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Pyrimidines And Derivatives

Aromatic organic compounds that consist of an aromatic six-membered ring containing two non-adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyrimidines.
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Ethyl uracil-5-carboxylate, 98%

CAS: 28485-17-8 Molecular Formula: C7H8N2O4 Molecular Weight (g/mol): 184.15 MDL Number: MFCD00057337 InChI Key: MKNYHTGOVKPZMU-UHFFFAOYSA-N Synonym: 5-carbethoxyuracil,ethyl4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate,ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate,isoorotic acid ethyl ester,ethyl 2,4-dihydroxypyrimidine-5-carboxylate,ethyl uracil-5-carboxylate,ethyl 1,2,3,4-tetrahydro-2,4-dioxopyrimidine-5-carboxylate,5-pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, ethyl ester,ethyl 2,4-dioxo-1,3-dihydropyrimidine-5-carboxylate,pubchem13254 PubChem CID: 101411 IUPAC Name: ethyl 2,4-dioxo-1H-pyrimidine-5-carboxylate SMILES: CCOC(=O)C1=CNC(=O)NC1=O

PubChem CID 101411
CAS 28485-17-8
Molecular Weight (g/mol) 184.15
MDL Number MFCD00057337
SMILES CCOC(=O)C1=CNC(=O)NC1=O
Synonym 5-carbethoxyuracil,ethyl4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate,ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate,isoorotic acid ethyl ester,ethyl 2,4-dihydroxypyrimidine-5-carboxylate,ethyl uracil-5-carboxylate,ethyl 1,2,3,4-tetrahydro-2,4-dioxopyrimidine-5-carboxylate,5-pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, ethyl ester,ethyl 2,4-dioxo-1,3-dihydropyrimidine-5-carboxylate,pubchem13254
IUPAC Name ethyl 2,4-dioxo-1H-pyrimidine-5-carboxylate
InChI Key MKNYHTGOVKPZMU-UHFFFAOYSA-N
Molecular Formula C7H8N2O4
2
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Thermo Scientific Chemicals Thiamine hydrochloride, 98.5-101.5%

CAS: 67-03-8 Molecular Formula: C12H17ClN4OS·HCl Molecular Weight (g/mol): 337.26 MDL Number: MFCD00012780 InChI Key: DPJRMOMPQZCRJU-UHFFFAOYSA-M Synonym: thiamine hydrochloride,vitamin b1 hydrochloride,thiamine hcl,aneurine hydrochloride,berin,thiamine chloride hydrochloride,trophite,thiamin chloride,thiamine dichloride,thiaminium chloride PubChem CID: 6202 ChEBI: CHEBI:49105 IUPAC Name: 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol;chloride;hydrochloride SMILES: CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.Cl.[Cl-]

PubChem CID 6202
CAS 67-03-8
Molecular Weight (g/mol) 337.26
ChEBI CHEBI:49105
MDL Number MFCD00012780
SMILES CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.Cl.[Cl-]
Synonym thiamine hydrochloride,vitamin b1 hydrochloride,thiamine hcl,aneurine hydrochloride,berin,thiamine chloride hydrochloride,trophite,thiamin chloride,thiamine dichloride,thiaminium chloride
IUPAC Name 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol;chloride;hydrochloride
InChI Key DPJRMOMPQZCRJU-UHFFFAOYSA-M
Molecular Formula C12H17ClN4OS·HCl
3

Medchemexpress LLC Flumethasone | 2135-17-3 | 99.8% | 250 MG
SDP

Flumethasone (Flumetasone) is an orally active, highly selective and potent glucocorticoid receptor (GR) agonist. It activates GR to inhibit nuclear factor kappa B (NF-κB)-mediated pro-inflammatory cytokine production (TNF-α, IL-1β) and promotes anti-inflammatory gene expression (IL-10). It also regulates metabolic enzyme activity, such as tyrosine aminotransferase induction. Flumethasone shows promise for research into inflammatory diseases, cancer, and endocrine regulation.

  • Orally active
  • High selective and potent glucocorticoid receptor (GR) agonist
  • Inhibits NF-κB-mediated pro-inflammatory cytokine production (TNF-α, IL-1β)
  • Promotes anti-inflammatory gene expression (IL-10)
  • Regulates metabolic enzyme activity (tyrosine aminotransferase induction)
  • Promising for research of inflammatory diseases, cancer, and endocrine regulation

ENCOMPASS_PREFERRED
4

Medchemexpress LLC BAM 15 | 210302-17-3 | 99.8% | 340.29 | 250 MG
SDP

BAM 15 is a mitochondrial protonophore uncoupler and an oxidative phosphorylation (OXPHOS) uncoupler. It offers several benefits for research applications.

  • Increases O2 consumption without increasing reactive oxygen species.
  • Maintains uncoupled respiration at high rates across a broad concentration range.
  • Fully increases mitochondrial respiration in the presence of oligomycin.
  • Induces mitochondrial swelling.
  • Treated cells are more viable than FCCP-treated cells across a broad dosing range.
  • Protects from kidney injury in vivo, reducing tubular necrosis and immune cell infiltration.

ENCOMPASS_PREFERRED
5

Medchemexpress LLC 9-Hydroxyphenanthrene | 484-17-3 | 98.6% | 194.23 | 250 MG
SDP

9-Phenanthrol (9-Hydroxyphenanthrene) is a selective TRPM4 inhibitor with an IC50 of 17 μM. It demonstrates no inhibitory activity on TRPM5, TRPC6, and CFTR. This compound can be utilized for research into ischemia-reperfusion injury, with studies showing it can reduce myocardial dysfunction in isolated rat hearts subjected to ischemia and reperfusion.

  • Selective TRPM4 inhibitor with an IC50 of 17 μM.
  • Shows no inhibitory activity on TRPM5, TRPC6, and CFTR.
  • Useful for research into ischemia-reperfusion injury.
  • Can reduce myocardial dysfunction in isolated rat hearts.
  • Leads to significant improvement in heart function.
  • Reduces infarct size in affected hearts.

ENCOMPASS_PREFERRED
6

Aobchem 1-Mesitylcyclobutanol | 95% | CAS 2085331-17-3 | C13H18O | 250mg

1-Mesitylcyclobutanol | 95% | CAS 2085331-17-3 | C13H18O | 250mg

ENCOMPASS_PREFERRED
7

Medchemexpress LLC N-succinimidyl 3-(2-pyridyldithio)propionate | 68181-17-9 | MFCD00009636 | 99.1% | 312.37 g/mol | C12H12N2O4S2 | 250 MG
SDP

SPDP is a short-chain, heterobifunctional crosslinker (N-succinimidyl 3-(2-pyridyldithio)propionate) that contains an NHS ester and a pyridyldithiol group. It enables formation of a cleavable disulfide linkage between primary amines and sulfhydryls, making it suitable for reversible bioconjugation, protein labeling, and linker applications requiring reduction-sensitive release.

  • Enables amine-to-sulfhydryl conjugation via NHS ester and pyridyldithiol.
  • Forms cleavable disulfide bonds reducible by intracellular glutathione.
  • Short spacer arm minimizes steric interference in conjugates.
  • Suitable for antibody-drug conjugates and reversible protein labeling.
  • Provided as a high-purity solid for biochemical reactions.

ENCOMPASS_PREFERRED
8

eMolecules​ 68181-17-9 | N-Succinimidyl 3-(2-pyridyldithio)propionate | Chemodex Ltd. | MFCD00009636 | 312.360 | C12H12N2O4S2 | 97.000 | O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O | 25mg | 849672892

N-Succinimidyl 3-(2-pyridyldithio)propionate | Chemodex Ltd. | 68181-17-9 | MFCD00009636 | 312.360 | C12H12N2O4S2 | 97.000 | O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O | 25mg | 849672892

ENCOMPASS_PREFERRED
9

eMolecules​ 68181-17-9 | N-Succinimidyl 3-(2-Pyridyldithio)propionate | Combi-Blocks | MFCD00009636 | 312.360 | C12H12N2O4S2 | 96.000 | O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O | 1g | 415501514

N-Succinimidyl 3-(2-Pyridyldithio)propionate | Combi-Blocks | 68181-17-9 | MFCD00009636 | 312.360 | C12H12N2O4S2 | 96.000 | O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O | 1g | 415501514

ENCOMPASS_PREFERRED
10

Selleck Chemical LLC Ethyl Vanillate S3993-25mg

Ethyl vanillin (Bourbonal Ethylprotal) a vanillin analog is a flavouring agent and a fungicidal agent that exhibits strong antioxidant activity Ethyl Vanillate inhibits 17 -HSD2 with an IC50 1 3 M

ENCOMPASS_PREFERRED
11

Research Products International Corp Imipenem Monohydrate 100 MG
SDP

  • CAS Number: 74431-23-5
  • Molecular Formula: C12H17N3O4S • H2O
  • Molecular Weight: 317.36

ENCOMPASS_PREFERRED
12

eMolecules​ 3438-61-7 | 5-Amino-4-methylpyrimidine | MFCD09038780 | 1g

ChemScene | 25-Dichloro-6-methylnicotinonitrile | 100mg | 717420927 | CS-0527939 | 84703-17-3 | MFCD16877636 | 187.020 | C7H4Cl2N2

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ENCOMPASS_PREFERRED
13

Medchemexpress LLC 17-hydroxyheptadecanoic acid | 13099-34-8 | MFCD00506157 | 99.7% | 286.45 g/mol | C17H34O3 | 250MG
SDP

17-hydroxyheptadecanoic acid is a 17-carbon ω-hydroxy fatty acid supplied as a white to off-white solid intended for research use in lipid metabolism studies and analytical workflows. The material is accompanied by a batch certificate of analysis reporting 99.70% purity (HPLC), and includes molecular formula C17H34O3 and molecular weight 286.45 g/mol. Recommended storage: room temperature for the solid (up to 3 years); in solvent store at -80°C (2 years) or -20°C (1 year).

  • High purity suitable for analytical and research applications.
  • Batch certificate of analysis available for traceable quality.
  • Solid form is convenient for weighing and storage.
  • Storage conditions specified for solid and solvent forms.
  • Molecular formula and molecular weight provided for method development.
  • CAS number 13099-34-8 enables precise identification.

ENCOMPASS_PREFERRED
14

5-Carbethoxyuracil, 98%, Thermo Scientific™

CAS: 28485-17-8 Molecular Formula: C7H8N2O4 Molecular Weight (g/mol): 184.15 MDL Number: MFCD00057337 InChI Key: MKNYHTGOVKPZMU-UHFFFAOYSA-N Synonym: 5-carbethoxyuracil,ethyl4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate,ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate,isoorotic acid ethyl ester,ethyl 2,4-dihydroxypyrimidine-5-carboxylate,ethyl uracil-5-carboxylate,ethyl 1,2,3,4-tetrahydro-2,4-dioxopyrimidine-5-carboxylate,5-pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, ethyl ester,ethyl 2,4-dioxo-1,3-dihydropyrimidine-5-carboxylate,pubchem13254 PubChem CID: 101411 IUPAC Name: ethyl 2,4-dioxo-1H-pyrimidine-5-carboxylate SMILES: CCOC(=O)C1=CNC(=O)NC1=O

PubChem CID 101411
CAS 28485-17-8
Molecular Weight (g/mol) 184.15
MDL Number MFCD00057337
SMILES CCOC(=O)C1=CNC(=O)NC1=O
Synonym 5-carbethoxyuracil,ethyl4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate,ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate,isoorotic acid ethyl ester,ethyl 2,4-dihydroxypyrimidine-5-carboxylate,ethyl uracil-5-carboxylate,ethyl 1,2,3,4-tetrahydro-2,4-dioxopyrimidine-5-carboxylate,5-pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, ethyl ester,ethyl 2,4-dioxo-1,3-dihydropyrimidine-5-carboxylate,pubchem13254
IUPAC Name ethyl 2,4-dioxo-1H-pyrimidine-5-carboxylate
InChI Key MKNYHTGOVKPZMU-UHFFFAOYSA-N
Molecular Formula C7H8N2O4