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Filtered Search Results
Medchemexpress LLC 2,3,4,5-Tetracaffeoyl-D-Glucaric acid | 1419478-52-6 | 5 MG
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2,3,4,5-Tetracaffeoyl-D-Glucaric acid is a caffeoyl-D-glucaric acid derivative isolated from the Genus Gnaphalium, intended for research use only.
- Isolated from the genus Gnaphalium
- Purity of 99.29%
- Molecular weight of 858.71
- Formula: C42H34O20
- Appears as an off-white to light yellow solid
- Initial source includes various plants
- Classified as phenylpropanoid
- Soluble in DMSO at 100 mg/mL
- Used in inflammation/immunology research
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Medchemexpress LLC LP-261 | 915412-67-8 | 99.9% | C22H19N3O4S | 50 MG
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LP-261 is a potent, orally active anti-mitotic agent that inhibits tubulin polymerization in vitro with an EC50 of 3.2 μM. It has shown the ability to inhibit the growth of human non-small-cell lung tumors (NCI-H522) in vivo and is used in cancer research.
- Potent and orally active anti-mitotic agent.
- Inhibits tubulin polymerization in vitro.
- Shows potent G2/M block activity in various cell lines (MCF-7, H522, Jurkat, SW-620, BXPC-3, and PC-3) with IC50 values ranging from 0.01 μM to 0.38 μM.
- Effectively inhibits tumor growth in a human non-small-cell lung tumor xenograft model in NCr-nu mice, with a 96% reduction in mean tumor volume at 50 mg/kg.
- Displays rapid oral adsorption with a Tmax of 2.0 hours in rats.
- Exhibits moderate elimination rate with a terminal half-life of 1.4 hours in rats.
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eMolecules AstaTech / 4-O-TOLYLPIPERIDINE / 0.25g / 268503647 / BL008747 / 95.000 / 630116-52-8 / MFCD05189913 / 175.275 / C12H17N
AstaTech / 4-O-TOLYLPIPERIDINE / 0.25g / 268503647 / BL008747 / 95.000 / 630116-52-8 / MFCD05189913 / 175.275 / C12H17N
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![eMolecules Pharmablock / [3-(trifluoromethyl)-1-bicyclo[1.1.1]pentanyl]methanaminehydrochloride / 25mg / 714320303 / PB93851-1 / 0.000 / 1886967-52-7 / [null] / 201.620 / C7H11ClF3N](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502461570.JPG-250.jpg)
eMolecules Pharmablock / [3-(trifluoromethyl)-1-bicyclo[1.1.1]pentanyl]methanaminehydrochloride / 25mg / 714320303 / PB93851-1 / 0.000 / 1886967-52-7 / [null] / 201.620 / C7H11ClF3N
Pharmablock / [3-(trifluoromethyl)-1-bicyclo[1.1.1]pentanyl]methanaminehydrochloride / 25mg / 714320303 / PB93851-1 / 0.000 / 1886967-52-7 / [null] / 201.620 / C7H11ClF3N
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eMolecules ChemScene / Inhoffen Lythgoe diol / 100mg / 572223546 / CS-M0511 / 0.000 / 64190-52-9 / MFCD00144484 / 212.333 / C13H24O2
ChemScene / Inhoffen Lythgoe diol / 100mg / 572223546 / CS-M0511 / 0.000 / 64190-52-9 / MFCD00144484 / 212.333 / C13H24O2
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Medchemexpress LLC GDC-0310 | 1788063-52-4 | 98.8% | 543.48 | 50 MG
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GDC-0310 is a selective acyl-sulfonamide Nav1.7 inhibitor, demonstrating an IC50 of 0.6 nM for hNav1.7. It exhibits an EC50 of 1.1 μM in vivo and a Ki of 1.8 nM for Nav1.7, showcasing improved Nav selectivity and ADME properties.
- Selective acyl-sulfonamide Nav1.7 inhibitor
- IC50 of 0.6 nM for hNav1.7
- EC50 of 1.1 μM in vivo
- Ki of 1.8 nM for Nav1.7
- Improved Nav selectivity and ADME properties
- Exhibits t1/2 values of 5 h in rat, 46 h in dog, and 4.4 h in cynomolgus monkeys
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Medchemexpress LLC Ssaa09e2 | 883944-52-3 | 98.4% | 300.36 | 100 MG
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SSAA09E2 is an inhibitor of SARS-CoV (Severe acute respiratory syndrome-Coronavirus) replication. It acts by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2).
- Inhibitor of SARS-CoV replication
- Blocks early interactions of SARS-S with ACE2 receptor
- Molecular formula: C16H20N4O2
- Molecular weight: 300.36
- Purity: 98.4%
- Appearance: Solid
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Medchemexpress LLC Pralnacasan | 192755-52-5 | MFCD18381953 | 99.8% | 523.54 g·mol⁻1 | C26H29N5O7 | 10 MG
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Pralnacasan is a potent, selective, orally active inhibitor of interleukin-1β converting enzyme (caspase-1) used in preclinical inflammation and apoptosis research. It is supplied as a high-purity white to off-white powder with defined solubility and storage recommendations for in vitro and in vivo studies.
- High potency with Ki of 1.4 nM against caspase-1.
- High purity (99.8%) suitable for research applications.
- Supplied as a white to off-white solid powder for easy handling.
- Highly soluble in DMSO (220 mg/mL) for stock preparation.
- Formulation protocols available for in vivo dosing to achieve clear solutions.
- Stable when stored as powder at -20°C for extended periods.
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Medchemexpress LLC ArnicolideC | 34532-67-7 | 5 MG
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ArnicolideC is a sesquiterpene lactone isolated from *Centipeda minima*. It demonstrates a cytotoxic effect on nasopharyngeal carcinoma (NPC) cells, significantly inhibiting cell growth in a dose- and time-dependent manner and exhibiting inhibitory effects on NPC proliferation.
- Molecular weight: 334.41
- Formula: C₁₉H₂₆O₅
- Appearance: Solid, white to off-white
- Structure classification: Terpenoids, sesquiterpenes
- Purity: 99.81%
- Isolated from *Centipeda minima*
- Cytotoxic effect on nasopharyngeal carcinoma (NPC) cells
- Inhibits cell growth in a dose- and time-dependent manner
- Inhibits NPC proliferation
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Bioworld Cytosine, 25 g
It is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached. The nucleoside of cytosine is cytidine. In Watson-Crick base pairing, it forms three hydrogen bonds with guanine.Specifications:Ultra Pure GradeEm (275 nm, 0.1M HCl): >9,900 Appearance: White SolidChEBI : Not available.Crystal_Structure : Not available.Density : 0.48 g/cm3InChI : Not available.InChIKey : Not available.Melting Point: >300 °CRTECS Number: UW7350150
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Medchemexpress LLC Kukoamine B | 164991-67-7 | MFCD29904539 | 99.9% | 530.66 g/mol | C28H42N4O6 | 10 MG
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Kukoamine B is a spermine alkaloid supplied as a high-purity research chemical that acts as a dual inhibitor of lipopolysaccharide (LPS) and CpG DNA for biochemical and cellular studies.
- Dual inhibitor of LPS and CpG DNA.
- High purity (~99.9%) suitable for analytical and biological assays.
- Available in small research pack sizes, including 10 MG powder and 10 mM solutions.
- Molecular formula C28H42N4O6; molecular weight 530.66 g/mol.
- Used in anti-inflammatory, antioxidant, and metabolic research applications.
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![Medchemexpress LLC Anthra[1,2-c]thiadiazole-6,11-dione | 4219-52-7 | 98.0% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000233929.png-250.jpg)
Medchemexpress LLC Anthra[1,2-c]thiadiazole-6,11-dione | 4219-52-7 | 98.0% | 50 MG
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NSC745885 (anthra[1,2-c]thiadiazole-6,11-dione) is a small-molecule anti-tumor research compound supplied as a solid powder with high purity for in vitro and preclinical studies.
- Small-molecule anti-tumor scaffold (anthra[1,2-c]thiadiazole-6,11-dione).
- CAS 4219-52-7.
- Purity 98.0%.
- Molecular formula C14H6N2O2S; molecular weight 266.27 g/mol.
- Solid powder; available in 5 mg-100 mg sizes.
- Storage: powder stable at -20°C for long-term; in solvent store at -80°C for short-term.
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Cambridge Isotope Laboratories URACIL (5-D, 98%), 0.25 G, 24897-50-5
URACIL (5-D, 98%), 0.25 G, 24897-50-5
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Medchemexpress LLC 5,6-Dihydro-5-methyluracil | 696-04-8 | 50 MG
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5,6-Dihydro-5-methyluracil (Dihydrothymine) is an intermediate breakdown product of thymine, found in animals or plants. It can be toxic at abnormally high levels.
- Endogenous metabolite
- Molecular weight: 128.13
- Formula: C5H8N2O2
- Appearance: Solid
- Color: White to off-white
- Initial source: Endogenous metabolite, human gut microbiota metabolites
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture
- In solvent storage: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
- Purity: 99.88%
- Chemical structure: O=C1NC(C(C)CN1)=O
- Structure classification: Others
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eMolecules Medchem Express / GSK-J2 / 10mg / 446266239 / HY-15648A / / 1394854-52-4 / MFCD27991274 / 389.459 / C22H23N5O2
Medchem Express / GSK-J2 / 10mg / 446266239 / HY-15648A / / 1394854-52-4 / MFCD27991274 / 389.459 / C22H23N5O2
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