Piperazinoazepines
Mianserin hydrochloride
CAS: 21535-47-7 Molecular Formula: C18H21ClN2 Molecular Weight (g/mol): 300.83 MDL Number: MFCD00055072 InChI Key: YNPFMWCWRVTGKJ-UHFFFAOYNA-N Synonym: mianserin hydrochloride,mianserine hydrochloride,mianserin hcl,athymil,bolvidon,tolvon,tolvin,org gb 94,lerivon PubChem CID: 68551 ChEBI: CHEBI:31843 IUPAC Name: hydrogen 5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene chloride SMILES: [H+].[Cl-].CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
Mirtazapine, 98%
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.35 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Mianserin Hydrochloride 98.0+%, TCI America™
CAS: 21535-47-7 Molecular Formula: C18H21ClN2 Molecular Weight (g/mol): 300.83 MDL Number: MFCD00055072 InChI Key: YNPFMWCWRVTGKJ-UHFFFAOYNA-N Synonym: mianserin hydrochloride,mianserine hydrochloride,mianserin hcl,athymil,bolvidon,tolvon,tolvin,org gb 94,lerivon PubChem CID: 68551 ChEBI: CHEBI:31843 IUPAC Name: hydrogen 5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene chloride SMILES: [H+].[Cl-].CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
Mirtazapine 98.0+%, TCI America™
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.36 MDL Number: MFCD00865427 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Medchemexpress LLC Mirtazapine | 85650-52-8 | MFCD00865427 | 99.9% | 265.36 | C17H19N3 | 10 MG
Mirtazapine is a tetracyclic antidepressant used in research to probe noradrenergic and specific serotonergic mechanisms. This research-grade 10 mg sample is supplied as a solid for laboratory use and is characterized by its reported high purity and defined molecular properties.
- Potent NaSSA agent for studies of noradrenergic and serotonergic pathways.
- Antagonist of 5-HT2, 5-HT3, H1, and α2 receptors.
- High reported purity (99.9%) suitable for analytical and in vitro assays.
- Molecular formula C17H19N3 and molecular weight 265.36 aid compound identification.
- Primarily metabolized by CYP1A2, CYP2D6, and CYP3A4, relevant for metabolism studies.
Medchemexpress LLC Mirtazapine-d3 | 1216678-68-0 | MFCD09841051 | 98.6% | 268.38 | C17H16D3N3 | 10 MG
Mirtazapine-d3 is a deuterium-labeled analogue of mirtazapine used as an internal standard and tracer for quantitative analytical methods. It delivers a mass-shifted reference for accurate quantitation in pharmacokinetic, bioanalytical, and metabolite studies, improving precision in LC-MS, GC-MS, and NMR assays.
- Deuterium-labeled internal standard for quantitative analysis.
- Compatible with LC-MS, GC-MS, and NMR techniques.
- High purity for consistent analytical performance.
- Powder form with defined cold-storage stability.
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 25 MG
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist, enhancing the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Antagonizes 5-HT2, 5-HT3, histamine H1, and α2-adrenoceptors
- Enhances norepinephrine and 5-HT1A-mediated serotonergic transmission
- Reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes in vitro
- Inhibits Con A-induced liver injury in vivo by suppressing hepatic macrophage/monocyte activation
- Decreases pro-inflammatory cytokine and chemokine production and reduces neutrophil recruitment into the liver in vivo
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.95% | 50 MG
Mirtazapine (Standard) is the analytical standard of Mirtazapine, intended for research and analytical applications. It is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent, acting as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist. This compound is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard for Mirtazapine
- Intended for research and analytical applications
- Potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent
- Acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist
- Used in qualitative, quantitative and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC Mirtazapine-d3 | 1216678-68-0 | 99.7% | 1 MG
Mirtazapine-d3 is a deuterium labeled Mirtazapine, a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It functions by blocking 5-HT2 and 5-HT3 receptors. This compound is for research use only and can be utilized as a tracer or an internal standard for quantitative analysis.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits 5-HT2 receptors
- Inhibits 5-HT3 receptors
- Deuterium labeled compound
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 50 MG
Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist.
- Potent and orally active noradrenergic and specific serotonergic antidepressant.
- Antagonizes adrenergic α2-autoreceptors and α2-heteroreceptors, and blocks 5-HT2 and 5-HT3 receptors.
- Enhances the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Significantly reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes in vitro.
- Inhibits hepatic innate immune networks to attenuate immune-mediated liver injury in mice in vivo.
- Suppresses Con A-induced increases in hepatic ICAM-1 expression, reducing neutrophil recruitment into the liver.
Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 200 MG
Mianserin hydrochloride | 21535-47-7 | 99.95% | 200 MG
Selleck Chemical LLC Mirtazapine S2016-10mg
Mirtazapine (Org3770 6-Azamianserin) is an adrenergic and seroton receptor antagonist used to treat depression
Sigma Aldrich Fine Chemicals Biosciences Mirtazapine >=98% (HPLC) | 85650-52-8 | MFCD00865427 | 50MG
Mirtazapine >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 265.35 | 85650-52-8 | MFCD00865427 | 50MG
Medchemexpress LLC Mirtazapine | 85650-52-8 | MFCD00865427 | 265.36 | C17H19N3 | 10 MG
Mirtazapine analytical reference standard for research and analytical applications, provided as a small-mass powdered material suitable for preparing stock solutions and calibrants. It represents the standard form of mirtazapine used in method development, calibration, and quality control workflows.
- Analytical reference suitable for method development and calibration.
- Used in studies targeting 5-HT, histamine H1, and adrenergic receptors.
- Molecular formula C17H19N3 and molecular weight 265.36 g/mol.
- Available in small mass packs (for example, 1 mg, 5 mg, 10 mg) for stock preparation.
- Storage guidance provided for powder and solutions to preserve stability.
Medchemexpress LLC Mianserin | 24219-97-4 | 99.42% | 25 MG
Mianserin is an orally active H1 receptor antagonist that can also activate κ-opioid and octopamine receptors. It increases ERK1/2 and CREB phosphorylation and antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation. Mianserin modulates social and exploratory behavior and raises electroconvulsive thresholds. It is used in the research of neurological diseases such as depression and epilepsy.
- Orally active H1 receptor antagonist
- Activates κ-opioid receptor and octopamine receptor
- Increases ERK1/2 and CREB phosphorylation
- Antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds
- Useful for research into neurological diseases like depression and epilepsy