Piperidines
Medchemexpress LLC Apixaban-13C,d3 (BMS-562247-01-13C,d3) | 1261393-15-0 | 99.5% | C2413CH22D3N5O4 | 1 MG
Apixaban-13C,d3 is a deuterium and 13C labeled version of Apixaban, also known as BMS-562247-01-13C,d3. Apixaban is recognized as a highly selective and reversible inhibitor of Factor Xa, demonstrating Ki values of 0.08 nM in humans and 0.17 nM in rabbits.
- Deuterium and 13C labeled compound.
- Highly selective, reversible inhibitor of Factor Xa.
- Can be used as a tracer in drug development processes.
- Suitable as an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
Medchemexpress LLC AS-99 TFA | 3115178-55-4 | 99.2% | C29H31F6N5O5S2 | 100 MG
AS-99 TFA is a first-in-class, potent, and selective ASH1L histone methyltransferase inhibitor with anti-leukemic activity. It blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo.
- Potent and selective ASH1L histone methyltransferase inhibitor
- Exhibits anti-leukemic activity
- Blocks cell proliferation
- Induces apoptosis and differentiation
- Downregulates MLL fusion target genes
- Reduces leukemia burden in vivo
- Shows over 100-fold selectivity towards ASH1L
eMolecules 98977-36-7 | 1-Boc-3-piperidone | Ambeed | MFCD01631193 | 199.250 | C10H17NO3 | 98.000 | CC(C)(C)OC(=O)N1CCCC(=O)C1 | 100g | 552668847
1-Boc-3-piperidone | Ambeed | 98977-36-7 | MFCD01631193 | 199.250 | C10H17NO3 | 98.000 | CC(C)(C)OC(=O)N1CCCC(=O)C1 | 100g | 552668847
Medchemexpress LLC BJE6-106 (B106) | 1564249-38-2 | 99.9% | 381.47 | C26H23NO2 | 10 MG
BJE6-106 (B106) is a selective protein kinase C delta (PKCδ) inhibitor supplied as a high-purity solid for research use. It induces caspase-dependent apoptosis, activates the MKK4-JNK-H2AX pathway, and shows potent activity against PKCδ with substantially lower activity versus PKCα.
- Selective PKCδ inhibition with IC50 0.05 μM.
- Induces caspase-dependent apoptosis and tumor-specific effects.
- Activates the MKK4-JNK-H2AX signaling pathway.
- High purity solid (99.85%) suitable for biochemical and cell-based assays.
- Molecular formula C26H23NO2 and molecular weight 381.47.
Enzo Life Sciences Arv-825 (5mg). CAS: 1818885-28-7
ARV-825 is a PROTAC targeting on BRD4, consisting of a BRD4-ligand JQ-1 linked to a cereblon E3 ligase ligand Pomalidomide, with Kds values of 90nM and 28nM for affinity to BD1 and BD2. Purity: ≥98%. Long Term Storage: -20°C.
Medchemexpress LLC HY-115446A 500mg Medchemexpress, Lenalidomide-C4-NH2 (hydrochloride) CAS: Purity:>98%
Medchemexpress, HY-19695 10mg (-)-p-Bromotetramisole (oxalate) CAS:62284-79-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0750B 200mg Medchemexpress, Dolasetron (Mesylate hydrate) CAS:878143-33-0 Purity:98%
Medchemexpress,HY-B0750B 200mg Dolasetron (Mesylate hydrate) CAS:878143-33-0 Formula:C20H26N2O7S Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1799711-21-9 | Medchem Express | dBET1 | 5mg | 446257250 | HY-101838 | 785.27 | C38H37ClN8O7S
Ambeed | 4-Hydroxy-2-methylpyrimidine-5-carbonitrile | 250mg | 490493564 | A110380 | 27058-54-4 | MFCD17018685 | 135.126 | C6H5N3O
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Enzo Life Sciences Arv-825 (50mg). CAS: 1818885-28-7
ARV-825 is a PROTAC targeting on BRD4, consisting of a BRD4-ligand JQ-1 linked to a cereblon E3 ligase ligand Pomalidomide, with Kds values of 90nM and 28nM for affinity to BD1 and BD2. Purity: ≥98%. Long Term Storage: -20°C.
Medchemexpress LLC HY-A0003B 100mg Medchemexpress, Lenalidomide (hemihydrate) CAS:847871-99-2 Purity:>98%
Medchemexpress, HY-A0003B 100mg Lenalidomide (hemihydrate) CAS:847871-99-2 Lenalidomide hemihydrate (CC-5013 hemihydrate) is a derivative of Thalidomide and an orally active immunomodulator. Lenalidomide hemihydrate (CC-5013 hemihydrate) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Apixaban-¹³C,d₃ | 1261393-15-0 | 99.5% | C2413CH22D3N5O4 | 5 MG
Apixaban-13C,d3 is a deuterium and 13C labeled Apixaban, a highly selective, reversible inhibitor of Factor Xa. It is suitable for use as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. This product is for research use only and not sold to patients. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules as tracers for quantitation during drug development, and deuteration may affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes for quantitation in drug development
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs