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Pyrimidines And Derivatives

Aromatic organic compounds that consist of an aromatic six-membered ring containing two non-adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyrimidines.
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1

4-Chlorobenzofuro[3,2-d]pyrimidine 98.0+%, TCI America™

CAS: 39876-88-5 Molecular Formula: C10H5ClN2O Molecular Weight (g/mol): 204.613 MDL Number: MFCD00763943 InChI Key: ABRHSRPOYMSBOI-UHFFFAOYSA-N PubChem CID: 609295 IUPAC Name: 4-chloro-[1]benzofuro[3,2-d]pyrimidine SMILES: C1=CC=C2C(=C1)C3=C(O2)C(=NC=N3)Cl

PubChem CID 609295
CAS 39876-88-5
Molecular Weight (g/mol) 204.613
MDL Number MFCD00763943
SMILES C1=CC=C2C(=C1)C3=C(O2)C(=NC=N3)Cl
IUPAC Name 4-chloro-[1]benzofuro[3,2-d]pyrimidine
InChI Key ABRHSRPOYMSBOI-UHFFFAOYSA-N
Molecular Formula C10H5ClN2O
2

Medchemexpress LLC L-Selenocystine | 29621-88-3 | 98.0% | 250 MG
SDP

L-Selenocystine is a selenium-containing amino acid known for its redox properties. It demonstrates cytotoxic effects on various tumor cells, promoting the production of reactive oxygen species (ROS) and apoptosis. This compound also has the ability to inhibit the Nrf2 and autophagy pathways, contributing to its anti-tumor activity.

  • Selenium-containing amino acid
  • Exhibits redox properties
  • Cytotoxic to various tumor cells
  • Induces ROS production and apoptosis
  • Blocks Nrf2 and autophagy pathways
  • Demonstrates anti-tumor activity
  • Inhibits proliferation of HepG2 cells
  • Modulates apoptosis-related proteins

ENCOMPASS_PREFERRED
3

eMolecules​ Synthonix Tris(3-hydroxypropyltriazolylmethyl)amine 250mg 865783470 T73581 0 000 760952-88-3 MFCD27665386 434 505 C18H30N10O3

Synthonix Tris(3-hydroxypropyltriazolylmethyl)amine 250mg 865783470 T73581 0 000 760952-88-3 MFCD27665386 434 505 C18H30N10O3

ENCOMPASS_PREFERRED
4

eMolecules​ Pharmablock 3 3-difluorocyclobutan-1-ol 250mg 551330774 PBN20121035 0 000 637031-88-0 MFCD18791191 108 088 C4H6F2O

Pharmablock 3 3-difluorocyclobutan-1-ol 250mg 551330774 PBN20121035 0 000 637031-88-0 MFCD18791191 108 088 C4H6F2O

ENCOMPASS_PREFERRED
5

Medchemexpress LLC (R)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate | 1146954-88-2 | MFCD18071557 | 97.0% | 233.26 | C10H19NO5 | 10 G
SDP

(R)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate is the R-enantiomer of a Boc-protected serine ethyl ester used as a protected amino acid building block in synthetic and medicinal chemistry. Supplied as a solid for research use, it enables incorporation of protected serine residues in peptide synthesis and small-molecule routes.

  • R-enantiomer for stereospecific synthesis.
  • Boc-protected amino group for orthogonal protection.
  • Ethyl ester provides protected carboxyl functionality.
  • High purity (97.0%) suitable for research applications.
  • Solid, white to off-white form for easy handling.
  • Storage stability: powder stable at -20°C and 4°C for extended periods.
  • Documentation available: datasheet, COA, and SDS.

ENCOMPASS_PREFERRED
6

Medchemexpress LLC (R)-ethyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate | 1146954-88-2 | MFCD18071557 | 97.0% | 233.26 g/mol | C10H19NO5 | 100 G
SDP

(R)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate is the R-enantiomer of an N-Boc protected serine ethyl ester used as a synthetic intermediate in organic and peptide chemistry. It serves as a stereochemically defined building block for incorporation of protected serine residues and for selective functionalization in multi-step syntheses.

  • R-configured N-Boc protected serine ethyl ester.
  • Useful intermediate for peptide synthesis and amino acid derivatization.
  • High purity suitable for research applications.
  • Protected hydroxyl and amino groups allow selective transformations.
  • Compatible with common coupling and deprotection protocols.

ENCOMPASS_PREFERRED
7

Medchemexpress LLC (R)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate | 1146954-88-2 | MFCD18071557 | 97.0% | 233.26 g/mol | C10H19NO5 | 25 G
SDP

(R)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate is the R-enantiomer of a Boc-protected serine ethyl ester, intended as a building block for peptide synthesis and small-molecule assembly. It is supplied as a powder with specified purity and storage recommendations for research use.

  • Enantiomerically pure R-configuration.
  • Boc-protected amino acid derivative for peptide and organic synthesis.
  • High reported purity: 97.0%.
  • Offered in multiple sizes for lab-scale flexibility.
  • Recommended storage preserves stability and shelf life.

ENCOMPASS_PREFERRED
8

eMolecules​ Combi-Blocks Inc 3-Methoxypropanal 250mg 767152684 JP-4146 90 000 2806-84-0 MFCD08704314 88 106 C4H8O2

Combi-Blocks Inc 3-Methoxypropanal 250mg 767152684 JP-4146 90 000 2806-84-0 MFCD08704314 88 106 C4H8O2

ENCOMPASS_PREFERRED
9

Medchemexpress LLC 3-(2-methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid | 1233706-88-1 | MFCD18206878 | >98.0% | 471.5 | C28H25NO6 | 25 MG
SDP

CAY10650 is a potent and selective cytosolic phospholipase A2α (cPLA2α) inhibitor (IC50 = 12 nM) used to study inflammatory signaling and the synthesis of arachidonic acid-derived mediators. The compound is characterized by formula C28H25NO6, molecular weight 471.5, and is supplied at high purity for research use.

  • Inhibits cPLA2α with low nanomolar potency (IC50 = 12 nM).
  • Suppresses lipid droplet formation and PGE2 secretion in cellular assays.
  • Shows topical anti-inflammatory effects in mouse models.
  • Provided at ≥98% purity for research applications.
  • Suitable for studies of prostaglandin and leukotriene biosynthesis.

ENCOMPASS_PREFERRED
10

Apexbio Technology LLC Regorafenib monohydrate 1019206-88-2 100mg
SDP

Regorafenib monohydrate (CAS 1019206-88-2) is a multitargeted tyrosine kinase inhibitor that suppresses numerous intracellular and membrane receptor tyrosine kinases (RTKs) including VEGFR (types 1-3) PDGFR- FGFR-1 RET TIE2 c-KIT Raf-1 and BRAF (wild-type and V600E mutant) It inhibits angiogenic RTKs such as VEGFR-2 with IC50 values ranging from approximately 4 2 to 46 nM and oncogenic RTKs like c-KIT and RET with IC50 values around 1 5 to 28 nM Regorafenib demonstrates antiproliferative activity in vitro (mean IC50 1 M) and reduces tumor progression in xenograft animal models supporting its use in cancer research involving breast colorectal thyroid pancreatic cancers melanoma and gastrointestinal stromal tumors

ENCOMPASS_PREFERRED
11

Apexbio Technology LLC Regorafenib monohydrate 1019206-88-2 10mM (in 1mL DMSO)
SDP

Regorafenib monohydrate (CAS 1019206-88-2) is a multitargeted tyrosine kinase inhibitor that suppresses numerous intracellular and membrane receptor tyrosine kinases (RTKs) including VEGFR (types 1-3) PDGFR- FGFR-1 RET TIE2 c-KIT Raf-1 and BRAF (wild-type and V600E mutant) It inhibits angiogenic RTKs such as VEGFR-2 with IC50 values ranging from approximately 4 2 to 46 nM and oncogenic RTKs like c-KIT and RET with IC50 values around 1 5 to 28 nM Regorafenib demonstrates antiproliferative activity in vitro (mean IC50 1 M) and reduces tumor progression in xenograft animal models supporting its use in cancer research involving breast colorectal thyroid pancreatic cancers melanoma and gastrointestinal stromal tumors

ENCOMPASS_PREFERRED