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Filtered Search Results
Medchemexpress LLC Z-YVAD-AFC | 201608-13-1 | 98.9% | 811.76 | 10 MG
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Z-YVAD-AFC is a fluorescent substrate specifically designed for Caspase-1, which allows for the detection and measurement of Caspase-1 activity. It is intended for research use only and not for patient use.
- Fluorescent substrate for Caspase-1
- Can be used to detect Caspase-1 activity
- Can be used to measure Caspase-1 activity
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Medchemexpress LLC 1,2,4-trideoxy-4-(methylamino)-1-(4-pentylphenyl)-D-erythro-pent-1-enitol hydrochloride | 1072443-89-0 | >=98.0% | 313.86 g/mol | C17H27NO2.HCl | 10 MG
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SK1-I is a sphingosine analog and a selective, competitive inhibitor of sphingosine kinase 1 (SPHK1) with a reported Ki of approximately 10 μM. It is supplied for research use and is used in biochemical and cell-based studies to modulate sphingolipid signaling, enhance autophagy, and evaluate antitumor activity.
- Selective SPHK1 inhibitor (Ki ≈ 10 μM).
- Sphingosine analog used in biochemical and cellular assays.
- Reported to enhance autophagy and show antitumor effects in preclinical studies.
- Supplied in small milligram quantities for research use only.
- Common applications include pathway modulation, proliferation, and apoptosis studies.
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Medchemexpress LLC 3′-Azido-2′,3′-dideoxyuridine | 84472-85-5 | 99.1% | 253.21 g·mol⁻¹ | C9H11N5O4 | 25 MG
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3′-Azido-2′,3′-dideoxyuridine (AzdU, CAS 84472-85-5) is an azido-modified uridine nucleoside analog used in antiviral research and nucleotide chemistry. It acts as an inhibitor of HIV replication in cell-based assays and is provided as a solid for laboratory use.
- Inhibits HIV replication in vitro.
- High chemical purity (99.1%).
- Molecular formula C9H11N5O4; molecular weight 253.21 g·mol⁻¹.
- White to off-white solid suitable for synthesis and biochemical assays.
- Powder stable at -20°C for long-term storage; solutions recommended at -80°C for extended storage.
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Medchemexpress LLC Doxorubicin-SMCC 100mg | 400647-59-8 | 100 MG
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Doxorubicin-SMCC is a doxorubicin-based antibody-drug conjugate linker-drug conjugate designed for ADC research, pairing a DNA topoisomerase II inhibitor payload with a non-cleavable SMCC linker for stable conjugation and in vitro studies.
- Contains an SMCC non-cleavable linker for stable thiol coupling.
- Delivers doxorubicin, a DNA topoisomerase II inhibitor, as the cytotoxic payload.
- Purity: 98.8%.
- Formula: C39H42N2O14; molecular weight: 762.76.
- Soluble in DMSO at 125 mg/mL (ultrasonic recommended).
- Available in a 100 MG pack size.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000371295 5-FAM MALEIMIDE 100MG
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ABOSYN 3-(4-(4-(2-hydroxyethyl)piperidin-1-yl)phenyl)piperidine-2,6-dione, 2736510-46-4
3-(4-(4-(2-hydroxyethyl)piperidin-1-yl)phenyl)piperidine-2,6-dione, 2736510-46-4
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eMolecules N-BOC-2-2-AMINOETHOXYETHY 1G
5000224554 N-BOC-2-2-AMINOETHOXYETHY 1G
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Medchemexpress LLC Maleimide-PEG-COOH | 96.8% | 2000 | 500 MG
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Maleimide-PEG-COOH (MW 2000) is a PEG derivative consisting of Maleimide, PEG units, and a carboxyl (-COOH) group. The carboxyl group readily forms a stable amide bond with amino groups or an ester bond with hydroxyl groups. The Maleimide component forms a stable thioether bond with sulfhydryl (-SH) groups.
- Carboxyl group forms a stable amide bond with amino groups or an ester bond with hydroxyl groups.
- Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups.
- For research use only.
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Medchemexpress LLC HY-100110 5mg Medchemexpress, KNK437 CAS:218924-25-5 Purity:>98%
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Medchemexpress, HY-100110 5mg KNK437 CAS:218924-25-5 KNK437 is a HSP inhibitor, and inhibits the induction of HSP105, HSP70, and HSP40. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Z -Viaminate 50mg | 50MG
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Z -Viaminate 50mg | 50MG
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Medchemexpress LLC Z -Viaminate 10mg | 10MG
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Z -Viaminate 10mg | 10MG
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Medchemexpress LLC E/Z-Locostatin | 133812-16-5 | 99.52% | 245.27 | 50 MG
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E/Z-Locostatin is a racemic mixture of Locostatin. This potent RKIP inhibitor binds to Raf kinase inhibitor RKIP protein, disrupting its interaction with Raf-1 kinase and G protein-coupled receptor kinase 2. It inhibits cell proliferation and migration.
- Potent RKIP inhibitor
- Disrupts interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2
- Inhibits cell proliferation
- Inhibits cell migration
- Aggravates thioacetamide-induced acute liver failure in mice
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Medchemexpress LLC Boc-11-aminoundecanoic acid | 10436-25-6 | 98.0% | 301.42 | 5 G
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Boc-11-aminoundecanoic acid is an alkyl/ether-based PROTAC linker that can be utilized in the synthesis of MS432 (HY-130602). It is intended for research use only.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of MS432 (HY-130602)
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Medchemexpress LLC Protac Mcl1 degrader-1 | 2163793-38-0 | 98.1% | 909.84 g/mol | C45H45BrN6O8S | 5MG
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PROTAC Mcl1 degrader-1 is a cereblon-based proteolysis targeting chimera (PROTAC) that induces ubiquitination and proteasomal degradation of the anti-apoptotic protein Mcl-1. It is provided as a small-molecule research compound for in vitro and in vivo studies; reported properties include molecular formula C45H45BrN6O8S, molecular weight 909.84 g/mol, CAS 2163793-38-0, and a reported IC50 of 0.78 μM for Mcl-1 activity. Recommended solvents and in vivo formulations are provided in the manufacturer datasheet.
- Induces cereblon-mediated degradation of Mcl-1.
- Potent Mcl-1 activity with reported IC50 of 0.78 μM.
- Molecular weight 909.84 g/mol and formula C45H45BrN6O8S.
- High solubility in DMSO; documented in vitro and in vivo formulations.
- Intended for biochemical and cell-based research applications.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377931 7-HYDROXYMETHYL-10 1 1MG
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