Pyrroles
Medchemexpress LLC Jnj-18038683 | 851376-05-1 | 99.8% | 529.97 g/mol | C26H28ClN3O7 | 10 MG
This small-molecule research compound is a selective antagonist of the 5-hydroxytryptamine type 7 (5-HT7) receptor used in pharmacology and neuroscience studies. It shows high affinity in binding assays (pKi ≈ 8.19-8.20 for rat and human 5-HT7 in HEK293 cells), produces concentration-dependent inhibition of 5-HT-stimulated adenylyl cyclase, and alters REM sleep in rodent models. Supplied as a solid or as a DMSO solution for in vitro and in vivo research.
- Selective 5-HT7 receptor antagonist with high binding affinity.
- Demonstrated functional antagonism in adenylyl cyclase assays.
- Modulates REM sleep parameters in rodent studies.
- High purity suitable for research applications.
- Available as solid and ready-to-use DMSO solution.
- Store sealed and protect from moisture; follow supplier storage guidelines.
Medchemexpress LLC TLR7 agonist 3 | 1229024-78-5 | 99.9% | 312.41 g/mol | C18H24N4O | 100 MG
TLR7 agonist 3 is a small-molecule agonist of Toll-like receptor 7 used as a research reagent to stimulate innate immune responses and evaluate anticancer immunomodulatory strategies. It is supplied as a high-purity solid suitable for in vitro and in vivo studies.
- Potent agonist of Toll-like receptor 7 (TLR7) for immune activation studies.
- Applicable for conjugation to targeting ligands to direct activity to specific cell types.
- High purity solid suitable for analytical and biological assays.
- Soluble in DMSO (100 mg/mL) and ethanol (≥50 mg/mL); compatible with common in vivo formulations at ≥2.5 mg/mL.
- Offered in multiple pack sizes including 100 mg for dosing flexibility.
Medchemexpress LLC Ethyl 2-amino-4-methyl-5-((3-nitrophenyl)carbamoyl)-thiophene-3-carboxylate | 303141-21-1 | 99.7% | 10 MG
DC-S239 is a selective inhibitor of histone methyltransferase SET7 with reported in vitro activity (IC50 = 4.59 μM); supplied as a high-purity solid for research use.
- Selective SET7 inhibitor with IC50 = 4.59 μM.
- Reported antiproliferative activity in MCF7 and HL60 cells.
- High purity suitable for biochemical and cellular studies.
- Soluble in DMSO (125 mg/mL) for in vitro experiments.
- Stable as a powder at -20°C for long-term storage.
Medchemexpress LLC HY-52101 25mg , CMK CAS:821794-90-5 Purity:98%
Medchemexpress, HY-52101 25mg CMK CAS:821794-90-5 Formula:C18H19ClN4O2 Purity:98% CMK is a RSK2 kinase inhibitor, used for cancer treatment. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1594092-37-1 | Medchem Express | AZ191 | 5mg | 446260910 | HY-12277 | MFCD28015098 | 429.528 | C24H27N7O
Ambeed | 12H-Benzo[45]thieno[23-a]carbazole | 250mg | 682928390 | A1150534 | 222-21-9 | MFCD30291519 | 273.350 | C18H11NS
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Medchemexpress LLC HY-B0580A 5mg Medchemexpress, (S)-Ketorolac CAS:66635-92-5 Purity:>98%
Medchemexpress, HY-B0580A 5mg (S)-Ketorolac CAS:66635-92-5 (S)-Ketorolac is a nonsteroidal anti-inflammatory agent. (S)-ketorolac exhibits potent COX1 and COX2 enzyme inhibition [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1704740-52-2 | Medchem Express | AZ PFKFB3 26 | 5mg | 482203815 | HY-101971 | MFCD30742931 | 402.498 | C24H26N4O2
Medchem Express | EtDO-P4 | 5mg | 789373914 | HY-50055 | 245329-78-6 | MFCD11616162 | 516.767 | C31H52N2O4
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Medchemexpress LLC N-Boc-biocytin | 62062-43-5 | MFCD00133628 | >97.0% | 472.60 g/mol | C21H36N4O6S | 50 MG
N-Boc-Biocytin is a Boc-protected biotin PEG linker bearing a terminal carboxylic acid; it enables conjugation to primary amines through stable amide bond formation. The Boc group protects the amine during synthesis and can be cleaved under acidic conditions to reveal a free amine for subsequent derivatization. This reagent is intended for research use in peptide synthesis and bioconjugation workflows where a protected biotin handle is required.
- Boc-protected amine for controlled deprotection
- Terminal carboxylic acid for stable amide bond formation with primary amines
- Biotin functionality for affinity tagging and detection
- PEG spacer improves solubility and reduces steric hindrance
- Suitable for peptide synthesis and bioconjugation applications
eMolecules 941714-57-4 | Methyl 3-Bromopyrrole-2-carboxylate | Accela ChemBio (ASD) | MFCD23106341 | 204.023 | C6H6BrNO2 | 95.000 | COC(=O)c1[nH]ccc1Br | 10g | 697506666
Methyl 3-Bromopyrrole-2-carboxylate | Accela ChemBio (ASD) | 941714-57-4 | MFCD23106341 | 204.023 | C6H6BrNO2 | 95.000 | COC(=O)c1[nH]ccc1Br | 10g | 697506666
Medchemexpress LLC AZ PFKFB3 26 | 1704740-52-2 | MFCD30742931 | 99.2% | 402.49 g·mol-1 | C24H26N4O2 | 50 MG
AZ PFKFB3 26 is a research-grade small-molecule inhibitor of PFKFB3 (CAS 1704740-52-2) supplied as a powder for in vitro and preclinical studies. The compound has formula C24H26N4O2 and a molecular weight of 402.49 g·mol-1. Analytical data and handling information are provided to support experimental use.
- Documented purity available (COA shows ~99.2%).
- Suitable for in vitro studies; soluble in DMSO at ~5 mg/mL.
- Analytical data provided: COA, H NMR, LCMS, and SDS.
- Storage conditions specified for powder and solutions to preserve stability.
- Available in multiple research sizes, including 50 mg.
Medchemexpress LLC HY-102028 2mg Medchemexpress, KY1220 CAS:292168-79-7 Purity:>98%
Medchemexpress, HY-102028 2mg KY1220 CAS:292168-79-7 KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the Wnt/β-catenin pathway; with an IC50 of 2.1 μM in HEK293 reporter cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-12856 100mg , GSK503 CAS:1346572-63-1 Purity:98%
Medchemexpress, HY-12856 100mg GSK503 CAS:1346572-63-1 Formula:C31H38N6O2 Ki: 3 to 27 nM (EZH2) Purity:98% GSK503 is a potent and specific inhibitor of EZH2 methyltransferase with K i app values of 3 to 27 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 136668-42-3 | Medchem Express | Quiflapon | 5mg | 446255276 | HY-10037 | MFCD00900782 | 587.18 | C34H35ClN2O3S
Ambeed | 2-Phenylfuran | 100mg | 600830575 | A140685 | 17113-33-6 | MFCD00234628 | 144.173 | C10H8O
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![Medchemexpress LLC Urea, N-[4-(1-amino-5-isoquinolinyl)phenyl]-N'-[5-(1,1-dimethylethyl)-3-isoxazolyl]- | 1481641-08-0 | 98.9% | 401.46 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385494-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Urea, N-[4-(1-amino-5-isoquinolinyl)phenyl]-N'-[5-(1,1-dimethylethyl)-3-isoxazolyl]- | 1481641-08-0 | 98.9% | 401.46 | 50 MG
RIPK1-IN-4 is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase. It binds to a DLG-out inactive form of RIP1 with IC50s of 16 nM for RIP1 and 10 nM for ADP-Glo kinase.
- Potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase.
- Binds to a DLG-out inactive form of RIP1.
- For research use only.