Oxazinanes
AdipoGen 5-DTAF hydrochloride
Chemical. CAS 21811-74-5. Formula C23H12Cl2N4O5 . HCl. MW 495.3 . 36.5. Synthetic. 5-DTAF is highly reactive with proteins. Unlike other reactive fluoresceins, 5-DTAF not only reacts with amino groups, but also reacts with thiol groups and even directly reacts with hydroxy groups such as polysaccharides and other alcohols in aqueous solution at pH above 9. Due to its high reactivity, 5-DTAF is also used to label carbohydrates. Spectral properties Abs/Em = 492/517 nm
AdipoGen Bupivacaine HCl monohydrate
Chemical. CAS 73360-54-0. Formula C18H28N2O . HCl . H2O. MW 288.4. 36.5 . 18.0. Synthetic. Bupivacaine is an amino amide local anesthetic that decreases current amplitude and inhibits whole cell K currents in Ca2-activated K channels and N-type voltage-gated KCNA and KCNC K channels. Bupivacaine also inhibits voltage-gated Na channels and tandem pore domain TASK-2/KCNK-5 K channels. The compound is cytotoxic at high concentrations inducing apoptosis and/or necrosis by interference with the mitochondrial energy transduction. Shown to inhibit aerobic ATP synthesis by i uncoupling of the oxidative phosphorylation OXPHOS and ii inhibition of the complex I of the respiratory. Other mechanisms include inhibition of the carnitine-acylcarnitine translocase or activation of the mitochondrial permeability transition pore MPTP.
TARGETMOL CHEMICALS INC CMF019 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CMF019 is a potent agonist of the Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ (pKis 8.58 8.49 and 8.71 for the human rat and mouse). purity: 98%
TARGETMOL CHEMICALS INC ZK-90055 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. ZK-90055 hydrochloride is a (beta)2 adrenergic receptor agonist used to study asthma. purity: 99%
Cayman Chemical SRT 1720 hydrochloride
A selective small molecule activator of SIRT1 that is 1,000-fold more potent than resveratrol; improves insulin sensitivity, lowers plasma, glucose and increases mitochondrial capacity in diet-induced obese and diabetic leptin-deficient ob/ob mice after one week of treatment with an oral dose of 100 mg/kg once daily.
Cayman Chemical Pargyline hydrochloride
An irreversible inhibitor of MAO (Kis = 15 and 1.8 μM for MAO-A and MAO-B, respectively); induces a moderate decrease of systolic blood pressure in unanaesthetized hypertensive rats but not normotensive WKR or Sprague-Dawley rats; prevents reactive oxygen species-mediated monocyte hypertrophy at a concentration of 10 µM
Cayman Chemical Pargyline hydrochloride
An irreversible inhibitor of MAO (Kis = 15 and 1.8 μM for MAO-A and MAO-B, respectively); induces a moderate decrease of systolic blood pressure in unanaesthetized hypertensive rats but not normotensive WKR or Sprague-Dawley rats; prevents reactive oxygen species-mediated monocyte hypertrophy at a concentration of 10 µM
eMolecules Ambeed 3-Boc-Aminopyrrolidine 5g 552513337 A100593 99724-19-3 MFCD00059040 186.255 C9H18N2O2
Ambeed 3-Boc-Aminopyrrolidine 5g 552513337 A100593 99724-19-3 MFCD00059040 186.255 C9H18N2O2
eMolecules Pharmablock tert-butyl (3R)-3-(methylamino)piperidine-1-carboxylate 10g 551141259 PBN20121606 203941-94-0 MFCD09752963 214.309 C11H22N2O2
Pharmablock tert-butyl (3R)-3-(methylamino)piperidine-1-carboxylate 10g 551141259 PBN20121606 203941-94-0 MFCD09752963 214.309 C11H22N2O2
![eMolecules Pharmablock tert-butyl cis-1233a4577a-octahydropyrrolo[23-c]pyridine-6-carboxylate 5g 551295774 PBV0076 1286755-20-1 MFCD28396680 226.320 C12H22N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695807.jpg-250.jpg)
eMolecules Pharmablock tert-butyl cis-1233a4577a-octahydropyrrolo[23-c]pyridine-6-carboxylate 5g 551295774 PBV0076 1286755-20-1 MFCD28396680 226.320 C12H22N2O2
Pharmablock tert-butyl cis-1233a4577a-octahydropyrrolo[23-c]pyridine-6-carboxylate 5g 551295774 PBV0076 1286755-20-1 MFCD28396680 226.320 C12H22N2O2
![eMolecules Pharmablock tert-butyl N-[(1S2S)-2-aminocyclobutyl]carbamate 1g 551123640 PBLL1453 1374222-18-0 [null] 186.255 C9H18N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695848.jpg-250.jpg)
eMolecules Pharmablock tert-butyl N-[(1S2S)-2-aminocyclobutyl]carbamate 1g 551123640 PBLL1453 1374222-18-0 [null] 186.255 C9H18N2O2
Pharmablock tert-butyl N-[(1S2S)-2-aminocyclobutyl]carbamate 1g 551123640 PBLL1453 1374222-18-0 [null] 186.255 C9H18N2O2