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Filtered Search Results
Medchemexpress LLC (E/Z)-Icerguastat | 13098-73-2 | 99.4% | 196.64 | 5 MG
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(E/Z)-Icerguastat is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). It is designed for protein misfolding diseases research.
- Selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A)
- Can be used for protein misfolding diseases research
- Target is Phosphatase
- Pathway is Metabolic Enzyme/Protease
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5000385211 E Z -ICERGUASTAT 100MG
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Medchemexpress LLC (Rac)-NSC305787 | 785718-37-8 | 99.3% | 445.42 | 1 ML
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NSC305787 is an inhibitor of ezrin with a Kd of 5.85 μM. It inhibits the phosphorylation of ezrin caused by PKCΙ with an IC50 of 8.3 μM, and exhibits antitumor activity. NSC305787 inhibits PKCΙ phosphorylation of Ezrin, Moesin, Radixin, and MBP, with IC50s of 8.3, 9.4, 55, and 58.9 μM, respectively. It binds to PKCΙ with a Kd value of 172.4 μM, and inhibits ezrin T567 phosphorylation primarily by binding to ezrin, rather than through inhibition of PKCΙ kinase activity.
- Shows inhibitory activity against ezrin-mediated invasion of K7M2 osteosarcoma cells.
- Reduces cell motility phenotypes in zebrafish and blocks osteosarcoma metastatic growth in lung organ culture.
- Suppresses ezrin-dependent osteosarcoma metastatic growth in mouse lung.
- Inhibits pulmonary metastasis in a transgenic mouse model of osteosarcoma.
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eMolecules Medchem Express / RI-1 / 5mg / 446265442 / HY-15317 / / 415713-60-9 / MFCD00814248 / 361.600 / C14H11Cl3N2O3
Medchem Express / RI-1 / 5mg / 446265442 / HY-15317 / / 415713-60-9 / MFCD00814248 / 361.600 / C14H11Cl3N2O3
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eMolecules Medchem Express / Aldoxorubicin / 5mg / 446267301 / HY-16261 / / 1361644-26-9 / MFCD15146982 / 750.758 / C37H42N4O13
Medchem Express / Aldoxorubicin / 5mg / 446267301 / HY-16261 / / 1361644-26-9 / MFCD15146982 / 750.758 / C37H42N4O13
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Medchemexpress LLC Dapagliflozin ((2S)-1,2-propanediol, hydrate) | 960404-48-2 | 100.0% | 502.98 | C24H35ClO9 | 100 MG
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Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the propanediol monohydrate form of a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor supplied as a solid for research and analytical use in diabetes and metabolic studies. The material is analytically characterized and provided in laboratory-scale pack sizes for experimental workflows.
- Selective SGLT2 inhibitor for metabolic and diabetes research.
- High purity by HPLC (99.99%).
- Appearance: white to off-white solid.
- Supplied in convenient laboratory pack sizes including 100 MG.
- Analytical identity confirmed by 1H NMR and LCMS.
- Store sealed, away from moisture; in solvent store at -80°C (up to 2 years) or -20°C (up to 1 year).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC (2S,3R)-2,3,4-Trihydroxybutanal-13C-2 | 90913-09-0 | 99.4% | 121.10 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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(2S,3R)-2,3,4-Trihydroxybutanal-13C-2 is a 13C labeled compound primarily used in research. It incorporates stable heavy isotopes for quantitation in drug development processes.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of carbon for quantitation.
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Chem-Impex International, Inc. N-Hydroxysuccinimide | 6066-82-6 | MFCD00005516 | 1KG
N-Hydroxysuccinimide, 6066-82-6, MFCD00005516, 1KG
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Chem-Impex International, Inc. N-Hydroxysuccinimide | 6066-82-6 | MFCD00005516 | 100G
N-Hydroxysuccinimide, 6066-82-6, MFCD00005516, 100G
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Chem-Impex International, Inc. N-Hydroxysuccinimide | 6066-82-6 | MFCD00005516 | 25G
N-Hydroxysuccinimide, 6066-82-6, MFCD00005516, 25G
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eMolecules 3-N-BOC-N-METHYLAMINOPROP 1G
5000193331 3-N-BOC-N-METHYLAMINOPROP 1G
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eMolecules R-PYRROLIDIN-2-YL-ACET 250MG
5000193216 R-PYRROLIDIN-2-YL-ACET 250MG
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AARON CHEMICALS LLC
NC3909337 3-3 4IMETHOXYPHENYLPROPION
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Medchemexpress LLC (E/Z)-Locostatin | 133812-16-5 | 99.5% | 245.27 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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(E/Z)-Locostatin ((E/Z)-UIC-1005) is a racemic form of Locostatin. Locostatin (UIC-1005) is a potent RKIP inhibitor that binds to the Raf kinase inhibitor RKIP protein. It disrupts the interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2. (E/Z)-Locostatin inhibits cell proliferation and migration and has been shown to aggravate thioacetamide-induced acute liver failure in mice.
- Potent RKIP inhibitor
- Disrupts interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2
- Inhibits cell proliferation and migration
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Innovative Research Inc Ms PAI1 Rcmb Act Btn lbl 500ug
Mouse PAI-1 Recombinant Active Biotin Labeled 500 ug -
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