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Pyrimidines And Derivatives

Aromatic organic compounds that consist of an aromatic six-membered ring containing two non-adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyrimidines.
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1

4-Chlorobenzofuro[3,2-d]pyrimidine 98.0+%, TCI America™

CAS: 39876-88-5 Molecular Formula: C10H5ClN2O Molecular Weight (g/mol): 204.613 MDL Number: MFCD00763943 InChI Key: ABRHSRPOYMSBOI-UHFFFAOYSA-N PubChem CID: 609295 IUPAC Name: 4-chloro-[1]benzofuro[3,2-d]pyrimidine SMILES: C1=CC=C2C(=C1)C3=C(O2)C(=NC=N3)Cl

PubChem CID 609295
CAS 39876-88-5
Molecular Weight (g/mol) 204.613
MDL Number MFCD00763943
SMILES C1=CC=C2C(=C1)C3=C(O2)C(=NC=N3)Cl
IUPAC Name 4-chloro-[1]benzofuro[3,2-d]pyrimidine
InChI Key ABRHSRPOYMSBOI-UHFFFAOYSA-N
Molecular Formula C10H5ClN2O
2

eMolecules​ 1-(2-HYDROXYPYRIMIDIN-5-YL)ETHANONE | 87573-88-4 | MFCD29921801 | 1g

AstaTech | 1-(2-HYDROXYPYRIMIDIN-5-YL)ETHANONE | 1g | 384830342 | F13147 | 95.000 | 87573-88-4 | MFCD29921801 | 138.126 | C6H6N2O2

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3

Medchemexpress LLC Amiprofos methyl (BAY-NTN 6867) | 36001-88-4 | 99.4% | 304.30 | 25 MG
SDP

Amiprofos methyl is a phosphoric amide herbicide. It is a specific and potent antimicrotubule agent that directly poisons microtubule dynamics in plant cells.

  • Phosphoric amide herbicide
  • Specific and potent antimicrotubule agent
  • Directly poisons microtubule dynamics in plant cells

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4

Medchemexpress LLC Ethanone, 1-(6-amino-2-naphthalenyl)- | 7470-88-4 | 99.6% | 185.23 | 250 MG
SDP

1-(6-Aminonaphthalen-2-yl)ethan-1-one is a chemical compound primarily used as a drug intermediate. It plays a crucial role in the synthesis of various active compounds, offering versatility in chemical development.

  • Serves as a drug intermediate
  • Enables synthesis of active compounds

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5

eMolecules​ ChemScene 2 4 6-Triformylphloroglucinol 250mg 559783626 CS-W023142 0 000 34374-88-4 MFCD24713435 210 141 C9H6O6

ChemScene 2 4 6-Triformylphloroglucinol 250mg 559783626 CS-W023142 0 000 34374-88-4 MFCD24713435 210 141 C9H6O6

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6

Chemscene ChemScene | 4-Chlorobenzofuro[3,2-d]pyrimidine | 1G | CS-W018725 | 0.98 | 39876-88-5| MFCD00763943 | 204.62
SDP

ChemScene | 4-Chlorobenzofuro[3,2-d]pyrimidine | 1G | CS-W018725 | 0.98 | 39876-88-5| MFCD00763943 | 204.62

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7

Medchemexpress LLC 5,7-dichloro-[1,3]thiazolo[5,4-d]pyrimidine | 13479-88-4 | MFCD09702027 | ≥98.0% | 206.05 g/mol | C5HCl2N3S | 250 MG
SDP

5,7-Dichlorothiazolo[5,4-d]pyrimidine (CAS 13479-88-4) is a chlorinated heterocyclic building block used as an intermediate in small-molecule and medicinal chemistry synthesis. It is supplied in research-scale quantities and is offered by chemical suppliers in defined purity grades for use in route scouting and heterocycle construction.

  • Used as a synthetic building block for heterocycle construction and medicinal chemistry.
  • Molecular formula C5HCl2N3S and molecular weight 206.05 g/mol.
  • CAS number 13479-88-4 for unambiguous identification.
  • Offered in small pack sizes suitable for research (50 mg-500 mg).
  • Available in high-purity grades (reported ≥98% by some suppliers).
  • Supplied with standard documentation such as COA and SDS for quality verification.

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8

Medchemexpress LLC 3-(2-methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid | 1233706-88-1 | MFCD18206878 | >98.0% | 471.5 | C28H25NO6 | 25 MG
SDP

CAY10650 is a potent and selective cytosolic phospholipase A2α (cPLA2α) inhibitor (IC50 = 12 nM) used to study inflammatory signaling and the synthesis of arachidonic acid-derived mediators. The compound is characterized by formula C28H25NO6, molecular weight 471.5, and is supplied at high purity for research use.

  • Inhibits cPLA2α with low nanomolar potency (IC50 = 12 nM).
  • Suppresses lipid droplet formation and PGE2 secretion in cellular assays.
  • Shows topical anti-inflammatory effects in mouse models.
  • Provided at ≥98% purity for research applications.
  • Suitable for studies of prostaglandin and leukotriene biosynthesis.

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9

Medchemexpress LLC HY-10115A 100mg , PI-103 (Hydrochloride) CAS:371935-79-4 Purity:98%
SDP

Medchemexpress, HY-10115A 100mg PI-103 (Hydrochloride) CAS:371935-79-4 Formula:C19H17ClN4O3 IC50: 8 nM (p110α), 88 nM (p110β), 48 nM (p110δ), 150 nM (p110γ), 2 nM (DNA-PK), 20 nM (mTORC1), 83 nM (mTORC2), 26 nM (PI3KC2β), 850 nM (ATR), 920 nM (ATM), ~1 μM (PI3KC2α), 2.3 μM (hsVPS34), ~50 μM (PI4KIIIβ) Purity:98% PI-103 Hydrochloride is a potent PI3K and mTOR inhibitor with IC 50 s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α , p110β , p110δ , p110γ , mTORC1 , and mTORC2 . PI-103 also inhibits DNA-PK with an IC50 of 2 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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10

Medchemexpress LLC HY-10115A 5mg Medchemexpress, PI-103 (Hydrochloride) CAS:371935-79-4 Purity:>98%
SDP

Medchemexpress, HY-10115A 5mg PI-103 (Hydrochloride) CAS:371935-79-4 PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC 50 s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α , p110β , p110δ , p110γ , mTORC1 , and mTORC2 . PI-103 also inhibits DNA-PK with an IC50 of 2 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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11

Apexbio Technology LLC Regorafenib monohydrate 1019206-88-2 10mM (in 1mL DMSO)
SDP

Regorafenib monohydrate (CAS 1019206-88-2) is a multitargeted tyrosine kinase inhibitor that suppresses numerous intracellular and membrane receptor tyrosine kinases (RTKs) including VEGFR (types 1-3) PDGFR- FGFR-1 RET TIE2 c-KIT Raf-1 and BRAF (wild-type and V600E mutant) It inhibits angiogenic RTKs such as VEGFR-2 with IC50 values ranging from approximately 4 2 to 46 nM and oncogenic RTKs like c-KIT and RET with IC50 values around 1 5 to 28 nM Regorafenib demonstrates antiproliferative activity in vitro (mean IC50 1 M) and reduces tumor progression in xenograft animal models supporting its use in cancer research involving breast colorectal thyroid pancreatic cancers melanoma and gastrointestinal stromal tumors

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12

Apexbio Technology LLC Regorafenib monohydrate 1019206-88-2 100mg
SDP

Regorafenib monohydrate (CAS 1019206-88-2) is a multitargeted tyrosine kinase inhibitor that suppresses numerous intracellular and membrane receptor tyrosine kinases (RTKs) including VEGFR (types 1-3) PDGFR- FGFR-1 RET TIE2 c-KIT Raf-1 and BRAF (wild-type and V600E mutant) It inhibits angiogenic RTKs such as VEGFR-2 with IC50 values ranging from approximately 4 2 to 46 nM and oncogenic RTKs like c-KIT and RET with IC50 values around 1 5 to 28 nM Regorafenib demonstrates antiproliferative activity in vitro (mean IC50 1 M) and reduces tumor progression in xenograft animal models supporting its use in cancer research involving breast colorectal thyroid pancreatic cancers melanoma and gastrointestinal stromal tumors

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