Pyridines and derivatives
- (4)
- (1)
- (5)
- (5)
- (520)
- (22)
- (2,105)
- (22)
- (2)
- (5)
- (5)
- (271)
- (175)
- (1)
- (14)
- (50)
- (300)
- (86)
- (225)
- (6)
- (4)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (12)
- (4)
- (8)
- (7)
- (12)
- (60)
- (867)
- (5)
- (55)
- (60)
- (58)
- (19)
- (346)
- (2)
- (4)
- (2)
- (1)
- (1)
- (5)
- (275)
- (1)
- (1,700)
- (2)
- (27)
- (7)
- (1)
- (92)
- (4)
- (13)
- (77)
- (128)
- (54)
- (59)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
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- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (9)
- (4)
- (1)
- (2)
- (4)
- (2)
- (1)
- (5)
- (17)
- (23)
- (1)
- (1)
- (60)
- (21)
- (1)
- (1)
- (29)
- (49)
- (7)
- (2)
- (1)
- (5)
- (6)
- (12)
- (1)
- (1)
- (1)
- (18)
- (1)
- (14)
- (4)
- (1)
- (11)
- (5)
- (1)
- (10)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (9)
- (7)
- (1)
- (2)
- (1)
- (4)
- (6)
- (2)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (1)
- (5)
- (15)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (12)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (15)
- (17)
- (4)
- (2)
- (2)
- (5)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (7)
- (5)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (16)
- (7)
- (5)
- (1)
- (1)
- (3)
- (5)
- (10)
- (2)
- (1)
- (6)
- (6)
- (7)
- (12)
- (1)
- (1)
- (39)
- (1)
- (12)
- (11)
- (4)
- (2)
- (2)
- (15)
- (15)
- (1)
- (1)
- (1)
- (2)
- (9)
- (3)
- (2)
- (1)
- (1)
- (3)
- (6)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (6)
- (5)
- (2)
- (1)
- (19)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (22)
- (22)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (22)
- (16)
- (6)
- (2)
- (1)
- (1)
- (2)
- (7)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
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- (17)
- (2)
- (1)
- (6)
- (1)
- (3)
- (1)
- (2)
- (1)
- (6)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (6)
- (2)
- (3)
- (3)
- (3)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (5)
- (3)
- (1)
- (4)
- (12)
- (48)
- (1)
- (4)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (7)
- (9)
- (22)
- (30)
- (1)
- (1)
- (3)
- (2)
- (2)
- (4)
- (11)
- (5)
- (1)
- (1)
- (55)
- (6)
- (1)
- (7)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
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- (1)
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- (1)
- (2)
- (6)
- (4)
- (15)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
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- (1)
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- (9)
- (1)
- (1)
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- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
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- (13)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (10)
- (23)
- (1)
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- (2)
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- (1)
- (1)
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- (6)
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- (1)
- (1)
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- (11)
- (3)
- (2)
- (1)
- (1)
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- (1)
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- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (34)
- (3)
- (4)
- (4)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (5)
- (3)
- (5)
- (8)
- (4)
- (2)
- (1)
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- (1)
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- (2)
- (3)
- (1)
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- (18)
- (1)
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- (1)
- (1)
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- (1)
- (3)
- (1)
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- (11)
- (18)
- (1)
- (1)
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- (1)
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- (8)
- (6)
- (2)
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- (1)
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- (11)
- (2)
- (2)
- (2)
- (4)
- (1)
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- (5)
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- (2)
- (1)
- (2)
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- (1)
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- (1)
- (1)
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- (8)
- (1)
- (1)
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- (4)
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- (2)
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- (1)
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- (2)
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- (1)
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- (53)
- (1)
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- (1)
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- (33)
- (6)
- (1)
- (1)
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- (1)
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- (544)
- (5)
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- (42)
- (22)
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- (9)
- (1)
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- (1)
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- (1)
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- (1)
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- (3)
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- (1,015)
- (4)
- (2)
- (1)
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- (12)
- (904)
- (7)
- (35)
- (7)
- (2)
- (1)
- (418)
- (26)
- (4)
- (10)
- (1)
- (1)
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- (1)
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- (2)
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- (1)
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- (1)
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- (2)
- (8)
- (72)
- (4)
- (1,561)
- (2)
- (4)
- (12)
- (9)
- (1)
- (14)
- (3)
- (9)
- (3)
- (2)
- (5)
- (4)
- (2)
- (1)
- (16)
- (3)
- (13)
- (11)
- (13)
- (10)
- (2)
- (2)
- (1)
- (2)
- (2)
- (408)
- (5)
- (6)
- (2)
- (7)
- (2)
- (3)
- (2)
- (237)
- (3)
- (2)
- (3)
- (18)
- (5)
- (2)
- (264)
- (3)
- (4)
- (4)
- (1)
- (2)
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- (1)
- (2)
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- (2)
- (2)
- (2)
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- (2)
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- (1)
- (1)
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- (1)
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- (1)
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![Medchemexpress LLC 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one | 504433-23-2 | 99.85% | 275.30 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387661-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one | 504433-23-2 | 99.85% | 275.30 | 5 MG
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GW 441756 is identified as a potent and specific inhibitor of nerve growth factor (NGF) receptor tyrosine kinase A (TrkA), with an IC50 of 2 nM. It has been shown to eliminate BmK NSPK-induced neurite outgrowth.
- Potent and specific nerve growth factor (NGF) receptor tyrosine kinases A (TrkA) inhibitor (IC50=2 nM).
- Eliminates BmK NSPK-induced neurite outgrowth.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Selleck Chemical LLC MG149
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MG149 (Tip60 HAT inhibitor) is a potent histone acetyltransferase inhibitor with IC50 of 74 M and 47 M for Tip60 and MOF respectively
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BIOHIPPO T3RE-TAL-BSD LV
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T3RE-TAL-BSD is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a blasticidin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
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Aobchem AOBCHEM
5000930364 2- 3-BROMO-2-ISOPROPOXY-5-ISOP
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BIOHIPPO hPDGFD-sh-GFP-Puro
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hPDGFD-sh-GFP-Puro shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human Each vial provides a nominal titer of 5x10E6 transducing units TU Validated human PDGFD shRNA Lentivirus High-titer shRNA lentiviral particles specific for human platelet derived growth factor D (PDGFD) The shRNA has been validated to meet or exceed 70% PDGFD knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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Sigma Aldrich Fine Chemicals Biosciences Sera MagTM SpeedBeadsTM Bl
Sera-Mag(TM) SpeedBeads(TM) and Sera-Mag(TM) Carboxylate-Modified Magnetic Particles combine a fast magnetic response time and high binding capacity with a large surface area high sensitivity stability physical integrity and fast reaction kinetics. Covalent coupling of biomolecules such as proteins and nucleic acids to carboxyl groups on the surface is easily accomplished using our standard coupling technology. The core of the particle is made by a free radical emulsion polymerization of styrene and acid monomer. One (Sera-Mag(TM)) or two (Sera-Mag(TM) SpeedBeads(TM)) layers of magnetite are then coated onto this core while the surface is modified to minimize non-specific binding of proteins.
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Aobchem AOBCHEM
5000930409 2- 3-BROMO-2-ISOPROPOXY-5-ISOP
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Medchemexpress LLC Cenicriviroc | 497223-25-3 | 98.1% | 696.94 | 1 ML
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Cenicriviroc is an orally active compound that functions as a dual antagonist of CCR2 and CCR5. Its biological activity includes the inhibition of both HIV-1 and HIV-2. Furthermore, it exhibits potent anti-inflammatory and antiinfective properties, indicating its potential application in treating conditions related to these activities.
- Orally active.
- Dual antagonist of CCR2/CCR5.
- Inhibits HIV-1 and HIV-2.
- Potent anti-inflammatory activity.
- Potent antiinfective activity.
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Selleck Chemical LLC Plixorafenib
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Plixorafenib (PLX8394) is a next-generation orally available small-molecule BRAF inhibitor with IC50 values of 3 8 nM 14 nM and 23 nM for BRAF(V600E) WT BRAF and CRAF respectively It has potential antineoplastic activity
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Selleck Chemical LLC IDO-IN-2
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IDO-IN-2 (RG 6078 NLG-919 analogue GDC-0919 analogue) is a a potent IDO1 inhibitor with IC50 of 38 nM
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Accela Chembio Inc 3-bromo-2-chloropyridine | 100g | 52200-48-3 | MFCD00234007 | 97+% | Shelf Life: 1620 Days | Light Sensitive
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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3-bromo-2-chloropyridine | 100g | 52200-48-3 | MFCD00234007 | 97+% | Shelf Life: 1620 Days | Light Sensitive
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Chem-Impex International, Inc. 3,5-Dichloropyridine | MFCD00006376 | 25G
3,5-Dichloropyridine, MFCD00006376, 25G
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Selleck Chemical LLC XL888
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XL888 is an ATP-competitive inhibitor of HSP90 with IC50 of 24 nM Phase 1
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Medchemexpress LLC Cenicriviroc Mesylate | 497223-28-6 | 99.9% | 793.05 | 25 MG
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Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist that inhibits both HIV-1 and HIV-2. It exhibits potent anti-inflammatory and antiinfective activity, making it suitable for various research applications.
- Dual CCR2/CCR5 antagonist
- Inhibits HIV-1 and HIV-2
- Potent anti-inflammatory activity
- Potent antiinfective activity
- Active in cellular models (IC50 for CCR5: 0.29 nM, CCR2: 5.9 nM)
- Reduces monocyte/macrophage recruitment in vivo
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Medchemexpress LLC Eglu | 170984-72-2 | 99.8% | 175.18 | C7H13NO4 | 1 MG
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EGLU ((2S)-α-ethylglutamic acid) is a selective, competitive antagonist of metabotropic glutamate receptor 2 (mGluR2) used as a small-molecule research reagent in neuropharmacology. Supplied as a purified solid for laboratory research applications.
- Selective mGluR2 antagonist for receptor pharmacology studies.
- High purity (99.8%) for reliable experimental results.
- Molecular formula C7H13NO4 and molecular weight 175.18.
- Available in milligram-scale quantities suitable for small-scale assays.
- Characterized solid with supporting datasheet and safety information.
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