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Filtered Search Results
Medchemexpress LLC (Rac)-minzasolmin | 1802518-63-3 | 99.9% | 425.59 g/mol | C23H31N5OS | 10MG
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(Rac)-Minzasolmin is a racemic, brain-penetrant inhibitor of α-synuclein misfolding developed for research into synucleinopathies. It modulates early-stage aggregation, can revert membrane-bound oligomers to monomers, and has shown efficacy in α-synuclein transgenic models relevant to Parkinson's disease and dementia with Lewy bodies.
- Brain-penetrant small molecule suitable for in vivo and in vitro studies.
- Inhibits α-synuclein misfolding and early-stage aggregation.
- Promotes reversion of membrane-bound oligomers to monomers.
- Demonstrated activity in α-synuclein transgenic models.
- High purity for research use (≈99.9%).
- Molecular formula C23H31N5OS; molecular weight 425.59 g/mol.
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Apexbio Technology LLC GW311616 hydrochloride 197890-44-1 5mg
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GW311616 hydrochloride (CAS 197890-44-1) is a selective cell-permeable inhibitor of human neutrophil elastase (HNE) exhibiting an IC50 of 22 nM and a Ki of 0 13 nM in enzymatic assays It demonstrates pronounced selectivity with IC50 values exceeding 100 M for trypsin cathepsin G and plasmin and greater than 3 M for chymotrypsin and tissue plasminogen activator In human whole blood assays GW311616 hydrochloride achieves an IC50 of 0 67 M The compound is orally bioavailable and displays prolonged activity in dog blood samples indicating a sustained inhibitory effect on neutrophil elastase GW311616 hydrochloride is valuable for investigating HNE s role in inflammation and related pathologies
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Medchemexpress LLC N-(hydroxymethyl)acetamide | 625-51-4 | MFCD00014417 | 96.5% | 89.09 g/mol | C3H7NO2 | 5 G
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N-(Hydroxymethyl)acetamide is a low-molecular-weight biochemical reagent used as a model molecule in studies of hydrogen bonding and molecular interactions. It is supplied as a characterized solid with available analytical documentation for laboratory and materials research applications.
- Small, well-characterized molecule suitable for hydrogen-bonding studies.
- Molecular formula C3H7NO2; molecular weight 89.09 g/mol.
- Purity 96.46% as reported on the certificate of analysis.
- Available in multiple pack sizes, including 5 g, for flexible lab use.
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Medchemexpress LLC Tert-butyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl carbamate | 106984-09-2 | MFCD07779195 | 99.5% | 293.36 g/mol | C13H27NO6 | 500 MG
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Boc-NH-PEG4 is a Boc-protected PEG4 linker used as a hydrophilic spacer in proteolysis-targeting chimera (PROTAC) synthesis and other bioconjugation chemistries. It combines a protected amine and a terminal hydroxyl to allow stepwise functionalization, improve aqueous solubility, and provide conformational flexibility during linker assembly.
- Provides a Boc-protected amine for orthogonal deprotection and coupling.
- Terminating hydroxyl enables diverse functionalization reactions.
- PEG4 spacer increases solubility and molecular flexibility.
- High purity supports reliable synthetic workflows (listed ~99.5%).
- Molecular weight ~293.36 g/mol; formula C13H27NO6.
- Supplied in laboratory-scale quantities for research use.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000370781 5-FAM MALEIMIDE 25MG
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Medchemexpress LLC (Rac)-BAY1238097 | 1564268-19-4 | 99.7% | 451.56 | 10 MM 1 ML
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(Rac)-BAY1238097 is a BET inhibitor, with an IC50 of 1.02 μM for BRD4. It is used in cancer research.
- BET inhibitor
- IC50 of 1.02 μM for BRD4
- Used in cancer research
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Medchemexpress LLC 2R 3S-E1R 50mg | 1424832-60-9 | 232.28 g/mol | C13H16N2O2 | 50 MG
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(2R,3S)-E1R is the (2R,3S) enantiomer of E1R and functions as a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for preclinical research into cognition and memory disorders. Supplied as a powder for laboratory use (CAS 1424832-60-9; C13H16N2O2; MW 232.28 g/mol). For research use only.
- Solid powder, light yellow.
- CAS number 1424832-60-9.
- Molecular formula C13H16N2O2; molecular weight 232.28 g/mol.
- Storage: powder -20°C (3 years), 4°C (2 years); in solvent -80°C (6 months), -20°C (1 month).
- Reported purity ~98.8% (supplier specification).
- Intended for preclinical research; not for human or clinical use.
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Cayman Chemical NArachidonyl Maleimide
A potent inhibitor of monoacylglycerol lipase (IC50 = 140 nM in rat cerebellar membranes)
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Medchemexpress LLC (3S,5S)-pitavastatin calcium | 254452-92-1 | MFCD28138313 | 99.9% | 440.49 g·mol^-1 | C25H24FNO4 · 1/2 Ca | 5 MG
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(3S,5S)-Pitavastatin calcium is the 3-epimer of pitavastatin calcium, a potent HMG-CoA reductase inhibitor used for cardiovascular disease research. It is supplied as the calcium salt and is intended for research use, with high reported purity suitable for analytical and biological studies.
- High purity (99.9%) suitable for analytical and biological assays.
- Molecular formula C25H24FNO4 · 1/2 Ca.
- Molecular weight 440.49 g·mol^-1.
- Available in small milligram quantities for laboratory use.
- Useful as a reference standard or for impurity profiling.
- Provided as a solid, white to off-white powder.
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Medchemexpress LLC C12-113 | 1220890-27-6 | 98.6% | 854.47 | 5 MG
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C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. It can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice.
- Lipidoid delivery agent
- Can transfect siRNA into cells
- Can be combined with other lipids to form LNPs for mRNA delivery
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eMolecules (S)-2-(CBZ-AMINO)-3-(1-BOC-PIPERIDIN-4-YL)PROPANOIC ACID | 1820583-71-8 | MFCD27991361 | 1g
AstaTech | (S)-2-(CBZ-AMINO)-3-(1-BOC-PIPERIDIN-4-YL)PROPANOIC ACID | 1g | 233629008 | 56540 | 95.000 | 1820583-71-8 | MFCD27991361 | 406.479 | C21H30N2O6
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Medchemexpress LLC (Rac)-ZLc-002 | 99.0% | 231.25 | 50 MG
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(Rac)-ZLc-002 is an inhibitor of nNOS interaction with nitric oxide synthase 1 adaptor protein (NOS1AP). It suppresses inflammatory nociception and chemotherapy-induced neuropathic pain. Additionally, it synergizes with Paclitaxel to reduce tumor cell viability.
- Reduces co-immunoprecipitation of NOS1AP with nNOS immunoprecipitated from primary cultured cortical neurons
- Synergizes to reduce tumor cell viability
- Attenuates mechanical and cold allodynia evoked by Paclitaxel
- Reduces formalin-evoked nociceptive behavior and Fos-like immunoreactivity in the spinal dorsal horn
- Attenuates chronic mild stress (CMS)‐induced anxiogenic behavior
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![eMolecules 2-Bromo-7-(tert-butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-3-carboxylic acid | 1823840-73-8 | MFCD27939610 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502168013.JPG-250.jpg)
eMolecules 2-Bromo-7-(tert-butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-3-carboxylic acid | 1823840-73-8 | MFCD27939610 | 1g
Synthonix - Stock | 2-Bromo-7-(tert-butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-3-carboxylic acid | 1g | 495875002 | B69701 | | 1823840-73-8 | MFCD27939610 | 346.181 | C12H16BrN3O4
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Medchemexpress LLC (2S,3S)-2-(Benzyl(methyl)amino)-3-methylpentanoic acid | 4125-97-7 | 99.2% | C14H21NO2 | 1 G
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(2S,3S)-2-(Benzyl(methyl)amino)-3-methylpentanoic acid is an isoleucine derivative. Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances.
- Is an isoleucine derivative
- Used as ergogenic supplements
- Influences the secretion of anabolic hormones
- Supplies fuel during exercise
- Aids mental performance during stress-related tasks
- Helps prevent exercise-induced muscle damage
- Beneficial as an ergogenic dietary substance
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Medchemexpress LLC (2S)-OMPT (triethylamine) | 1217471-69-6 | 98.0% | 1 MG
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A 98% solution of (2S)-OMPT (triethylamine) in ethanol:chloroform (1:1) used as a chiral ligand for asymmetric catalysis and enantioselective synthesis.
- Chiral ligand for asymmetric catalysis and enantioselective synthesis.
- 98.0% purity.
- Supplied as a solution in ethanol:chloroform (1:1) for immediate use.
- Molecular weight 668.99 g/mol; formula C34H73N2O6PS.
- Store at -20°C; solution stable for up to 2 years.
- Available in a 1 mg vial for small-scale research applications.
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