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Filtered Search Results
Medchemexpress LLC Br-PEG7-Br | 177987-04-1 | 98.0% | 496.23 | 1 G
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Br-PEG7-Br is a chemical compound with a molecular weight of 496.23 and a CAS number of 177987-04-1. It is intended for laboratory use and manufacture of substances.
- Identified uses include laboratory chemicals and manufacture of substances
- High purity of 98.0%
- Stable under recommended storage conditions
- Colorless to light yellow liquid appearance
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules BR-PEG2-CH2COOTBU 1G
5000165378 BR-PEG2-CH2COOTBU 1G
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Medchemexpress LLC M-PEG4-BR 500MG
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5000202136 M-PEG4-BR 500MG
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Medchemexpress LLC m-PEG8-Br | 100MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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m-PEG8-Br | 100MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules BR-PEG2-CH2COOTBU 5G
5000163770 BR-PEG2-CH2COOTBU 5G
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Apexbio Technology LLC 5-Br-CTP 10ul (100 mM)
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5-Br-CTP is a modified ribonucleoside triphosphate It is designed for use in the generation of RNA libraries via Systematic Evolution of Ligands by EXponential enrichment (SELEX) facilitating the selection of aptamers with enhanced stability Nucleic acids synthesized with 5-Br-CTP display improved resistance to nuclease degradation and increased thermal stability due to bromine substitution at the C-5 position of the cytosine base Based on these properties 5-Br-CTP holds research potential in aptamer selection and nucleic acid-based applications requiring enhanced structural integrity under stringent conditions
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Apexbio Technology LLC 5-Br-CTP 50ul (100 mM)
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5-Br-CTP is a modified ribonucleoside triphosphate It is designed for use in the generation of RNA libraries via Systematic Evolution of Ligands by EXponential enrichment (SELEX) facilitating the selection of aptamers with enhanced stability Nucleic acids synthesized with 5-Br-CTP display improved resistance to nuclease degradation and increased thermal stability due to bromine substitution at the C-5 position of the cytosine base Based on these properties 5-Br-CTP holds research potential in aptamer selection and nucleic acid-based applications requiring enhanced structural integrity under stringent conditions
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Medchemexpress LLC BR-cpd7 | 98.0% | 928.82 | 1 MG
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BR-cpd7 is a PROTAC degrader designed for fibroblast growth factor receptor FGFR1/2, exhibiting a DC50 of 10 nM. This compound has been observed to arrest the cell cycle and inhibit the proliferation of tumor cells that are aberrantly activated by FGFR1/2.
- Composed of a ligand for target protein FGFR-IN-12, a linker, and a ligand for E3 ligase Thalidomide-NH-CH2-COOH.
- Exhibits antitumor activity.
- Arrests cell cycle.
- Inhibits proliferation of FGFR1/2 aberrant activated tumor cells.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC BR-cpd7 | 98.0% | 928.82 | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BR-cpd7 is a PROTAC degrader designed to target fibroblast growth factor receptor (FGFR1/2). It has a DC50 of 10 nM and works by arresting the cell cycle and inhibiting the proliferation of FGFR1/2 aberrant activated tumor cells.
- PROTAC degrader for FGFR1/2
- DC50 of 10 nM
- Arrests cell cycle
- Inhibits proliferation of FGFR1/2 aberrant activated tumor cells
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Apexbio Technology LLC 5-Br-CTP 100ul (100 mM)
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5-Br-CTP is a modified ribonucleoside triphosphate It is designed for use in the generation of RNA libraries via Systematic Evolution of Ligands by EXponential enrichment (SELEX) facilitating the selection of aptamers with enhanced stability Nucleic acids synthesized with 5-Br-CTP display improved resistance to nuclease degradation and increased thermal stability due to bromine substitution at the C-5 position of the cytosine base Based on these properties 5-Br-CTP holds research potential in aptamer selection and nucleic acid-based applications requiring enhanced structural integrity under stringent conditions
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC BR-cpd7 | 98.0% | 928.82 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BR-cpd7 is a PROTAC degrader for fibroblast growth factor receptor FGFR1/2 with a DC50 of 10 nM. It arrests cell cycle and inhibits proliferations of FGFR1/2 aberrant activated tumor cells. The compound consists of a ligand for target protein, a linker, and a ligand for E3 ligase.
- PROTAC degrader for FGFR1/2
- Has a DC50 of 10 nM
- Arrests cell cycle
- Inhibits proliferations of FGFR1/2 aberrant activated tumor cells
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Apexbio Technology LLC 5-Br-UTP(Synonyms: 5-Bromo-UTP, 5-Br-uridine triphosphate, 5-Bromo-uridine 5'-triphosphate, 5-Br-U 5'-triphosphate), 100ul (100 mM).
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5-Br-UTP is a chemically modified ribonucleoside triphosphate that incorporates a bromine substituent at the 5 position of uracil Upon enzymatic incorporation into RNA sequences this compound confers enhanced structural stability and tolerance to enzymatic degradation by nucleases Such modified ribonucleotides are frequently employed in SELEX (Systematic Evolution of Ligands by EXponential enrichment) methodologies to generate aptamers exhibiting improved resistance to nucleolytic cleavage and greater thermal robustness Consequently 5-Br-UTP holds relevance for RNA-based therapeutic research and aptamer engineering applications
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Medchemexpress LLC Br-cpd7 | 98.0% | 928.82 | C44H47Cl2N11O8 | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BR-cpd7 is a PROTAC degrader targeting fibroblast growth factor receptors FGFR1 and FGFR2, exhibiting a DC50 of 10 nM. It arrests the cell cycle and inhibits proliferation in cells with aberrant FGFR1/2 activation. The compound is supplied as a solid powder for research use.
- Targets FGFR1 and FGFR2 with a DC50 of 10 nM.
- High purity (98.01%) suitable for research applications.
- Available in small milligram pack sizes, including 10 MG.
- Soluble in DMSO at 100 mg/mL; may require ultrasonic treatment.
- Powder stable at -20°C for up to 3 years; solvent stability varies by condition.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC M-PEG12-Br | 1620461-89-3 | C25H51BrO12 | 1 G
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m-PEG12-Br is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These molecules are designed to exploit the intracellular ubiquitin-proteasome system, selectively degrading target proteins. PROTACs feature two distinct ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other targets a specific protein, making m-PEG12-Br a key component in this targeted protein degradation strategy.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Connects ligands for E3 ubiquitin ligase and target protein
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Br-PEG4-OH | 85141-94-2 | 98.2% | 1 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Br-PEG4-OH is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins by linking a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- PEG-based PROTAC linker.
- Utilized in the synthesis of PROTACs.
- Facilitates the selective degradation of target proteins.
- Exploits the ubiquitin-proteasome system.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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