Pyrroles
Medchemexpress LLC (-)-Corey lactone diol | 32233-40-2 | 172.18 | 5 G
(-)-Corey lactone diol is the reduced form of Corey aldehyde. It is used as a drug intermediate for the synthesis of Beraprost.
- Drug intermediate
- Chiral building block
- Used in the synthesis of prostaglandin analogue Beraprost
- Relevant for inflammation or immune system disease research
- Relevant for blood or cardio-cerebrovascular disease research
Selleck Chemical LLC Atorvastatin Calcium S2077-500mg
Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol Atorvastatin Calcium induces apoptosis and autophagy
Apexbio Technology LLC Almotriptan Malate 181183-52-8 100mg
Almotriptan Malate (CAS 181183-52-8) is a small molecule belonging to the triptan class acting as a selective agonist at 5-hydroxytryptamine 1B/1D (5-HT1B/1D) receptors By stimulating these receptors Almotriptan modulates cranial vasoconstriction and inhibits the release of pro-inflammatory neuropeptides biologically counteracting migraine pathophysiology In research applications Almotriptan Malate is utilized to investigate serotonergic signaling pathways migraine mechanisms and the pharmacodynamics of 5-HT1B/1D receptor modulation in neurological models
Medchemexpress LLC N-Desethyl Sunitinib | 356068-97-8 | 99.9% | 370.42 | 100 MG
N-Desethyl Sunitinib (SU-12662) is a metabolite of Sunitinib. It serves as a good transport substrate for human ABCB1, ABCG2, and murine ABCG2. It is for research use only.
- Good transport substrate for human ABCB1, ABCG2, and murine ABCG2.
- Effective against K562 cells.
- Provided as a solid.
Medchemexpress LLC Sunitinib impurity 28 | 1186651-51-3 | 98.5% | 299.31 | 100 MG
Sunitinib impurity 28 is a chemical substance intended for research use only and is not suitable for human or therapeutic use. It has a CAS Number of 1186651-51-3 and a molecular weight of 299.31.
- High purity of 98.50%
- Reliable product for research purposes
- Available in 100 MG quantity
Medchemexpress LLC Massoia lactone | 54814-64-1 | 25 G
Massoia lactone is a coconut and creamy fragrant compound primarily isolated from Cryptocarya massoy. It is also known as a fragrant biosurfactant produced by the fungus Aureobasidium pullulans.
- Coconut and creamy fragrant compound
- Primarily isolated from Cryptocarya massoy
- Functions as a fragrant biosurfactant
- Produced by Aureobasidium pullulans
- Molecular weight: 168.23
- Chemical formula: C10H16O2
- Appearance: Liquid
- Color: Light yellow to light brown
- Purity: 98.75%
- Storage (pure form): -20°C for 3 years
Medchemexpress LLC HY-15816A 5mg Medchemexpress, Ulixertinib (hydrochloride) CAS:1956366-10-1 Purity:>98%
Medchemexpress, HY-15816A 5mg Ulixertinib (hydrochloride) CAS:1956366-10-1 Ulixertinib hydrochloride is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC 50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Pizotifen Malate 5189-11-7 500mg
Pizotifen malate (CAS 5189-11-7) is a benzocycloheptane derivative that functions as a potent antagonist of serotonin (5-HT) receptors exhibiting high selectivity for this target class By inhibiting serotonergic neurotransmission Pizotifen malate is utilized in biomedical research to investigate the physiological and pharmacological roles of 5-HT pathways Its receptor blocking properties enable studies focused on serotonergic modulation migraine mechanisms and disorders associated with altered serotonin signaling
Medchemexpress LLC Atorvastatin hemicalcium | 134523-03-8 | 99.94% | 577.67 | 1 ML
Atorvastatin hemicalcium salt (CI-981) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. It is capable of penetrating the blood-brain barrier and effectively reduces blood lipids. This compound inhibits human SV-SMC proliferation and invasion, and decreases apoptosis of myocardial cells by down-regulating specific proteins. It also activates endoplasmic reticulum (ER) stress in response to heart failure and angiotensin II (Ang II) stimulation. This product is for research use only.
- Orally active HMG-CoA reductase inhibitor
- Penetrates the blood-brain barrier
- Effectively reduces blood lipids
- Inhibits human SV-SMC proliferation and invasion
- Decreases myocardial cell apoptosis
- Activates endoplasmic reticulum (ER) stress response
- Reduces ER stress signaling proteins
- Inhibits proinflammatory cytokines
Medchemexpress LLC (-)-Corey lactone diol | 32233-40-2 | 172.18 | 10 G
(-)-Corey lactone diol is the reduced form of Corey aldehyde, serving as a versatile drug intermediate. It is commonly used in the synthesis of compounds such as Beraprost.
- Reduced form of Corey aldehyde
- Used as a drug intermediate for synthesis
- Appears as a solid
- Purity 98.0%
- White to off-white appearance
- Stable under recommended storage conditions
- For research use only
TARGETMOL CHEMICALS INC Sacubitril hemicalcium salt
Also available in 1 mL, 2 mg, 5 mg, 10 mg, 25 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug of LBQ657, which is an inhibitor of the zinc metallopeptidase neprilysin. Neprilysin degrades a variety of vasoactive peptides such as atrial and brain natriuretic peptide, bradykinin, adrenomedullin, and endothelin-1. Inhibition of neprilysin leads to an increased level of these peptides and, thus, antihypertensive effects. Formulations containing AHU377 in combination with the angiotensin II receptor antagonist valsartan are used to treat hypertension and heart failure. Purity 99.93%