Piperazinoazepines
Mianserin hydrochloride
CAS: 21535-47-7 Molecular Formula: C18H21ClN2 Molecular Weight (g/mol): 300.83 MDL Number: MFCD00055072 InChI Key: YNPFMWCWRVTGKJ-UHFFFAOYNA-N Synonym: mianserin hydrochloride,mianserine hydrochloride,mianserin hcl,athymil,bolvidon,tolvon,tolvin,org gb 94,lerivon PubChem CID: 68551 ChEBI: CHEBI:31843 IUPAC Name: hydrogen 5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene chloride SMILES: [H+].[Cl-].CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
Mirtazapine, 98%
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.35 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Mianserin Hydrochloride 98.0+%, TCI America™
CAS: 21535-47-7 Molecular Formula: C18H21ClN2 Molecular Weight (g/mol): 300.83 MDL Number: MFCD00055072 InChI Key: YNPFMWCWRVTGKJ-UHFFFAOYNA-N Synonym: mianserin hydrochloride,mianserine hydrochloride,mianserin hcl,athymil,bolvidon,tolvon,tolvin,org gb 94,lerivon PubChem CID: 68551 ChEBI: CHEBI:31843 IUPAC Name: hydrogen 5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene chloride SMILES: [H+].[Cl-].CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
Mirtazapine 98.0+%, TCI America™
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.36 MDL Number: MFCD00865427 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 500 MG
Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It functions as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist, influencing norepinephrine and 5-HT1A-mediated serotonergic transmission. It is primarily metabolized by CYP1A2, CYP2D6, and CYP3A4.
- Potent and orally active antidepressant
- Acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist
- Enhances release of norepinephrine
- Enhances 5-HT1A-mediated serotonergic transmission
- Reduces activation-induced release of cytokine/chemo kine mediators from human CD14+ monocytes in vitro
- Inhibits Con A-induced liver injury in vivo by suppressing hepatic macrophage/monocyte activation and pro-inflammatory cytokine production
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 200 MG
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist. Its metabolism is primarily handled by cytochrome P450 isoenzymes CYP1A2, CYP2D6, and CYP3A4.
- Acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist
- Enhances norepinephrine and 5-HT1A-mediated serotonergic transmission
- Significantly reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes
- Inhibits Con A-induced liver injury by suppressing hepatic macrophage/monocyte activation
Medchemexpress LLC S-mirtazapine | 61337-87-9 | MFCD00006761 | 99.8% | 265.35 g/mol | C17H19N3 | 10 MG
(S)-Mirtazapine is the S(+)-enantiomer of mirtazapine, provided as a solid research chemical for laboratory and analytical use. For research use only; not for human or clinical use.
- High purity: 99.76% (enantiomeric excess 98.35%).
- Chemical formula: C17H19N3; molecular weight: 265.35 g/mol.
- Appearance: off-white to light yellow powder.
- Solubility: ≥100 mg/mL in DMSO; use newly opened DMSO due to hygroscopicity.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Pack sizes suitable for small-scale research, including 10 mg quantities.
Medchemexpress LLC (S)-Mirtazapine | 61337-87-9 | 99.8% | 5 MG
(S)-Mirtazapine ((S)-Org3770) is an S(+)-enantiomer of Mirtazapine, exhibiting pronociceptive properties within an animal model of acute thermal nociception. It functions as a stereoselective 5-HT2 receptor antagonist and undergoes metabolism by CYP2D6 and CYP1A2.
- It is an S(+)-enantiomer of Mirtazapine.
- It has pronociceptive properties in an animal model of acute thermal nociception.
- It is a stereoselective 5-HT2 receptor antagonist.
- It is metabolized by CYP2D6 and CYP1A2.
- The molecular weight is 265.35.
- The chemical formula is C17H19N3.
- It appears as a solid.
- The color ranges from off-white to light yellow.
- The purity is 99.76%.
- The enantiomeric excess is 98.35%.
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 5 MG
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It functions as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist.
- Antagonizes adrenergic α2-autoreceptors and α2-heteroreceptors
- Blocks 5-HT2 and 5-HT3 receptors
- Enhances norepinephrine release and 5-HT1A-mediated serotonergic transmission
- Metabolized by cytochrome P450 isoenzymes CYP1A2, CYP2D6, and CYP3A4
- Reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes
- Inhibits Con A-induced liver injury
eMolecules 61337-87-9 | Medchem Express | (S)-Mirtazapine | 5mg | 761506639 | HY-B0352A | 265.36 | C17H19N3
Medchem Express | (S)-Mirtazapine | 5mg | 761506639 | HY-B0352A | 61337-87-9 | 265.360 | C17H19N3
Medchemexpress LLC Mianserin | 24219-97-4 | 99.4% | 50 MG
Mianserin is an orally active H1 receptor antagonist that can activate κ-opioid and octopamine receptors. It increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation. It modulates social and exploratory behavior and raises electroconvulsive thresholds. Mianserin is used for research of neurological diseases such as depression and epilepsy.
- Orally active H1 receptor antagonist
- Activates κ-opioid receptor
- Activates octopamine receptor
- Increases ERK1/2 and CREB phosphorylation
- Antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds
- Useful for research of neurological diseases like depression and epilepsy
Medchemexpress LLC Mianserin | 24219-97-4 | 99.4% | 5 MG
Mianserin (Mianserine) is an orally active H1 receptor antagonist. It can activate κ-opioid receptors and octopamine receptors. Mianserin increases ERK1/2 and CREB phosphorylation and antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation. It modulates social and exploratory behavior and raises electroconvulsive thresholds. It is used in research for neurological diseases such as depression and epilepsy.
- Orally active H1 receptor antagonist
- Activates κ-opioid and octopamine receptors
- Increases ERK1/2 and CREB phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds
- Used in research for neurological diseases such as depression and epilepsy
Medchemexpress LLC Mirtazapine | 85650-52-8 | MFCD00865427 | 99.95% | 100 MG
Mirtazapine (Standard) is the analytical standard of Mirtazapine, intended for research and analytical applications. It is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. Mirtazapine is also a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist with pKi values of 8.05, 8.1, 9.3, and 6.95, respectively.
- Analytical standard for research and analytical applications
- Potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent
- 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS