Oxazinanes

TARGETMOL CHEMICALS INC GIVINOSTAT HYDROCHLORIDE 5MG

Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Givinostat hydrochloride (ITF2357 hydrochloride) is an inhibitor of HDAC with IC50 of 198 and 157 nM for HDAC1 and HDAC3 respectively. Givinostat hydrochloride exhibits anti-inflammatory anti-angiogenic and antineoplastic activities. purity: 98%

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eMolecules​ 936644-39-2 | BUT-3-YNE-1-SULFONYL CHLORIDE | AstaTech | MFCD19598006 | 152.590 | C4H5ClO2S | 95.000 | ClS(=O)(=O)CCC#C | 1g | 716226761

BUT-3-YNE-1-SULFONYL CHLORIDE | AstaTech | 936644-39-2 | MFCD19598006 | 152.590 | C4H5ClO2S | 95.000 | ClS(=O)(=O)CCC#C | 1g | 716226761

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eMolecules​ 65934-74-9 | 4-Methyl-3-(trifluoromethyl)aniline | Ambeed | MFCD01631582 | 175.154 | C8H8F3N | 98.000 | Cc1ccc(N)cc1C(F)(F)F | 100g | 598444805

4-Methyl-3-(trifluoromethyl)aniline | Ambeed | 65934-74-9 | MFCD01631582 | 175.154 | C8H8F3N | 98.000 | Cc1ccc(N)cc1C(F)(F)F | 100g | 598444805

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eMolecules​ 1820647-38-8 | 2,2-difluoromorpholine hydrochloride | Pharmablock | MFCD29033956 | 159.560 | C4H8ClF2NO | 97.000 | Cl.FC1(F)CNCCO1 | 100mg | 799220939

2,2-difluoromorpholine hydrochloride | Pharmablock | 1820647-38-8 | MFCD29033956 | 159.560 | C4H8ClF2NO | 97.000 | Cl.FC1(F)CNCCO1 | 100mg | 799220939

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eMolecules​ 138027-02-8 | cis-6-Boc-octahydropyrrolo[3,4-b]morpholine | Activate Scientific456.584 | C22H40N4O6 | 95.000 | CC(C)(C)OC(=O)N1C[C@H]2NCCO[C@H]2C1.CC(C)(C)OC(=O)N1C[C@@H]2NCCO[C@@H]2C1 | 1g | 761006608

cis-6-Boc-octahydropyrrolo[3,4-b]morpholine | Activate Scientific | 138027-02-8456.584 | C22H40N4O6 | 95.000 | CC(C)(C)OC(=O)N1C[C@H]2NCCO[C@H]2C1.CC(C)(C)OC(=O)N1C[C@@H]2NCCO[C@@H]2C1 | 1g | 761006608

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eMolecules​ 885272-17-3 | tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate | Combi-Blocks, Inc. | MFCD08234981 | 226.320 | C12H22N2O2 | 97.000 | CC(C)(C)OC(=O)N1CCCC2(CNC2)C1 | 5g | 726030015

tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate | Combi-Blocks, Inc. | 885272-17-3 | MFCD08234981 | 226.320 | C12H22N2O2 | 97.000 | CC(C)(C)OC(=O)N1CCCC2(CNC2)C1 | 5g | 726030015

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eMolecules​ 62510-60-5 | (1,1-Dioxido-2,3-dihydro-3-thienyl)amine hydrochloride | Combi-Blocks, Inc. | MFCD00456625 | 169.620 | C4H8ClNO2S | 95.000 | Cl.NC1CS(=O)(=O)C=C1 | 5g | 603225993

(1,1-Dioxido-2,3-dihydro-3-thienyl)amine hydrochloride | Combi-Blocks, Inc. | 62510-60-5 | MFCD00456625 | 169.620 | C4H8ClNO2S | 95.000 | Cl.NC1CS(=O)(=O)C=C1 | 5g | 603225993

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Medchemexpress LLC Quizartinib dihydrochloride | 1132827-21-4 | MFCD18633276 | 99.8% | C29H34Cl2N6O4S | 10MG

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Quizartinib dihydrochloride is the dihydrochloride salt of quizartinib, a second-generation, type II FLT3 tyrosine kinase inhibitor used in research on FLT3-mutant acute myeloid leukemia. It is supplied as a white to off-white solid with high reported purity and is used in biochemical and cellular assays to study FLT3 signaling and inhibitor activity.

• High purity suitable for research applications.
• White to off-white solid form for straightforward handling.
• Molecular formula C29H34Cl2N6O4S and molecular weight 633.59 g/mol for accurate calculations.
• Stable when stored sealed and protected from moisture under recommended conditions.
• Available in small pack sizes appropriate for preclinical studies.

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Medchemexpress LLC Bx471 hydrochloride | 288262-96-4 | 99.9% | 1 ML

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BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective, non-peptide CCR1 antagonist (Ki = 1 nM) that shows approximately 250-fold selectivity over CCR2, CCR5, and CXCR4. It is supplied for research as a ready-to-use 10 mM solution in DMSO (1 mL) or as solid quantities for reconstitution, and is commonly used in studies of CCR1 pharmacology and inflammation.

• Potent CCR1 antagonist with Ki = 1 nM.
• Approximately 250-fold selectivity versus CCR2, CCR5, and CXCR4.
• Supplied as a 10 mM solution in DMSO (1 mL) or as solids for reconstitution.
• High purity suitable for research applications.

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Medchemexpress LLC 1-methyl-1,4-dihydronicotinamide | 17750-23-1 | AKOS006277282 | 95.0% | 138.17 g/mol | C7H10N2O | 10MG

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1-Methyl-1,4-dihydronicotinamide is a reduced nicotinamide derivative (CAS 17750-23-1) used as a research reagent with reported radical-scavenging activity. It is supplied as a yellow to orange solid, molecular formula C7H10N2O, molecular weight 138.17 g/mol, and typical purity of 95.0%.

• Radical scavenging activity reported in biochemical studies.
• Provided as a solid for preparation of laboratory stock solutions.
• Molecular formula C7H10N2O and molecular weight 138.17 g/mol.
• Typical purity 95.0% appropriate for research applications.
• Available in small mg-scale pack sizes for experimental use.

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eMolecules​ 1149-23-1 | Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate | Apollo Scientific US - Building Blocks | MFCD00005951 | 253.298 | C13H19NO4 | 95.000 | CCOC(=O)C1=C(C)NC(C)=C(C1)C(=O)OCC | 100g | 398005521

Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate | Apollo Scientific US - Building Blocks | 1149-23-1 | MFCD00005951 | 253.298 | C13H19NO4 | 95.000 | CCOC(=O)C1=C(C)NC(C)=C(C1)C(=O)OCC | 100g | 398005521

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Medchemexpress LLC Xamoterol hemifumarate | 73210-73-8 | MFCD00661103 | 99.9% | 397.43 g/mol | C20H29N3O9 | 50 MG

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Xamoterol hemifumarate is a selective, potent beta1-adrenergic receptor agonist used as a research reagent to study arrhythmogenesis and the relationship between β1-adrenergic stimulation and IKr.

• Selective beta1-adrenergic receptor agonist.
• Suitable for research into arrhythmogenesis and cardiac electrophysiology.
• Available in small solid quantities, including 50 MG.
• High purity (≈99.9%).
• Suitable for sealed, low-temperature storage.
• Includes CAS number 73210-73-8 for substance identification.

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Medchemexpress LLC Landiolol hydrochloride | 144481-98-1 | 546.05 | C25H40ClN3O8 | 100 MG

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Landiolol hydrochloride is an ultra-short-acting, highly selective β1-adrenergic receptor antagonist provided as a research reagent and analytical standard. It is used to study β1 receptor-mediated pharmacology in vitro and in vivo and is supplied with product documentation for safe handling and experimental use.

• Ultra-short-acting selective β1-adrenergic receptor antagonist.
• Commonly used as an analytical standard and pharmacological tool.
• Supplied as a powder suitable for in vitro and in vivo research.
• Available in multiple pack sizes, including 100 MG.
• Supplied with a datasheet and safety data sheet (SDS) for handling information.
• CAS number 144481-98-1 and molecular weight 546.05 g/mol for identification.

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Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 50 MG

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Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 50 MG

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Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 1 G

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Ipatasertib dihydrochloride is a highly selective and ATP-competitive pan-Akt inhibitor, demonstrating significant selectivity against Akt1, Akt2, and Akt3. It is intended for research use only.

• Highly selective and ATP-competitive pan-Akt inhibitor
• IC50s of 5, 18, and 8 nM for Akt1, Akt2, and Akt3, respectively
• Exhibits over 600-fold and over 100-fold selectivity for Akt1 against PKA and p70S6K
• Effective in xenograft models with Akt activation
• Achieves tumor growth delay, stasis, or regression in vivo

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