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Filtered Search Results
Medchemexpress LLC K-Ras-PDE -IN-1 | 10MG
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K-Ras-PDE -IN-1 is a novel and potent competitive K-Ras-PDE inhibitor K-Ras-PDE -IN-1 binds to the farnesyl binding pocket of PDE with a low nanomolar Kd of 8 nM[1]
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Medchemexpress LLC HY-112167A 5mg Medchemexpress, GDC-0575 dihydrochloride CAS:1657014-42-0 Purity:>98%
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Medchemexpress, HY-112167A 5mg GDC-0575 diHCl CAS:1657014-42-0 GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100039 5mg Medchemexpress, YYA-021 CAS:144217-65-2 Purity:>98%
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Medchemexpress, HY-100039 5mg YYA-021 CAS:144217-65-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC B-Raf inhibitor 1 dihydrochloride 1191385-19-9 100mg
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B-Raf inhibitor 1 dihydrochloride (CAS 1191385-19-9) is a small molecule inhibitor targeting B-Raf kinase including both wild-type and mutant forms such as the V600E variant commonly found in tumor cells As a type IIA inhibitor it binds to the DFG-out conformation of the ATP-binding site on B-Raf The compound demonstrates inhibitory activity against cell proliferation with IC50 values of 0 31 M in A375 cells and 0 72 M in HCT116 cells B-Raf inhibitor 1 also inhibits other tyrosine kinases and in cells expressing wild-type B-Raf can promote activation of the RAF-MEK-ERK signaling pathway through Raf dimerization In preclinical mouse models it has been observed to induce proliferation supporting its use in studies of Raf signaling kinase inhibitor specificity and oncogenic pathway modulation
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![eMolecules 1-boc-3-azabicyclo[3.2.1]octane-8-methanol | 637301-16-7 | MFCD22566234 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502157984.JPG-250.jpg)
eMolecules 1-boc-3-azabicyclo[3.2.1]octane-8-methanol | 637301-16-7 | MFCD22566234 | 1g
Pharmablock | 1-boc-3-azabicyclo[3.2.1]octane-8-methanol | 1g | 551134382 | PBN20120314 | | 637301-16-7 | MFCD22566234 | 241.331 | C13H23NO3
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Apexbio Technology LLC SAR7334 1333210-07-3 2mg
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SAR7334 (CAS 1333210-07-3) is a small molecule inhibitor that selectively targets the transient receptor potential cation channel subfamily C member 6 (TRPC6) By inhibiting TRPC6-mediated calcium influx SAR7334 is utilized to investigate TRPC6-related signal transduction pathways in cellular and preclinical studies This compound serves as a valuable tool for elucidating the role of TRPC6 in pathophysiological processes including those related to kidney function and vascular regulation Its application aids in advancing the understanding of TRPC6-associated diseases and potential therapeutic interventions
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Medchemexpress LLC HY-18373 5mg Medchemexpress, UNC1079 CAS:1418741-86-2 Purity:>98%
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Medchemexpress, HY-18373 5mg UNC1079 CAS:1418741-86-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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![eMolecules [exo-8-azabicyclo[3.2.1]octan-3-yl]methanol;hydrochloride | 1389264-20-3 | MFCD23381619 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502156801.JPG-250.jpg)
eMolecules [exo-8-azabicyclo[3.2.1]octan-3-yl]methanol;hydrochloride | 1389264-20-3 | MFCD23381619 | 1g
Pharmablock | [exo-8-azabicyclo[3.2.1]octan-3-yl]methanol;hydrochloride | 1g | 551138612 | PBN20121082-01 | | 1389264-20-3 | MFCD23381619 | 177.670 | C8H16ClNO
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Selleck Chemical LLC YYA-021
YYA-021 is a CD4-mimic HIV entry inhibitor competitively inhibiting the interaction between gp120 and CD4
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eMolecules 2-(4-Aminopiperidin-1-yl)-n-(tert-butyl)acetamide dihydrochloride | 926224-29-5 | MFCD13857403 | 1g
Combi-Blocks | 2-(4-Aminopiperidin-1-yl)-n-(tert-butyl)acetamide dihydrochloride | 1g | 517034628 | QZ-1894 | 95.000 | 926224-29-5 | MFCD13857403 | 286.240 | C11H25Cl2N3O
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Chemscene ChemScene | Methyl 4-aminopiperidine-1-carboxylate | 1G | CS-0139158 | 0.98 | 1019351-46-2| MFCD11128922 | 158.2
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ChemScene | Methyl 4-aminopiperidine-1-carboxylate | 1G | CS-0139158 | 0.98 | 1019351-46-2| MFCD11128922 | 158.2
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Apexbio Technology LLC Copanlisib dihydrochloride 1402152-13-9 50mg
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Copanlisib dihydrochloride (CAS 1402152-13-9) is a small-molecule inhibitor that selectively targets phosphoinositide 3-kinase (PI3K) isoforms and By inhibiting these PI3K subunits copanlisib disrupts PI3K/AKT signaling pathways that regulate cellular proliferation and survival leading to reduced tumor cell growth and induction of apoptosis This compound is utilized in biomedical research to investigate PI3K-mediated oncogenic processes particularly in studies related to relapsed or refractory follicular lymphoma and other hematologic malignancies dependent on aberrant PI3K activity
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eMolecules Ambeed / Benzyl 3-aminopiperidine-1-carboxylate hydrochloride / 250mg / 552666762 / A235752 / / 960541-42-8 / MFCD04038445 / 270.760 / C13H19ClN2O2
Ambeed / Benzyl 3-aminopiperidine-1-carboxylate hydrochloride / 250mg / 552666762 / A235752 / / 960541-42-8 / MFCD04038445 / 270.760 / C13H19ClN2O2
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MSC Made in USA SSMS-250-632-N #6-32 UNC, 1/4" Length of Thread, Soft Tip Point Set Screw Nylon
Made in USA SSMS-250-632-N #6-32 UNC, 1/4" Length of Thread, Soft Tip Point Set Screw Nylon
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Apexbio Technology LLC Flupenthixol dihydrochloride 2413-38-9 10mg
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Flupenthixol dihydrochloride (CAS 2413-38-9) is a thioxanthene-derived small molecule primarily developed as an antipsychotic agent It functions as a dopamine D2 receptor antagonist modulating dopaminergic neurotransmission in the central nervous system In vitro assays demonstrate minimum inhibitory concentrations (MICs) of 10 100 g/mL against most bacterial strains with inhibitory effects observed at lower concentrations for select species including Staphylococcus aureus and Vibrio cholerae In vivo studies show that flupenthixol significantly reduces bacterial load and increases survival in murine infection models Clinically it has been evaluated for the management of schizophrenia and mood disorders supporting its utility in neuropharmacological and antimicrobial research
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