Pyrazines

TARGETMOL CHEMICALS INC AMCASERTIB 5MG

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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases. purity: 97%

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eMolecules​ 2179072-33-2 | 1-(Fluorosulfonyl)-2,3-dimethyl-1H-imidazol-3-ium trifluoromethanesulfonate | Apollo Scientific - Building Blocks328.250 | C6H8F4N2O5S2 | 0.000 | [O-]S(=O)(=O)C(F)(F)F.Cc1n(cc[n+]1C)S(F)(=O)=O | 1g | 553271353

1-(Fluorosulfonyl)-2,3-dimethyl-1H-imidazol-3-ium trifluoromethanesulfonate | Apollo Scientific - Building Blocks | 2179072-33-2328.250 | C6H8F4N2O5S2 | 0.000 | [O-]S(=O)(=O)C(F)(F)F.Cc1n(cc[n+]1C)S(F)(=O)=O | 1g | 553271353

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eMolecules​ 2179072-33-2 | 1-(Fluorosulfonyl)-2,3-dimethyl-1H-imidazol-3-ium trifluoromethanesulfonate | Combi-Blocks, Inc.328.250 | C6H8F4N2O5S2 | 96.000 | [O-]S(=O)(=O)C(F)(F)F.Cc1n(cc[n+]1C)S(F)(=O)=O | 1g | 569337975

1-(Fluorosulfonyl)-2,3-dimethyl-1H-imidazol-3-ium trifluoromethanesulfonate | Combi-Blocks, Inc. | 2179072-33-2328.250 | C6H8F4N2O5S2 | 96.000 | [O-]S(=O)(=O)C(F)(F)F.Cc1n(cc[n+]1C)S(F)(=O)=O | 1g | 569337975

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eMolecules​ 2179072-33-2 | 1-(Fluorosulfonyl)-2,3-dimethyl-1H-imidazol-3-ium trifluoromethanesulfonate | AA Blocks LLC328.250 | C6H8F4N2O5S2 | 0.000 | [O-]S(=O)(=O)C(F)(F)F.Cc1n(cc[n+]1C)S(F)(=O)=O | 25g | 796979551

1-(Fluorosulfonyl)-2,3-dimethyl-1H-imidazol-3-ium trifluoromethanesulfonate | AA Blocks LLC | 2179072-33-2328.250 | C6H8F4N2O5S2 | 0.000 | [O-]S(=O)(=O)C(F)(F)F.Cc1n(cc[n+]1C)S(F)(=O)=O | 25g | 796979551

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Medchemexpress LLC Methyl 3-aminopropanoate hydrochloride | 3196-73-4 | 139.58 | 1 ML

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Methyl 3-aminopropanoate hydrochloride is a compound prepared by the esterification of Β-Alanine (I).

• Used in the synthesis of bidentate pyridine-acid ligands.
• Suitable for proteomics research.

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Medchemexpress LLC 5,6-Diamino-1,10-phenanthroline | 168646-54-6 | 210.23 | 500 MG

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5,6-Diamino-1,10-phenanthroline can be used as ligands for metal ions for drug synthesis. It is intended for research use only, and not sold to patients.

• Used as ligands for metal ions for drug synthesis
• Appearance: solid
• Color: yellow to orange
• Solid storage: 4°C, protected from light, stored under nitrogen
• Solvent storage: -80°C for 6 months, or -20°C for 1 month (protected from light, stored under nitrogen)

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Apexbio Technology LLC SCR7 pyrazine 14892-97-8 5mg

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SCR7 pyrazine (CAS 14892-97-8) is a small-molecule inhibitor of DNA ligase IV a critical enzyme in the nonhomologous end-joining (NHEJ) pathway responsible for repairing DNA double-strand breaks (DSBs) By disrupting the DNA binding activity of ligase IV SCR7 impedes the NHEJ-mediated repair process leading to reduced cell viability and increased apoptosis In cellular assays SCR7 demonstrated dose-dependent inhibition of proliferation in various cancer cell lines with reported IC50 values ranging from 8 5 to 120 M Additionally in mouse models SCR7 administration suppressed tumor growth and enhanced sensitivity to DSB-inducing therapies highlighting its utility for studying DNA repair mechanisms and potential as an adjunct in cancer research

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eMolecules​ 2417-73-4 | Methyl 2-bromomethylbenzoate | Ambeed | MFCD03425900 | 229.073 | C9H9BrO2 | 95.000 | COC(=O)c1ccccc1CBr | 100g | 490552203

Methyl 2-bromomethylbenzoate | Ambeed | 2417-73-4 | MFCD03425900 | 229.073 | C9H9BrO2 | 95.000 | COC(=O)c1ccccc1CBr | 100g | 490552203

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TARGETMOL CHEMICALS INC CRONIDIPINE 5MG

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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Cronidipine (LF 20254) a calcium channel antagonist is used potentially for the treatment of hypertension and myocardia ischemia. purity: 99%

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TARGETMOL CHEMICALS INC Research Chemical 25mg

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Also available in 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. 2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription. purity: 99%

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TARGETMOL CHEMICALS INC SAPANISERTIB 25MG

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Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sapanisertib (INK 128) is an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity. purity: 99%

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eMolecules​ 98006-90-7 | 2-Bromo-5-methylpyrazine | ChemScene | MFCD08705754 | 173.013 | C5H5BrN2 | 96.000 | Cc1cnc(Br)cn1 | 1g | 572270981

2-Bromo-5-methylpyrazine | ChemScene | 98006-90-7 | MFCD08705754 | 173.013 | C5H5BrN2 | 96.000 | Cc1cnc(Br)cn1 | 1g | 572270981

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Medchemexpress LLC 5-Bromo-2,4-diamino-6-hydroxypyrimidine | 6312-72-7 | 205.01 | 250 MG

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5-Bromo-2,4-diamino-6-hydroxypyrimidine is a biochemical reagent intended for research use only. It is not sold to patients.

• Suitable for biochemical assay research
• Available in various pack sizes
• Supported by a data sheet and handling instructions

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Medchemexpress LLC Pyrazine | 290-37-9 | 99.97% | 80.09 | 100 G

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Pyrazine is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, known for its electron-deficient property. It serves as a key pharmacophore in various drugs and acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic, and anti-inflammatory activities.

• Key pharmacophore in various drugs
• Core skeleton for derivatives with anticancer, antimycobacterial, antithrombotic, and anti-inflammatory activities
• Undergoes Chichibabin reaction to form 2-aminopyrazine
• Reacts with H2O2/CH3COOH to form mono and dioxide products
• Can be synthesized via catalytic dehydrogenation of ethanolamine
• Monobasic compound with a pKa of 0.65

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TARGETMOL CHEMICALS INC NEOBAVAISOFLAVONE 5MG

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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity can significantly inhibit the production of reactive oxygen species (ROS) reactive nitrogen species (RNS) and cytokines IL-1(beta) IL-6 IL-12p4 IL-12p7 TNF-(alpha) in LPS+IFN-(gamma)- or PMA- stimulated RAW264.7 macrophages. purity: 99%

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