Oxolanes
Sigma Aldrich 6,7-Dimethylquinoline-3-carboxylic acid
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Diacetone acrylamide
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 5-Bromo-2-nitroanisole
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 3-Aminotetrahydrofuran
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 4-Methoxy-6-methyl-2H-pyran-2-one
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Borane-ammonia complex
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Fine Chemicals Biosciences VHL Protein Complex Active
The VHL complex is a multi-subunit ubiquitin ligase composed of VHL, Elongin B, Elongin C, Cul2 and Rbx1. The VHL protein serves as the substrate recognition component and is linked by Elongin C to a heterodimeric Cul2/Rbx1 module that functions as a potent activator of the ubiquitination of target proteins by an E2 conjugating enzyme. Elongin B interacts with the complex through Elongin C and appears to stabilize the binding of Elongin C to VHL. The primary function of the VHL complex is to regulate HIF (hypoxia inducible factor) activity by targeting the hydroxylated HIF-1alpha subunit for ubiquitination and rapid proteasomal degradation under normoxic conditions. It therefore plays an important role in the regulation of hypoxia-inducible genes such as the vascular endothelial growth factor (VEGF) and glucose transport-1 (Glut-1). Mutations in VHL are associated with the inherited von Hippel-Lindau (VHL) cancer syndrome and numerous forms of renal cell carcinoma.
Medchemexpress LLC KTX-582 intermediate-2 | 2434850-07-2 | 495.37 g/mol | C21H27BrN4O5 | 25 MG
KTX-582 intermediate-2 is a synthetic chemical intermediate used in the preparation of KTX-582 and for antibody-drug conjugate (ADC) construction. It is used in medicinal chemistry applications related to IRAK4 degrader development.
- Intermediate for synthesis and ADC preparation.
- CAS number 2434850-07-2.
- Molecular formula C21H27BrN4O5.
- Molecular weight 495.37 g/mol.
- Sold in small research quantities; supplier catalog indicates a 25 MG package.
Medchemexpress LLC Isomannide (1,4:3,6-dianhydromannitol) | 641-74-7 | MFCD10698761 | 99.9% | 146.14 g/mol | C6H10O4 | 25 G
Isomannide (1,4:3,6-dianhydromannitol) is a small-molecule intermediate used in biochemical research and synthetic chemistry. Supplied as a powder with high reported purity, it is applied as a building block, reagent, or derivative scaffold in studies including viral infection models and protease-related pathways. For research use only.
- High purity (99.93%).
- Molecular formula C6H10O4; molecular weight 146.14 g/mol.
- Powder form for easy handling and weighing.
- Soluble in DMSO at ≥100 mg/mL (saturation not specified).
- Storage: powder stable at -20°C for up to 3 years; in solvent, store at -80°C for best stability.
- Intended use as an intermediate, reagent, or drug-derivative building block in research.
Medchemexpress LLC Isomannide (1,4:3,6-dianhydromannitol) | 641-74-7 | MFCD10698761 | 99.9% | 146.14 g/mol | C6H10O4 | 100 G
Isomannide (1,4:3,6-dianhydromannitol) is a small-molecule intermediate and biochemical reagent used in synthetic chemistry and biological research. It is supplied as a powder with high reported purity and strong DMSO solubility, and is commonly employed as a drug intermediate and in studies of HCV infection and KLK5/KLK7-related biology.
- Small-molecule intermediate for biochemical and synthetic research.
- Molecular formula C6H10O4; molecular weight 146.14 g/mol.
- Provided as a powder with high reported purity.
- Soluble in DMSO at ≥100 mg/mL.
- Used as a drug intermediate and in HCV and KLK5/KLK7 research.
- Storage: powder 4°C for 2 years or -20°C for 3 years; in solvent -80°C for 6 months.
Medchemexpress LLC Bambermycin | 11015-37-5 | 99.9% | 25 MG
Moenomycin complex is a class of antibacterial agents and PBP inhibitors, with Kd values ranging from 94 nM to 1690 nM against various bacterial PBPs. It inhibits bacterial growth by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs) and is used in the research of bacterial infections.
- Class of antibacterial agents and PBP inhibitors.
- Kd values ranging from 94 nM to 1690 nM against various bacterial PBPs.
- Inhibits bacterial growth by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs).
- Used in the research of bacterial infections.
- Binds to full-length class A PBPs from 16 bacterial species.
Medchemexpress LLC Moenomycin complex | 11015-37-5 | MFCD01742468 | 99.9% | 1583.6 g/mol | C69H107N4O35P | 5 MG
Moenomycin complex is a mixture of moenomycin antibiotics that potently inhibit bacterial transglycosylase enzymes, blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs) and disrupting peptidoglycan biosynthesis. Supplied as a powder for research use, it is used in studies of bacterial cell wall synthesis, antibiotic mechanism of action, and in vitro antibacterial assays.
- Potent transglycosylase inhibitor for mechanistic studies.
- Inhibits class A penicillin-binding proteins, blocking cell wall biosynthesis.
- High purity suitable for in vitro assays.
- Supplied as a powder for convenient storage and handling.
- Available in small pack sizes for scale-appropriate experiments.
- Useful in antibacterial activity assays and biochemical characterization.
Medchemexpress LLC Moenomycin complex | 11015-37-5 | 99.9% | 10 MG
Moenomycin complex is a class of antibacterial agents and PBP inhibitors, effective against various bacterial PBPs. It functions by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs), inhibiting bacterial growth. This product is intended for research use in bacterial infections.
- Appearance: Solid
- Color: Off-white to light yellow
- Solubility (in vitro): Ethanol : 25 mg/mL (requires ultrasonic and warming)
- Storage: Powder at -20°C for 3 years; in solvent at -80°C for 6 months, -20°C for 1 month
- Shipping: Room temperature in continental US; may vary elsewhere