Pyrroles
Selleck Chemical LLC BMS-986158-5mg
BMS-986158 is a potent inhibitor of BET with IC50s of 6.6 nM and 5 nM in NCI-H211 small cell lung cancer (SCLC) cells and MDA-MB231 triple negative breast cancer (TNBC) cells, respectively.
Medchemexpress LLC Tlr7 agonist 4 | 2413016-42-7 | 98.9% | C23H34N6O3 | 10MG
TLR7 agonist 4 is a small-molecule Toll-like receptor 7 (TLR7) agonist reported with an EC50 of 4.3 nM. It is supplied as a high-purity research reagent (formula C23H34N6O3, MW 442.55) intended for laboratory research use only; not for human or clinical applications.
- Potent TLR7 agonist with EC50 4.3 nM.
- High chemical purity (≈98.9%).
- Well-characterized small molecule for immunology assays.
- Solid reagent with recommended cold storage for stability.
- Includes safety data sheet for handling and hazard information.
Medchemexpress LLC BI-2852 | 2375482-51-0 | MFCD32197229 | 10 mg
BI-2852 | Purity: 98.74% | Mol Wt: 516.60 | 2375482-51-0 | MFCD32197229 | 10 mg
Medchemexpress LLC HY-112859 10mg Medchemexpress, VU0661013 CAS:2131184-57-9 Purity:>98%
Medchemexpress, HY-112859 10mg VU0661013 CAS:2131184-57-9 VU661013 is a potent and selective MCL-1 inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-103704 5mg Medchemexpress, LY2562175 CAS:1103500-20-4 Purity:>98%
Medchemexpress, HY-103704 5mg LY2562175 CAS:1103500-20-4 LY2562175 is a potent and selective FXR agonist with an EC50 of 193 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-108637 5mg Medchemexpress, PhiKan 083 CAS:880813-36-5 Purity:>98%
Medchemexpress, HY-108637 5mg PhiKan 083 CAS:880813-36-5 PhiKan 083 is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a K d of 167 μM [1] , and a relative binding affinity ( K d ) of 150 μM in Ln229 cells [3] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-18668 5mg Medchemexpress, Integrin Antagonists 27 CAS:593274-97-6 Purity:>98%
Medchemexpress, HY-18668 5mg Integrin Antagonists 27 CAS:593274-97-6 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 163769-88-8 | Medchem Express | YM-90709 | 5mg | 446270633 | HY-19969 | MFCD00354370 | 359.429 | C22H21N3O2
AstaTech | 2-(4-CHLOROPHENYL)-134-OXADIAZOLE | 1g | 449735187 | 57414 | 97.000 | 23289-10-3 | MFCD08361748 | 180.590 | C8H5ClN2O
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Medchemexpress LLC UNC2025 hydrochloride | 2070015-17-5 | 100.0% | 513.12 | C28H41ClN6O | 25MG
UNC2025 hydrochloride is the hydrochloride salt of UNC2025, a potent, ATP-competitive, orally active dual Mer (MERTK) and FLT3 kinase inhibitor used in preclinical oncology research. It exhibits sub-nanomolar potency and favorable pharmacokinetic properties, and is supplied as a light yellow solid for laboratory use.
- Potent Mer and FLT3 inhibition (IC50 0.74 nM and 0.8 nM).
- High reported purity (99.96%).
- Solid form with light yellow to yellow appearance.
- Demonstrated >45-fold selectivity for MERTK versus Axl.
- Available in multiple pack sizes and solution aliquots for flexible dosing.
- Useful as a tool compound in preclinical oncology models, including acute leukemia research.