Nicotine Addiction.
- Reverses nicotine withdrawal-induced deficits in contextual fear conditioning in mice.
eMolecules ChemScene cis-Cyclohexane-12-diamine 25g 536839956 CS-M3552 1436-59-5 MFCD00063746 114.192 C6H14N2
ChemScene cis-Cyclohexane-12-diamine 25g 536839956 CS-M3552 1436-59-5 MFCD00063746 114.192 C6H14N2
TARGETMOL CHEMICALS INC Ruboxistaurin hydrochloride
Also available in 1 mL, 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCbetaI and PKCbetaII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCbeta over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 uM for PKCη, -delta, -gamma, -alpha, - and -ζ respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src). Purity 98.44%
eMolecules Ambeed 147-Triazonane trihydrochloride 25g 570567817 A145596 58966-93-1 MFCD00074887 238.580 C6H18Cl3N3
Ambeed 147-Triazonane trihydrochloride 25g 570567817 A145596 58966-93-1 MFCD00074887 238.580 C6H18Cl3N3
eMolecules Combi-Blocks 2-Amino-4-methylpyridine 5g 482930475 NA-0108 98.000 695-34-1 MFCD00006321 108.144 C6H8N2
Combi-Blocks 2-Amino-4-methylpyridine 5g 482930475 NA-0108 98.000 695-34-1 MFCD00006321 108.144 C6H8N2
TARGETMOL CHEMICALS INC CC-401 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CC-401 Hydrochloride (CC401 HCl) is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor (Ki of 25 to 50 nM.)with potential antineoplastic activity. purity: 98%
Medchemexpress LLC 2,5(1H,6H)-quinolinedione, 7,8-dihydro | 15450-69-8 | MFCD00766821 | 99.9% | 163.17 g/mol | C9H9NO2 | 10 G
7,8-Dihydro-2,5(1H,6H)-quinolinedione (compound SF32) is a research-grade small molecule described in literature as a positive inotropic agent. It is supplied as a solid with high analytical purity and intended for laboratory research applications; refer to the manufacturer documentation and certificate of analysis for handling, storage, and stability details.
- High reported purity: 99.86%.
- Solid form; appearance light brown to light yellow.
- Stable under recommended storage: powder -20°C (3 years) or 4°C (2 years).
- Solvent storage guidance: -80°C for 6 months, -20°C for 1 month.
- Suitable for in vitro research as a positive inotropic agent.
- Available in multiple pack sizes for laboratory use.
- Supplied with a certificate of analysis for quality verification.
![eMolecules Pharmablock tert-butyl 3-amino-3-methyl-azepane-1-carboxylate 5g 719895415 PBWP717 1513512-18-9 [null] 228.336 C12H24N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694795.jpg-250.jpg)
eMolecules Pharmablock tert-butyl 3-amino-3-methyl-azepane-1-carboxylate 5g 719895415 PBWP717 1513512-18-9 [null] 228.336 C12H24N2O2
Pharmablock tert-butyl 3-amino-3-methyl-azepane-1-carboxylate 5g 719895415 PBWP717 1513512-18-9 [null] 228.336 C12H24N2O2
Cayman Chemical Methedrone hydrochloride
A phenethylamine, amphetamine, and cathinone derivative that acts as a triple reuptake/release/reversible MAO inhibitor; intended for use as a standard for the forensic analysis of samples that may contain this compound
Apexbio Technology LLC AMTB hydrochloride 1mg
AMTB hydrochloride (CAS 926023-82-7) is a selective antagonist of the TRPM8 ion channel effectively inhibiting TRPM8-mediated activation induced by agonists such as icilin with a reported pIC50 of approximately 6 23 In addition to its primary action AMTB hydrochloride also exhibits non-selective inhibitory effects on voltage-gated sodium channels (NaV) This compound is commonly utilized in biomedical research to investigate the role of TRPM8 channel activity alterations in the pathophysiology of bladder overactivity and bladder pain syndrome
![eMolecules Combi-Blocks 25-Diazaspiro[3.4]octane-5-carboxylic acid tert-butyl ester 1g 335385421 SS-8365 95.000 1086398-04-0 MFCD11501186 212.293 C11H20N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697932.jpg-250.jpg)
eMolecules Combi-Blocks 25-Diazaspiro[3.4]octane-5-carboxylic acid tert-butyl ester 1g 335385421 SS-8365 95.000 1086398-04-0 MFCD11501186 212.293 C11H20N2O2
Combi-Blocks 25-Diazaspiro[3.4]octane-5-carboxylic acid tert-butyl ester 1g 335385421 SS-8365 95.000 1086398-04-0 MFCD11501186 212.293 C11H20N2O2
TARGETMOL CHEMICALS INC HERBACETIN 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Herbacetin induces apoptosis in HepG2 cells by ROS and PI3K/Akt pathway. 2. Herbacetin suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation. purity: 99%
TARGETMOL CHEMICALS INC DIPQUO HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP) with an EC50 of 6.27 uM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-(beta).
Cayman Chemical O2545 hydrochloride
A potent water-soluble agonist of CB1 and CB2 receptors with Ki values of 1.5 and 0.32 nM, respectively; when dissolved in saline, is highly efficacious in mouse behavioral models when administered either intravenously or intracerebroventricularly