Pyrimidines And Derivatives
![4-Chlorobenzofuro[3,2-d]pyrimidine 98.0+%, TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-39876-88-5.jpg-250.jpg)
4-Chlorobenzofuro[3,2-d]pyrimidine 98.0+%, TCI America™
CAS: 39876-88-5 Molecular Formula: C10H5ClN2O Molecular Weight (g/mol): 204.613 MDL Number: MFCD00763943 InChI Key: ABRHSRPOYMSBOI-UHFFFAOYSA-N PubChem CID: 609295 IUPAC Name: 4-chloro-[1]benzofuro[3,2-d]pyrimidine SMILES: C1=CC=C2C(=C1)C3=C(O2)C(=NC=N3)Cl
Medchemexpress LLC Amiprofos methyl (BAY-NTN 6867) | 36001-88-4 | 99.4% | 304.30 | 25 MG
Amiprofos methyl is a phosphoric amide herbicide. It is a specific and potent antimicrotubule agent that directly poisons microtubule dynamics in plant cells.
- Phosphoric amide herbicide
- Specific and potent antimicrotubule agent
- Directly poisons microtubule dynamics in plant cells
Medchemexpress LLC Ethanone, 1-(6-amino-2-naphthalenyl)- | 7470-88-4 | 99.6% | 185.23 | 250 MG
1-(6-Aminonaphthalen-2-yl)ethan-1-one is a chemical compound primarily used as a drug intermediate. It plays a crucial role in the synthesis of various active compounds, offering versatility in chemical development.
- Serves as a drug intermediate
- Enables synthesis of active compounds
![Chemscene ChemScene | 4-Chlorobenzofuro[3,2-d]pyrimidine | 1G | CS-W018725 | 0.98 | 39876-88-5| MFCD00763943 | 204.62](https://assets.fishersci.com/TFS-Assets/CCG/product-images/CS-W018725.jpg-250.jpg)
Chemscene ChemScene | 4-Chlorobenzofuro[3,2-d]pyrimidine | 1G | CS-W018725 | 0.98 | 39876-88-5| MFCD00763943 | 204.62
ChemScene | 4-Chlorobenzofuro[3,2-d]pyrimidine | 1G | CS-W018725 | 0.98 | 39876-88-5| MFCD00763943 | 204.62
![Medchemexpress LLC 5,7-dichloro-[1,3]thiazolo[5,4-d]pyrimidine | 13479-88-4 | MFCD09702027 | ≥98.0% | 206.05 g/mol | C5HCl2N3S | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000302375.png-250.jpg)
Medchemexpress LLC 5,7-dichloro-[1,3]thiazolo[5,4-d]pyrimidine | 13479-88-4 | MFCD09702027 | ≥98.0% | 206.05 g/mol | C5HCl2N3S | 250 MG
5,7-Dichlorothiazolo[5,4-d]pyrimidine (CAS 13479-88-4) is a chlorinated heterocyclic building block used as an intermediate in small-molecule and medicinal chemistry synthesis. It is supplied in research-scale quantities and is offered by chemical suppliers in defined purity grades for use in route scouting and heterocycle construction.
- Used as a synthetic building block for heterocycle construction and medicinal chemistry.
- Molecular formula C5HCl2N3S and molecular weight 206.05 g/mol.
- CAS number 13479-88-4 for unambiguous identification.
- Offered in small pack sizes suitable for research (50 mg-500 mg).
- Available in high-purity grades (reported ≥98% by some suppliers).
- Supplied with standard documentation such as COA and SDS for quality verification.
eMolecules 87573-88-4 | 1-(2-HYDROXYPYRIMIDIN-5-YL)ETHANONE | AstaTech | MFCD29921801 | 138.126 | C6H6N2O2 | 95.000 | CC(=O)c1cnc(O)nc1 | 1g | 384830342
1-(2-HYDROXYPYRIMIDIN-5-YL)ETHANONE | AstaTech | 87573-88-4 | MFCD29921801 | 138.126 | C6H6N2O2 | 95.000 | CC(=O)c1cnc(O)nc1 | 1g | 384830342
eMolecules 34374-88-4 | 2,4,6-Triformylphloroglucinol | ChemScene | MFCD24713435 | 210.141 | C9H6O6 | 97.000 | Oc1c(C=O)c(O)c(C=O)c(O)c1C=O | 250mg | 559783626
2,4,6-Triformylphloroglucinol | ChemScene | 34374-88-4 | MFCD24713435 | 210.141 | C9H6O6 | 97.000 | Oc1c(C=O)c(O)c(C=O)c(O)c1C=O | 250mg | 559783626
![Medchemexpress LLC 3-(2-methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid | 1233706-88-1 | MFCD18206878 | >98.0% | 471.5 | C28H25NO6 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239672.png-250.jpg)
Medchemexpress LLC 3-(2-methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid | 1233706-88-1 | MFCD18206878 | >98.0% | 471.5 | C28H25NO6 | 25 MG
CAY10650 is a potent and selective cytosolic phospholipase A2α (cPLA2α) inhibitor (IC50 = 12 nM) used to study inflammatory signaling and the synthesis of arachidonic acid-derived mediators. The compound is characterized by formula C28H25NO6, molecular weight 471.5, and is supplied at high purity for research use.
- Inhibits cPLA2α with low nanomolar potency (IC50 = 12 nM).
- Suppresses lipid droplet formation and PGE2 secretion in cellular assays.
- Shows topical anti-inflammatory effects in mouse models.
- Provided at ≥98% purity for research applications.
- Suitable for studies of prostaglandin and leukotriene biosynthesis.
Medchemexpress LLC HY-10115A 100mg , PI-103 (Hydrochloride) CAS:371935-79-4 Purity:98%
Medchemexpress, HY-10115A 100mg PI-103 (Hydrochloride) CAS:371935-79-4 Formula:C19H17ClN4O3 IC50: 8 nM (p110α), 88 nM (p110β), 48 nM (p110δ), 150 nM (p110γ), 2 nM (DNA-PK), 20 nM (mTORC1), 83 nM (mTORC2), 26 nM (PI3KC2β), 850 nM (ATR), 920 nM (ATM), ~1 μM (PI3KC2α), 2.3 μM (hsVPS34), ~50 μM (PI4KIIIβ) Purity:98% PI-103 Hydrochloride is a potent PI3K and mTOR inhibitor with IC 50 s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α , p110β , p110δ , p110γ , mTORC1 , and mTORC2 . PI-103 also inhibits DNA-PK with an IC50 of 2 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-10115A 5mg Medchemexpress, PI-103 (Hydrochloride) CAS:371935-79-4 Purity:>98%
Medchemexpress, HY-10115A 5mg PI-103 (Hydrochloride) CAS:371935-79-4 PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC 50 s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α , p110β , p110δ , p110γ , mTORC1 , and mTORC2 . PI-103 also inhibits DNA-PK with an IC50 of 2 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Regorafenib monohydrate 1019206-88-2 10mM (in 1mL DMSO)
Regorafenib monohydrate (CAS 1019206-88-2) is a multitargeted tyrosine kinase inhibitor that suppresses numerous intracellular and membrane receptor tyrosine kinases (RTKs) including VEGFR (types 1-3) PDGFR- FGFR-1 RET TIE2 c-KIT Raf-1 and BRAF (wild-type and V600E mutant) It inhibits angiogenic RTKs such as VEGFR-2 with IC50 values ranging from approximately 4 2 to 46 nM and oncogenic RTKs like c-KIT and RET with IC50 values around 1 5 to 28 nM Regorafenib demonstrates antiproliferative activity in vitro (mean IC50 1 M) and reduces tumor progression in xenograft animal models supporting its use in cancer research involving breast colorectal thyroid pancreatic cancers melanoma and gastrointestinal stromal tumors
Apexbio Technology LLC Regorafenib monohydrate 1019206-88-2 100mg
Regorafenib monohydrate (CAS 1019206-88-2) is a multitargeted tyrosine kinase inhibitor that suppresses numerous intracellular and membrane receptor tyrosine kinases (RTKs) including VEGFR (types 1-3) PDGFR- FGFR-1 RET TIE2 c-KIT Raf-1 and BRAF (wild-type and V600E mutant) It inhibits angiogenic RTKs such as VEGFR-2 with IC50 values ranging from approximately 4 2 to 46 nM and oncogenic RTKs like c-KIT and RET with IC50 values around 1 5 to 28 nM Regorafenib demonstrates antiproliferative activity in vitro (mean IC50 1 M) and reduces tumor progression in xenograft animal models supporting its use in cancer research involving breast colorectal thyroid pancreatic cancers melanoma and gastrointestinal stromal tumors
Methyl 5-bromoorotate, 97%, Thermo Scientific™
CAS: 30825-88-8 Molecular Formula: C6H5BrN2O4 Molecular Weight (g/mol): 249.02 MDL Number: MFCD07023034 InChI Key: UJCPEPQYSPRWGU-UHFFFAOYSA-N Synonym: methyl 5-bromo-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate,methyl 5-bromo-2,6-dioxo-1,3-dihydropyrimidine-4-carboxylate,methyl 5-bromo-2,6-dihydroxypyrimidine-4-carboxylate,4-pyrimidinecarboxylic acid, 5-bromo-1,2,3,6-tetrahydro-2,6-dioxo-, methyl ester PubChem CID: 6324367 IUPAC Name: methyl 5-bromo-2,4-dioxo-1H-pyrimidine-6-carboxylate SMILES: COC(=O)C1=C(C(=O)NC(=O)N1)Br