Piperazinoazepines
Mianserin hydrochloride
CAS: 21535-47-7 Molecular Formula: C18H21ClN2 Molecular Weight (g/mol): 300.83 MDL Number: MFCD00055072 InChI Key: YNPFMWCWRVTGKJ-UHFFFAOYNA-N Synonym: mianserin hydrochloride,mianserine hydrochloride,mianserin hcl,athymil,bolvidon,tolvon,tolvin,org gb 94,lerivon PubChem CID: 68551 ChEBI: CHEBI:31843 IUPAC Name: hydrogen 5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene chloride SMILES: [H+].[Cl-].CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
Mirtazapine, 98%
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.35 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Mianserin Hydrochloride 98.0+%, TCI America™
CAS: 21535-47-7 Molecular Formula: C18H21ClN2 Molecular Weight (g/mol): 300.83 MDL Number: MFCD00055072 InChI Key: YNPFMWCWRVTGKJ-UHFFFAOYNA-N Synonym: mianserin hydrochloride,mianserine hydrochloride,mianserin hcl,athymil,bolvidon,tolvon,tolvin,org gb 94,lerivon PubChem CID: 68551 ChEBI: CHEBI:31843 IUPAC Name: hydrogen 5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene chloride SMILES: [H+].[Cl-].CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
Mirtazapine 98.0+%, TCI America™
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.36 MDL Number: MFCD00865427 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Medchemexpress LLC Mirtazapine | 85650-52-8 | >99.9% | 265.36 | 100 MG
Mirtazapine | 85650-52-8 | >99.9% | 265.36 | 100 MG
Apexbio Technology LLC Mirtazapine 85650-52-8 10mM (in 1mL DMSO)
Mirtazapine is a small-molecule antagonist targeting central presynaptic 2-adrenergic receptors as well as serotonin 5-HT2 and 5-HT3 receptors and central histamine H1 receptors It is designed to modulate monoaminergic neurotransmission thereby affecting mood regulation pathways Mirtazapine exerts its biological activity primarily through selective antagonism of central presynaptic 2-adrenergic receptors inducing increased synaptic release of norepinephrine and serotonin It also antagonizes serotonin 5-HT2 and 5-HT3 receptors Based on these pharmacological properties mirtazapine holds research potential in the fields of neuroscience and psychopharmacology particularly for studies involving depressive disorders anxiety conditions and mood regulation
Selleck Chemical LLC Mirtazapine S2016-50mg
Mirtazapine (Org3770 6-Azamianserin) is an adrenergic and seroton receptor antagonist used to treat depression
TARGETMOL CHEMICALS INC MIRTAZAPINE 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and has been linked to rare instances of clinically apparent acute liver injury. purity: 99%
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 25 MG
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist, enhancing the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Antagonizes 5-HT2, 5-HT3, histamine H1, and α2-adrenoceptors
- Enhances norepinephrine and 5-HT1A-mediated serotonergic transmission
- Reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes in vitro
- Inhibits Con A-induced liver injury in vivo by suppressing hepatic macrophage/monocyte activation
- Decreases pro-inflammatory cytokine and chemokine production and reduces neutrophil recruitment into the liver in vivo
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.95% | 50 MG
Mirtazapine (Standard) is the analytical standard of Mirtazapine, intended for research and analytical applications. It is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent, acting as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist. This compound is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard for Mirtazapine
- Intended for research and analytical applications
- Potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent
- Acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist
- Used in qualitative, quantitative and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC Mirtazapine-d3 | 1216678-68-0 | 99.7% | 1 MG
Mirtazapine-d3 is a deuterium labeled Mirtazapine, a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It functions by blocking 5-HT2 and 5-HT3 receptors. This compound is for research use only and can be utilized as a tracer or an internal standard for quantitative analysis.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits 5-HT2 receptors
- Inhibits 5-HT3 receptors
- Deuterium labeled compound
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 50 MG
Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist.
- Potent and orally active noradrenergic and specific serotonergic antidepressant.
- Antagonizes adrenergic α2-autoreceptors and α2-heteroreceptors, and blocks 5-HT2 and 5-HT3 receptors.
- Enhances the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Significantly reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes in vitro.
- Inhibits hepatic innate immune networks to attenuate immune-mediated liver injury in mice in vivo.
- Suppresses Con A-induced increases in hepatic ICAM-1 expression, reducing neutrophil recruitment into the liver.
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 1 ML
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It functions as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist. Mirtazapine enhances the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Antagonizes adrenergic α2-autoreceptors and α2-heteroreceptors
- Blocks 5-HT2 and 5-HT3 receptors
- Enhances norepinephrine release
- Enhances 5-HT1A-mediated serotonergic transmission
- Reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes
- Inhibits hepatic macrophage/monocyte activation and decreases pro-inflammatory cytokine and chemokine production
Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 1 G
Mianserin hydrochloride is an orally active H1 receptor antagonist that can activate κ-opioid and octapamine receptors. It increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and dynorphin A-induced MAPK phosphorylation. This compound modulates social and exploratory behaviour, raises electroconvulsive thresholds, and can be used for research of neurological diseases, including depression and epilepsy.
- Orally active H1 receptor antagonist
- Activates κ-opioid and octapamine receptors
- Increases ERK1/2 and CREB phosphorylation
- Antagonizes full κ-opioid agonist and dynorphin A-induced MAPK phosphorylation
- Modulates social and exploratory behaviour
- Raises electroconvulsive thresholds
- Used for research of neurological diseases, such as depression and epilepsy
Medchemexpress LLC Mirtazapine | 85650-52-8 | MFCD00865427 | 265.36 | C17H19N3 | 10 MG
Mirtazapine analytical reference standard for research and analytical applications, provided as a small-mass powdered material suitable for preparing stock solutions and calibrants. It represents the standard form of mirtazapine used in method development, calibration, and quality control workflows.
- Analytical reference suitable for method development and calibration.
- Used in studies targeting 5-HT, histamine H1, and adrenergic receptors.
- Molecular formula C17H19N3 and molecular weight 265.36 g/mol.
- Available in small mass packs (for example, 1 mg, 5 mg, 10 mg) for stock preparation.
- Storage guidance provided for powder and solutions to preserve stability.