Piperidines
Medchemexpress LLC JNJ-1013 | 2597343-08-1 | C46H55N9O7S | 100 MG
JNJ-1013 is a potent and selective IRAK1 PROTAC degrader. It functions by inducing apoptosis and increasing the expression of cleaved PARP. This compound also plays a role in decreasing the expression of IRAK1, p-IKBα, and pSTAT3(Tyr705).
- Potent and selective IRAK1 PROTAC degrader
- Induces apoptosis
- Increases the expression of cleaved PARP
- Decreases the expression of IRAK1, p-IKBα, and pSTAT3(Tyr705)
eMolecules 1186663-32-0 | 4-Fluoro-4-piperidinecarboxylic Acid Hydrochloride | MFCD12198891 | 1g
ChemScene | 2-Fluoro-6-(4455-tetramethyl-132-dioxaborolan-2-yl)benzaldehyde | 100mg | 714102368 | CS-0020236 | 1246633-35-1 | MFCD18383508 | 250.080 | C13H16BFO3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Enzo Life Sciences BIX 01294 (2mg). CAS: 935693-62-2
Selective and cell permeable inhibitor of G9a histone methyltransferase. Purity: ≥95% (HPLC). Appearance: White solid. Solubility: Soluble in DMSO (5mg/ml). Long Term Storage: -20°C.
eMolecules 1184995-85-4 | 4-benzylpiperidine-4-carboxylic acid hydrochloride | MFCD12028367 | 250mg
ChemScene | Tert-butyl (5-bromopyridin-3-yl)(methyl)carbamate | 100mg | 601110339 | CS-0166585 | 1243698-95-4 | MFCD19439738 | 287.157 | C11H15BrN2O2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules 4783-65-7 | 1-Benzylpiperidin-2-one | Oakwood Chemicals | MFCD00464162 | 189.258 | C12H15NO | 98.000 | O=C1CCCCN1Cc1ccccc1 | 1g | 480163888
1-Benzylpiperidin-2-one | Oakwood Chemicals | 4783-65-7 | MFCD00464162 | 189.258 | C12H15NO | 98.000 | O=C1CCCCN1Cc1ccccc1 | 1g | 480163888
Medchemexpress LLC (S,R)-GSK321 | 1816272-18-0 | 98.6% | 501.55 g/mol | C28H28FN5O3 | 5 MG
(S,R)-GSK321 is the (S,R)-enantiomer of GSK321, a potent and selective mutant isocitrate dehydrogenase 1 (IDH1) inhibitor used as a research tool to study IDH1-driven oncogenic metabolism and differentiation. It reduces intracellular 2-hydroxyglutarate (2-HG) levels and promotes granulocytic differentiation in leukemic cells, supporting studies in acute myeloid leukemia and related cancers.
- Potent mutant IDH1 inhibitor with nanomolar activity.
- Reduces intracellular 2-hydroxyglutarate (2-HG) levels.
- Promotes granulocytic differentiation in leukemic cells.
- High purity suitable for research applications (98.6%).
- Molecular weight 501.55 g/mol; molecular formula C28H28FN5O3.
- Available in small research pack sizes, including 5 mg.
Apexbio Technology LLC Anamorelin 249921-19-5 5mg
Anamorelin (CAS 249921-19-5) is a synthetic small-molecule agonist of the growth hormone secretagogue receptor (GHSR) By binding to and activating GHSR centrally Anamorelin replicates the orexigenic and anabolic effects of endogenous ghrelin promoting appetite stimulation and growth hormone release This mechanism may also contribute to modulation of inflammatory pathways as GHSR activation is associated with reduced production of pro-inflammatory cytokines such as TNF-alpha and interleukin-6 Anamorelin is primarily investigated for its potential in studies of cancer cachexia appetite regulation and metabolic research
Medchemexpress LLC Dimethyl fumarate | 624-49-7 | 100.0% | 144.13 | 25 MG
Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator that induces upregulation of antioxidant gene expression. It induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research. It also acts as an immune modulator and inducer of the antioxidant response, suppressing HIV replication and neurotoxin release.
- Orally active and brain-penetrant Nrf2 activator
- Induces upregulation of antioxidant gene expression
- Induces necroptosis in colon cancer cells
- Induces cell autophagy
- Used for multiple sclerosis research
- Immune modulator
- Inducer of the antioxidant response
- Suppresses HIV replication and neurotoxin release
- Inhibits dendritic cell (DC) maturation
- Impairs NF-κB signaling
Aobchem 5-Bromo-3-methyl-2-(1-piperidinyl)pyridine | 95% | CAS 934000-36-9 | C11H15BrN2 | 1g
5-Bromo-3-methyl-2-(1-piperidinyl)pyridine | 95% | CAS 934000-36-9 | C11H15BrN2 | 1g
eMolecules 1312713-37-3 | 1-Boc-piperidine-3-boronic acid pinacol ester | J & W PharmLab LLC | MFCD25509459 | 311.230 | C16H30BNO4 | 96.000 | CC(C)(C)OC(=O)N1CCCC(C1)B1OC(C)(C)C(C)(C)O1 | 5g | 548147702
1-Boc-piperidine-3-boronic acid pinacol ester | J & W PharmLab LLC | 1312713-37-3 | MFCD25509459 | 311.230 | C16H30BNO4 | 96.000 | CC(C)(C)OC(=O)N1CCCC(C1)B1OC(C)(C)C(C)(C)O1 | 5g | 548147702
Medchemexpress LLC Tcn 213 | 556803-08-8 | MFCD04788042 | 99.2% | 376.54 g/mol | C18H24N4OS2 | 10 MG
TCN 213 is a research-grade, glycine-dependent GluN1/GluN2A N-methyl-D-aspartate receptor (NMDAR) antagonist supplied as a solid for biochemical and pharmacological studies. It is intended for use in receptor subtype-selectivity assays and neuropharmacology research.
- Selective, glycine-dependent GluN1/GluN2A NMDAR antagonist.
- High purity (99.2%).
- Chemical formula C18H24N4OS2 and molecular weight 376.54 g/mol.
- Available in small-milligram quantities for research use.
- Soluble in DMSO for assay preparation.
- Store protected from light at refrigerated temperatures; in solution, store at -80°C for long-term stability.
eMolecules 183673-66-7 | 1-Boc-piperidine-4-Fmoc-amino-4-carboxylic acid | ChemScene | MFCD01318741 | 466.534 | C26H30N2O6 | 98.000 | CC(C)(C)OC(=O)N1CCC(CC1)(NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 25g | 837440257
1-Boc-piperidine-4-Fmoc-amino-4-carboxylic acid | ChemScene | 183673-66-7 | MFCD01318741 | 466.534 | C26H30N2O6 | 98.000 | CC(C)(C)OC(=O)N1CCC(CC1)(NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 25g | 837440257
eMolecules 188869-05-8 | tert-Butyl 3-bromo-4-oxopiperidine-1-carboxylate | AA Blocks LLC | MFCD06738530 | 278.146 | C10H16BrNO3 | 0.000 | CC(C)(C)OC(=O)N1CCC(=O)C(Br)C1 | 25g | 433193188
tert-Butyl 3-bromo-4-oxopiperidine-1-carboxylate | AA Blocks LLC | 188869-05-8 | MFCD06738530 | 278.146 | C10H16BrNO3 | 0.000 | CC(C)(C)OC(=O)N1CCC(=O)C(Br)C1 | 25g | 433193188