Oxazinanes
TARGETMOL CHEMICALS INC RACLOPRIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Raclopride is a selective antagonist of dopamine D2/D3 receptor. purity: 98%
TARGETMOL CHEMICALS INC VILAZODONE HYDROCHLORIDE 200MG
Also available in 10 mg 50 mg 100 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vilazodone Hydrochloride (EMD 68843) a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI) is utilized in treating of the major depressive disorder. purity: 99%
TARGETMOL CHEMICALS INC COT INHIBITOR-1 HYDROCHL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cot inhibitor-1 hydrochloride is an inhibitor of tumor progression loci-2 kinase (IC50 = 28 nM) and inhibits the production of TNF-(alpha) in human whole blood (IC50 = 5.7 nM).
![eMolecules Pharmablock / tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate / 100mg / 551141200 / PBN20121589 / 0.000 / 309962-67-2 / MFCD09878596 / 214.309 / C11H22N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502517627.JPG-250.jpg)
eMolecules Pharmablock / tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate / 100mg / 551141200 / PBN20121589 / 0.000 / 309962-67-2 / MFCD09878596 / 214.309 / C11H22N2O2
Pharmablock / tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate / 100mg / 551141200 / PBN20121589 / 0.000 / 309962-67-2 / MFCD09878596 / 214.309 / C11H22N2O2
Medchemexpress LLC 4-Phenyl-7,8-dihydroxycoumarin | 842-01-3 | 99.4% | 1 ML
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative primarily used for bronchiectasis research. It is intended for research use only and not for medical applications.
- High purity (99.35%)
- Supplied as a 10 mM solution in DMSO
- Appearance: off-white to yellow solid
- Molecular weight: 254.24
- Demonstrates cytotoxicity against human A375 cells with an IC50 of 39 μM
- Demonstrates cytotoxicity against human MRC5 cells with an IC50 of 47 μM
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Solution storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC ML204 hydrochloride | 2070015-10-8 | 99.7% | 1 ML
ML204 hydrochloride is a novel, potent, and selective TRPC4/TRPC5 channel inhibitor.
- Potent and selective TRPC4/TRPC5 channel inhibitor.
- Exhibits at least 19-fold selectivity against TRPC6.
- No appreciable effect on other TRP channels.
- Does not affect voltage-gated sodium, potassium, or Ca2+ channels.
Medchemexpress LLC IBT6A hydrochloride | 1553977-42-6 | 99.7% | 1 ML
IBT6A hydrochloride is an impurity of Ibrutinib. It is used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct. Ibrutinib is known as a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM.
- Impurity of Ibrutinib.
- Utilized in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.
- Can be used in the synthesis of Ibrutinib and Ibrutinib-based activity-based probes (ABPs).
- Relevant to the study of Ibrutinib, a selective, irreversible Btk inhibitor.
Medchemexpress LLC 4-Phenyl-7,8-dihydroxycoumarin | 842-01-3 | 99.35% | 50 MG
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative used in bronchiectasis research. This product is strictly for research purposes and not for sale to patients.
- Suitable for bronchiectasis research
- Powder storage: -20°C for 3 years, or 4°C for 2 years
- Storage in solvent: -80°C for 6 months, or -20°C for 1 month
Medchemexpress LLC Bomedemstat dihydrochloride | 99.6% | 592.54 | 10 MG
Bomedemstat (IMG-7289) dihydrochloride is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. It increases H3K4 and H3K9 methylation, which then alters gene expression. This compound exhibits anti-cancer activities by inhibiting cancer cell proliferation and inducing apoptosis.
- Orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor.
- Increases H3K4 and H3K9 methylation.
- Alters gene expression.
- Shows anti-cancer activities.
- Inhibits cancer cell proliferation.
- Induces apoptosis.
Medchemexpress LLC KHS101 hydrochloride | 1784282-12-7 | 99.65% | 375.92 | 100 MG
KHS101 hydrochloride is a selective neuronal differentiation inducer that can cross the blood-brain barrier. It exhibits selective cytotoxicity against glioblastoma multiforme (GBM) and interacts with transforming acidic coiled-coil protein (TACC3). This compound is suitable for GBM research.
- Selective neuronal differentiation inducer
- Crosses the blood-brain barrier
- Selective cytotoxicity against glioblastoma multiforme (GBM)
- Interacts with transforming acidic coiled-coil protein (TACC3)
- Useful in GBM research
Medchemexpress LLC Bomedemstat dihydrochloride | 99.6% | 592.54 | 100 MG
Bomedemstat dihydrochloride is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. It increases H3K4 and H3K9 methylation, altering gene expression. This compound exhibits anti-cancer activities by inhibiting cancer cell proliferation and inducing apoptosis.
- Increases H3K4 and H3K9 methylation
- Alters gene expression
- Inhibits cancer cell proliferation
- Induces apoptosis
Medchemexpress LLC Bomedemstat dihydrochloride | 99.55% | 592.54 | 25 MG
Bomedemstat dihydrochloride is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. It increases H3K4 and H3K9 methylation, which then alters gene expression. This compound exhibits anti-cancer activities by inhibiting cancer cell proliferation and inducing apoptosis, and is being investigated in multiple clinical trials.
- Selectively inhibits proliferation of Jak2V617F cells
- Induces apoptosis via BCL-XL and PUMA in a TP53-dependent manner
- Leads to cell cycle arrest in SET-2 cells
- Normalizes or improves blood cell counts in Mx-Jak2V617F mice
- Reduces spleen volumes and restores normal splenic architecture in animal models
Medchemexpress LLC Pyrithioxin dihydrochloride | 10049-83-9 | 98.0% | 10 MM 1 ML
Pyrithioxin (Pyritinol) dihydrochloride is the dihydrochloride salt of Pyrithioxin, an orally active neurodynamic compound. It promotes the metabolism of glucose and amino acids, increases carotid blood flow, and improves cerebral blood flow. Pyrithioxin exhibits anti-inflammation, anti-tumor, and neuroprotective effects. It is used in research related to cancer, inflammation, immunology, metabolic, and neurological diseases such as cerebral infarct, epilepsy, fibrosarcomas, and rheumatoid polyarthritis.
- Orally active neurodynamic compound
- Promotes glucose and amino acid metabolism
- Increases carotid blood flow
- Improves cerebral blood flow
- Exhibits anti-inflammation effect
- Exhibits anti-tumor effect
- Exhibits neuroprotective effect
- Used for research in cancer, inflammation, immunology, metabolic, and neurological diseases
Medchemexpress LLC 13,14-Dihydro-15-keto prostaglandin f2α | 27376-76-7 | 99.0% | 354.48 | 1 MG
13,14-Dihydro-15-keto Prostaglandin F2α is an endogenous metabolite found in blood, used in pregnancy research.
- Endogenous metabolite present in blood
- Used for the research of pregnancy
Medchemexpress LLC 13,14-Dihydro-15-keto-PGE2 | 363-23-5 | 352.47 | 1 MG
13,14-Dihydro-15-keto-PGE2 participates in *Bifidobacterium animalis* F1-7 to alleviate opioid-induced constipation by 5-HT pathway.
- Targets endogenous metabolite and 5-HT receptor
- Participates in metabolic enzyme/protease, GPCR/G protein, and neuronal signaling pathways
- Stored as a solution at -20°C for up to 2 years