Pyrroles
Medchemexpress LLC TLR7 agonist 3 | 1229024-78-5 | 99.9% | 312.41 g/mol | C18H24N4O | 100 MG
TLR7 agonist 3 is a small-molecule agonist of Toll-like receptor 7 used as a research reagent to stimulate innate immune responses and evaluate anticancer immunomodulatory strategies. It is supplied as a high-purity solid suitable for in vitro and in vivo studies.
- Potent agonist of Toll-like receptor 7 (TLR7) for immune activation studies.
- Applicable for conjugation to targeting ligands to direct activity to specific cell types.
- High purity solid suitable for analytical and biological assays.
- Soluble in DMSO (100 mg/mL) and ethanol (≥50 mg/mL); compatible with common in vivo formulations at ≥2.5 mg/mL.
- Offered in multiple pack sizes including 100 mg for dosing flexibility.
Medchemexpress LLC Ethyl 2-amino-4-methyl-5-((3-nitrophenyl)carbamoyl)-thiophene-3-carboxylate | 303141-21-1 | 99.7% | 10 MG
DC-S239 is a selective inhibitor of histone methyltransferase SET7 with reported in vitro activity (IC50 = 4.59 μM); supplied as a high-purity solid for research use.
- Selective SET7 inhibitor with IC50 = 4.59 μM.
- Reported antiproliferative activity in MCF7 and HL60 cells.
- High purity suitable for biochemical and cellular studies.
- Soluble in DMSO (125 mg/mL) for in vitro experiments.
- Stable as a powder at -20°C for long-term storage.
![Medchemexpress LLC Ethyl 2-amino-4-methyl-5-[(3-nitrophenyl)formamido]thiophene-3-carboxylate | 303141-21-1 | 99.7% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000233735.png-250.jpg)
Medchemexpress LLC Ethyl 2-amino-4-methyl-5-[(3-nitrophenyl)formamido]thiophene-3-carboxylate | 303141-21-1 | 99.7% | 50 MG
DC-S239 is a selective small-molecule inhibitor of the histone methyltransferase SET7 (SETD7) used for research applications. It is reported to inhibit SET7 with an IC50 of 4.59 μM and is supplied as a solid for laboratory use.
- Selective SET7 inhibitor with reported IC50 of 4.59 μM.
- High purity (99.7%).
- Molecular weight 349.36 g/mol; formula C15H15N3O5S.
- Solid, yellow-orange physical form suitable for handling and storage.
- Available as a 50 mg research vial.
Medchemexpress LLC HY-112180 10mg Medchemexpress, JNJ-678 CAS:1383450-81-4 Purity:>98%
Medchemexpress, HY-112180 10mg JNJ-678 CAS:1383450-81-4 JNJ-678 (JNJ-53718678) is a novel fusion protein inhibitor in clinical trials for the treatment of respiratory syncytial virus (RSV). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC UNC2025 hydrochloride | 2070015-17-5 | 100.0% | 513.12 | C28H41ClN6O | 25MG
UNC2025 hydrochloride is the hydrochloride salt of UNC2025, a potent, ATP-competitive, orally active dual Mer (MERTK) and FLT3 kinase inhibitor used in preclinical oncology research. It exhibits sub-nanomolar potency and favorable pharmacokinetic properties, and is supplied as a light yellow solid for laboratory use.
- Potent Mer and FLT3 inhibition (IC50 0.74 nM and 0.8 nM).
- High reported purity (99.96%).
- Solid form with light yellow to yellow appearance.
- Demonstrated >45-fold selectivity for MERTK versus Axl.
- Available in multiple pack sizes and solution aliquots for flexible dosing.
- Useful as a tool compound in preclinical oncology models, including acute leukemia research.
Medchemexpress LLC HY-15573 5mg Medchemexpress, EI1 CAS:1418308-27-6 Purity:>98%
Medchemexpress, HY-15573 5mg EI1 CAS:1418308-27-6 EI1 (KB-145943) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-12747 5mg Medchemexpress, DC_517 CAS:500017-70-9 Purity:>98%
Medchemexpress, HY-12747 5mg DC_517 CAS:500017-70-9 DC_517 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC50 and a Kd of 1.7 μM and 0.91 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.