Pyrroles
Medchemexpress LLC STING agonist-3 trihydrochloride | 98.4% | 860.19 | C37H45Cl3N12O6 | 10 MG
STING agonist-3 trihydrochloride is a selective, non-nucleotide small-molecule agonist of STING used for research in immunology and oncology. Supplied as the trihydrochloride salt in a solid, white to off-white form, it is characterized by molecular formula C37H45Cl3N12O6, molecular weight 860.19, and high purity (98.36%).
- Selective non-nucleotide STING agonist with demonstrated activity in preclinical models.
- Molecular formula C37H45Cl3N12O6; molecular weight 860.19.
- High purity (98.36%) suitable for research applications.
- Supplied as a solid; recommended dissolution in DMSO for in vitro use.
- Storage recommendations: solid at 4°C (protect from light); in solution store at -80°C for long-term.
Medchemexpress LLC HY-112898 5mg Medchemexpress, DC1SMe CAS:501666-85-9 Purity:>98%
Medchemexpress, HY-112898 5mg DC1SMe CAS:501666-85-9 DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Atorvastatin (hemicalcium trihydrate) | 344920-08-7 | 100 MG
Atorvastatin hemicalcium trihydrate is an orally active inhibitor of HMG-CoA reductase. Its primary function is to effectively lower blood lipid levels. Additionally, it has been observed to inhibit human SV-SMC proliferation and invasion, with IC50 values of 0.39 μM and 2.39 μM, respectively.
- Orally active HMG-CoA reductase inhibitor
- Effectively decreases blood lipids
- Inhibits human SV-SMC proliferation and invasion
- Demonstrates IC50s of 0.39 μM (proliferation) and 2.39 μM (invasion) in human SV-SMC
Apexbio Technology LLC Sunitinib 557795-19-4 10mM (in 1mL DMSO)
Sunitinib (CAS 557795-19-4) is an orally bioavailable small molecule inhibitor targeting multiple receptor tyrosine kinases (RTKs) including VEGFR1-3 PDGFR / c-kit and RET Research has shown sunitinib inhibits proliferation in nasopharyngeal carcinoma (NPC) cell lines HK1 CNE-1 CNE-2 HONE-1 and C666-1 with IC50 values ranging from approximately 2 06 to 7 57 M Additionally it induces apoptosis and G0/G1 cell cycle arrest in NPC cell lines and significantly decreases microvessel density in CNE-2 xenograft tumor models in vivo Thus sunitinib is useful for investigating pathways involved in tumor angiogenesis and proliferation
Medchemexpress LLC Atorvastatin sodium | 134523-01-6 | 99.9% | 580.62 | 25 MG
Atorvastatin sodium | 134523-01-6 | 99.9% | 580.62 | 25 MG
Medchemexpress LLC Pipemidic acid trihydrate | 72571-82-5 | 98.0% | 357.36 | 50 MG
Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent that inhibits DNA gyrase. It is active against gram-negative bacteria, including Pseudomonas aeruginosa, as well as some gram-positive bacteria. This compound can be used for the research of intestinal, urinary, and biliary tract infections.
- Derivative of Piromidic acid
- Antibacterial agent
- Inhibits DNA gyrase
- Active against gram-negative bacteria, including Pseudomonas aeruginosa
- Active against some gram-positive bacteria
- Can be used for research of intestinal, urinary, and biliary tract infections
Apexbio Technology LLC Dehydrocostus Lactone 477-43-0 10mM (in 1mL DMSO)
Dehydrocostus lactone is a natural sesquiterpene lactone isolated from the plant Vladimiria souliei (Franch ) Ling Chemically this compound is characterized by an -methylene- -lactone ring structure which confers bioactivity through covalent modification of nucleophilic residues in target proteins Current research explores its potential biological roles in anti-inflammatory anti-tumor and immunomodulatory contexts In pharmacological studies Dehydrocostus lactone exhibits inhibitory activity toward NF- B signaling pathways thus affecting downstream cytokine and inflammatory mediator expression Additionally this sesquiterpene lactone has been investigated in vitro for its pro-apoptotic and anti-proliferative effects in various cancer cell lines Stored under sealed cool dry laboratory conditions it represents an active compound frequently utilized in biochemical assays and biomedical investigation
Medchemexpress LLC Atorvastatin lactone | 125995-03-1 | MFCD00899262 | 96.7% | 540.62 | C33H33FN2O4 | 1 ML
Atorvastatin lactone is the lactone (prodrug) form of atorvastatin and a small-molecule HMG-CoA reductase inhibitor supplied as a ready-to-use analytical/research reagent. This product is offered as a prepared solution for biochemical assays and analytical workflows, with accompanying certificate of analysis.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- Verified purity 96.7% by HPLC.
- Molecular weight 540.62 g·mol-1 and formula C33H33FN2O4.
- Supplied with certificate of analysis.
- Storage: -80°C for up to 6 months, -20°C for up to 1 month.
- For research use only; not for human or clinical use.