Piperidines

Organic heterocyclic compounds that consist of a six-membered ring containing five carbon atoms and one nitrogen atom that forms an amine functional group.

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1,666 – 1,680 of 2,118 results

1,666

Medchemexpress LLC 2-piperidone (δ-valerolactam) | 675-20-7 | MFCD00006037 | 99.9% | 99.13 | C5H9NO | 50 G

2-Piperidone is a small-molecule endogenous metabolite reported as a biomarker for CYP2E1 activity. It is used in biochemical and metabolic research where measurement or modulation of metabolic enzyme activity is required.

chemical formula: C5H9NO
molecular weight: 99.13 g/mol
cas number: 675-20-7
high purity (reported): 99.9%
available in multiple pack sizes, including 50 G
soluble in common organic solvents; supplied as DMSO solution options for ready use
storage: pure form at -20°C (long-term) or 4°C (shorter-term)

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1,667

Medchemexpress LLC (-)-p-Bromotetramisole oxalate | 62284-79-1 | 99.9% | 373.22 | 50 MG

(-)-p-Bromotetramisole oxalate is an alkaline phosphatase inhibitor applicable to research related to erythroleukemia.

Inhibits terminal cell division-associated MEL DS-19 cell differentiation induced by DMSO or HMBA.
Reduces B+ cell levels.
Potently inhibits purified human liver, bone, spleen, and kidney alkaline phosphatase isoenzymes.
Minimally inhibits purified human intestinal and placental alkaline phosphatase isoenzymes.

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1,668

Biotium Lambda Light ChainICO-106 CF568 conjugate 0.1mgmL

Lambda Light ChainICO-106 CF568 conjugate 0.1mgmL

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1,669

Biotium Lambda Light ChainICO-106 CF488A conjugate 0.1mgmL

Lambda Light ChainICO-106 CF488A conjugate 0.1mgmL

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1,670

Medchemexpress LLC Bsj-03-204 | 2349356-09-6 | 99.76% | 832.90 | 100 MG

BSJ-03-204 is a PROTAC (proteolysis-targeting chimera) that connects ligands for Cereblon and CDK. It is a potent and selective Palbociclib-based CDK4/6 dual degrader, demonstrating anti-cancer activity and potent anti-proliferative effects on MCL cell lines.

Potent and selective Palbociclib-based CDK4/6 dual degrader
Does not induce IKZF1/3 degradation
Exhibits anti-cancer activity
Potent anti-proliferative effects on MCL cell lines
Induces a G1 arrest

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1,671

Medchemexpress LLC Pomalidomide-amino-PEG4-NH2 (hydrochloride) | 2331259-45-9 | 542.97 | 100 MG

Pomalidomide-amino-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. This compound is designed for use in PROTACs, which contain two different ligands connected by a linker. These PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Synthesized E3 ligase ligand-linker conjugate
Incorporates Pomalidomide based cereblon ligand
Utilizes PROTAC technology
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins

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1,672

Medchemexpress LLC BSJ-4-116 | 2519823-34-6 | 99.9% | 837.38 | 50 MG

BSJ-4-116 is a PROTAC (proteolysis-targeting chimera) designed to selectively degrade CDK12 (Cyclin-Dependent Kinase 12) with high potency, evidenced by an IC50 of 6 nM. It achieves its effect by linking ligands for Cereblon and CDK, leading to the downregulation of DNA damage response (DDR) genes through premature transcriptional termination and increased poly(adenylation). This compound exhibits significant antiproliferative capabilities, both as a standalone agent and in combination with the PARP inhibitor Olaparib. It has been shown to decrease CDK12 protein levels regardless of the cell line's mutational status and can overcome resistance due to specific CDK12 mutations.

Highly potent and selective CDK12 degrader
Downregulates DNA damage response genes
Exhibits antiproliferative effects
Can overcome resistance from specific CDK12 mutations

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1,673

Medchemexpress LLC BSJ-03-204 (triTFA) | 2349356-09-6 | 99.8% | 832.90 | 50 MG

BSJ-03-204 is a PROTAC connected by ligands for Cereblon and CDK. It is a potent and selective Palbociclib-based CDK4/6 dual degrader with anti-cancer activity, and does not induce IKZF1/3 degradation.

Potent anti-proliferative effects on MCL cell lines
Potently induces a G1 arrest
Selective degradation of CDK4/6 in WT cells

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1,674

Biotium Thyroglobulin2H11 CF568 conjugate 0.1mgmL

Thyroglobulin2H11 CF568 conjugate 0.1mgmL

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1,675

Biotium FibronectinHFN7.1 CF647 conjugate 0.1mgmL

FibronectinHFN7.1 CF647 conjugate 0.1mgmL

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1,676

Medchemexpress LLC Thalidomide-O-amido-C4-NH2 hydrochloride | 2245697-86-1 | MFCD31656719 | 98.1% | 438.86 | C19H23ClN4O6 | 25 MG

Thalidomide-O-amido-C4-NH2 hydrochloride is a thalidomide-derived E3 ligase ligand-linker conjugate supplied as a hydrochloride salt for use as an amine intermediate in the synthesis of heterobifunctional PROTACs and related degrader molecules. It combines a cereblon-binding thalidomide scaffold with a reactive terminal amine to facilitate conjugation in medicinal chemistry workflows.

Provides cereblon-binding thalidomide scaffold for E3 ligase recruitment.
Terminal primary amine suitable for conjugation to linkers or targeting ligands.
High reported purity for reliable synthetic outcomes.
Hydrochloride salt form for improved stability and handling.
Available in small mg-scale packages for research synthesis.

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1,677

Biotium TGF-beta1D11.16.8 CF770 conjugate 0.1mgmL

TGF-beta1D11.16.8 CF770 conjugate 0.1mgmL

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1,678

Biotium Thyroglobulin2H11 CF594 conjugate 0.1mgmL

Thyroglobulin2H11 CF594 conjugate 0.1mgmL

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1,679

Enzo Life Sciences Arv-825 (10mg). CAS: 1818885-28-7

ARV-825 is a PROTAC targeting on BRD4, consisting of a BRD4-ligand JQ-1 linked to a cereblon E3 ligase ligand Pomalidomide, with Kds values of 90nM and 28nM for affinity to BD1 and BD2. Purity: ≥98%. Long Term Storage: -20°C.

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1,680

Accela Chembio Inc N-boc-4-nortropinone | 25g | 185099-67-6 | MFCD00673779 | 98% | Shelf Life: 1980 Days | Regular

N-boc-4-nortropinone | 25g | 185099-67-6 | MFCD00673779 | 98% | Shelf Life: 1980 Days | Regular

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Piperidines

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Medchemexpress LLC 2-piperidone (δ-valerolactam) | 675-20-7 | MFCD00006037 | 99.9% | 99.13 | C5H9NO | 50 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (-)-p-Bromotetramisole oxalate | 62284-79-1 | 99.9% | 373.22 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bsj-03-204 | 2349356-09-6 | 99.76% | 832.90 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pomalidomide-amino-PEG4-NH2 (hydrochloride) | 2331259-45-9 | 542.97 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BSJ-4-116 | 2519823-34-6 | 99.9% | 837.38 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BSJ-03-204 (triTFA) | 2349356-09-6 | 99.8% | 832.90 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Thalidomide-O-amido-C4-NH2 hydrochloride | 2245697-86-1 | MFCD31656719 | 98.1% | 438.86 | C19H23ClN4O6 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Accela Chembio Inc N-boc-4-nortropinone | 25g | 185099-67-6 | MFCD00673779 | 98% | Shelf Life: 1980 Days | Regular Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More