Piperazines

Selleck Chemical LLC Piperazine Erastin-E1063-25MG

Piperazine Erastin is an analog of Erastin which can induces ferroptosis in cancer cells an iron-dependent form of nonapoptotic cell death

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Selleck Chemical LLC JTE-607 Dihydrochloride

JTE-607 Dihydrochloride is a prodrug compound that is converted to an active form by ester hydrolysis JTE-607 is a multiple cytokine production inhibitor that targets CPSF3 and inhibits pre-mRNA processing JTE-607 inhibits tumor necrosis factor (TNF)-alpha interleukin (IL)-1beta IL-6 IL-8 and IL-10 from LPS-stimulated human PBMCs with IC50 values of 11 nM 5 9 nM 8 8 nM 7 3 nM and 9 1 nM respectively

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eMolecules​ 110-85-0 | Piperazine | Chem-Impex | MFCD00005953 | 86.138 | C4H10N2 | 99.000 | C1CNCCN1 | 5kg | 272385526

Piperazine | Chem-Impex | 110-85-0 | MFCD00005953 | 86.138 | C4H10N2 | 99.000 | C1CNCCN1 | 5kg | 272385526

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Apexbio Technology LLC LDK378 dihydrochloride 1380575-43-8 100mg

LDK378 dihydrochloride (CAS 1380575-43-8) is a potent inhibitor of anaplastic lymphoma kinase (ALK) a receptor tyrosine kinase in the insulin receptor superfamily Demonstrating an in vitro IC50 of 200 pM against ALK LDK378 also inhibits IGF-1R InsR and STK22D with IC50 values of 8 nM 7 nM and 23 nM respectively In cellular assays LDK378 suppresses proliferation of Ba/F3 cells expressing NPM-ALK and Karpas-299 human non-Hodgkin lymphoma cells with IC50 values of 22 8 nM and 26 nM This compound serves as a valuable tool for investigating ALK-driven signaling pathways and potential therapeutic strategies in oncology research

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eMolecules​ 57260-71-6 | 1-Boc-piperazine | Oakwood Chemicals | MFCD00075265 | 186.255 | C9H18N2O2 | 98.000 | CC(C)(C)OC(=O)N1CCNCC1 | 1g | 480117337

1-Boc-piperazine | Oakwood Chemicals | 57260-71-6 | MFCD00075265 | 186.255 | C9H18N2O2 | 98.000 | CC(C)(C)OC(=O)N1CCNCC1 | 1g | 480117337

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Apexbio Technology LLC IT1t dihydrochloride 1092776-63-0 100mg

IT1t dihydrochloride (CAS 1092776-63-0) is a small-molecule antagonist targeting the chemokine receptor CXCR4 It is designed to inhibit CXCR4-mediated signaling by disrupting interactions with its natural ligand CXCL12 as well as the HIV envelope protein gp120 thereby interfering with cellular chemotaxis and viral entry mechanisms IT1t dihydrochloride exerts its biological activity primarily by antagonizing CXCR4 to inhibit receptor-mediated Ca2 mobilization and virus attachment In in vitro assays IT1t dihydrochloride demonstrates potent inhibition with IC50 values of approximately 8 nM in human CXCR4 receptor binding assays 1 1 nM in Ca2 mobilization assays and 7 nM in HIV attachment assays Based on these pharmacological properties IT1t dihydrochloride holds research potential in CXCR4-related signaling and HIV entry studies

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eMolecules​ 227783-08-6 | (1S,3R)-3-(ETHOXYCARBONYL)CYCLOHEXANECARBOXYLIC ACID | AstaTech | MFCD23701519 | 200.234 | C10H16O4 | 95.000 | CCOC(=O)[C@@H]1CCC[C@@H](C1)C(O)=O | 0.25g | 532624357

(1S,3R)-3-(ETHOXYCARBONYL)CYCLOHEXANECARBOXYLIC ACID | AstaTech | 227783-08-6 | MFCD23701519 | 200.234 | C10H16O4 | 95.000 | CCOC(=O)[C@@H]1CCC[C@@H](C1)C(O)=O | 0.25g | 532624357

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Medchemexpress LLC It1t dihydrochloride | 1092776-63-0 | MFCD22683853 | ≥98.0% | 479.57 g/mol | C21H36Cl2N4S2 | 10 MG

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IT1t dihydrochloride is a small-molecule antagonist of the chemokine receptor CXCR4, used in research to study CXCL12/CXCR4 signaling and ligand binding. It inhibits the CXCL12-CXCR4 interaction with a reported IC50 of about 2.1 nM and is provided as the dihydrochloride salt for improved stability.

• Potent CXCR4 antagonist with IC50 ≈2.1 nM.
• Suitable for receptor binding and functional assays.
• Supplied as the dihydrochloride salt to improve stability.
• Soluble in water (≈50 mg/mL) and in DMSO (≥30 mg/mL).
• Molecular formula C21H36Cl2N4S2; molecular weight 479.57 g/mol.
• High reported purity (≥95%-≥98% depending on supplier).
• Typical research pack size 10 MG.

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Aobchem 1-[4-(1-Hydroxy-1-methylethyl)phenyl]ethanone | ≥95% | CAS 54549-72-3 | C11H14O2 | 1g

1-[4-(1-Hydroxy-1-methylethyl)phenyl]ethanone | ≥95% | CAS 54549-72-3 | C11H14O2 | 1g

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Medchemexpress LLC 4-BENZYLOXYCARBONYL 25 mg

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4-BENZYLOXYCARBONYL 25MG

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Medchemexpress LLC 3-TERT-BUTOXYCARBON 500 mg

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3-TERT-BUTOXYCARBON 500MG

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Medchemexpress LLC 4-(1-methylethyl)phenyl diphenyl phosphate | 55864-04-5 | MFCD00377267 | 368.36 | C21H21O4P | 50 MG

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4-(1-Methylethyl)phenyl diphenyl phosphate is an organophosphate flame retardant supplied for research use. It is described by the manufacturer with key chemical identifiers and handling guidance.

• Organophosphate flame retardant used in materials research
• Chemical identifiers: CAS 55864-04-5; formula C21H21O4P
• Molecular weight 368.36 g·mol⁻¹
• Available in small research pack sizes, for example 50 MG
• Supplied for research use only; not for human or clinical use
• Refer to the Certificate of Analysis and SDS for storage and handling instructions

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Medchemexpress LLC 2-(1-methylethyl)phenyl diphenyl phosphate | 64532-94-1 | MFCD00870203 | 97.0% | 368.36 g/mol | C21H21O4P | 50 MG

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2-(1-Methylethyl)phenyl diphenyl phosphate is an organophosphate flame retardant supplied for research use. It is employed as an additive in materials and polymer studies to assess flame retardancy and thermal behavior.

• Organophosphate flame retardant for materials research.
• CAS number 64532-94-1 and molecular weight 368.36 g/mol.
• Molecular formula C21H21O4P.
• Available in small pack sizes suitable for laboratory testing (25 mg-10 g).
• Lot-specific purity reported on the Certificate of Analysis; refer to CoA for exact value.
• Refer to the safety data sheet for handling and storage requirements.

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Selleck Chemical LLC MPP dihydrochloride

Methyl-piperidino-pyrazole (MPP) dihydrochloride is a highly selective antagonist for estrogen receptor alpha (ER ) with an affinity 200 times greater than for estrogen receptor beta (ER ) It inhibits 17 -estradiol binding to ER by inducing conformational changes that alter the receptor s binding site and also increases the energy required for genistein s interaction with ER

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Apexbio Technology LLC MPP dihydrochloride(Synonyms: MPP dihydrochloride, Methyl-piperidino-pyrazole dihydrochloride, ER-alpha antagonist MPP), 50mg, CAS: 911295-24-4.

MPP dihydrochloride (CAS 911295-24-4) is a selective modulator of estrogen receptor (ER) activity demonstrating both agonist and antagonist properties Through modulation of ER-mediated signaling pathways this compound counteracts the biological effects driven by -estradiol inducing apoptosis specifically in ovarian and endometrial cancer cell types Due to its targeted interaction with ER MPP dihydrochloride serves as a research tool for investigating estrogen receptor pathways and their implications in oncology

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