Pyrrolidines
Medchemexpress LLC 20-hc-me-pyrrolidine | 00-00-0 | 99.7% | C28H47NO2 | 10MG
20-HC-Me-Pyrrolidine is a small-molecule research reagent that inhibits Aster proteins (Aster-A, Aster-B, Aster-C). It is provided as a solid with high reported purity and characterized potency for in vitro biochemical studies; solvent and storage guidelines support reliable handling in research workflows.
- Potent inhibitor of Aster proteins: IC50 0.11 μM (Aster-A), 0.06 μM (Aster-B), 0.71 μM (Aster-C).
- High purity (99.69%) suitable for biochemical assays.
- Soluble in DMSO at 6.67 mg/mL (15.52 mM) for stock solutions.
- Stable when protected from light and stored under inert atmosphere per handling instructions.
- Available in small-scale quantities to support discovery and assay development.
Medchemexpress LLC Boc-N-PEG2-MS | 302331-20-0 | 98.0% | C10H21NO6S | 25 MG
Boc-N-PEG2-MS is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These PROTAC molecules function by bringing together an E3 ubiquitin ligase and a target protein through two connected ligands, ultimately leading to the selective degradation of the target protein via the intracellular ubiquitin-proteasome system.
- PEG-based linker
- Essential for PROTAC synthesis
- Enables targeted protein degradation
- Utilizes the ubiquitin-proteasome system
Medchemexpress LLC Boc-N-PEG2-MS | 302331-20-0 | 98.0% | C10H21NO6S | 100 MG
Boc-N-PEG2-MS is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Synthesis of PROTACs
Medchemexpress LLC (1S,2S,3R)-DT-061 | 1809427-20-0 | 99.8% | 520.52 | 50 MG
(1S,2S,3R)-DT-061 is an enantiomer of DT-061. It is an orally active activator of protein phosphatase 2A (PP2A). (1S,2S,3R)-DT-061 can be used as a negative control in the research of KRAS-mutant and MYC-driven lung cancer tumorigenesis.
- Enantiomer of DT-061
- Orally active activator of protein phosphatase 2A (PP2A)
- Can be used as a negative control
- Relevant for research in KRAS-mutant and MYC-driven lung cancer tumorigenesis
Medchemexpress LLC (1S,2S,3R)-DT-061 | 1809427-20-0 | 99.8% | 520.52 | 25 MG
(1S,2S,3R)-DT-061 is an enantiomer of DT-061 and an orally active activator of protein phosphatase 2A (PP2A). It can be utilized as a negative control in research pertaining to KRAS-mutant and MYC-driven lung cancer tumorigenesis.
- Orally active activator of protein phosphatase 2A (PP2A).
- Can be utilized as a negative control in research.
- Potential application in therapy of KRAS-mutant and MYC-driven tumorigenesis.
Medchemexpress LLC (1S,2S,3R)-DT-061 | 1809427-20-0 | 99.8% | 520.52 | 1 ML
(1S,2S,3R)-DT-061 is an enantiomer of DT-061, an orally active activator of protein phosphatase 2A (PP2A). This product can be used as a negative control in the research of KRAS-mutant and MYC-driven lung cancer tumorigenesis.
- Enantiomer of DT-061
- Orally active activator of protein phosphatase 2A (PP2A)
- Used as a negative control in KRAS-mutant and MYC-driven lung cancer tumorigenesis research
Medchemexpress LLC (1S,2S,3R)-DT-061 | 1809427-20-0 | 99.77% | 520.52 | 100 MG
(1S,2S,3R)-DT-061 is an enantiomer of DT-061 (HY-112929). DT-061 is an orally active activator of protein phosphatase 2A (PP2A). (1S,2S,3R)-DT-061 can be used as a negative control in the research of KRAS-mutant and MYC-driven lung cancer tumorigenesis.
- Enantiomer of DT-061
- Used as a negative control in KRAS-mutant and MYC-driven lung cancer tumorigenesis research
eMolecules (R)-1-N-BOC-2-CYANO-PYRROLIDINE | 228244-20-0 | MFCD06411382 | 25g
AstaTech | (R)-1-N-BOC-2-CYANO-PYRROLIDINE | 25g | 213341365 | B66765 | 95.000 | 228244-20-0 | MFCD06411382 | 196.250 | C10H16N2O2
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Medchemexpress LLC 20-Hc-me-pyrrolidine | 00-00-0 | 99.7% | 429.68 g/mol | C28H47NO2 | 5 MG
20-HC-Me-Pyrrolidine is a small-molecule inhibitor of Aster proteins that blocks Aster-mediated cholesterol binding and transfer and inhibits LDL-derived cholesterol movement to the endoplasmic reticulum. Supplied as a high-purity research chemical for biochemical and cellular studies.
- Potent inhibitor of Aster proteins with reported IC50s Aster-A 0.11 μM, Aster-B 0.06 μM, Aster-C 0.71 μM.
- High purity suitable for research applications (reported ~99.69%).
- Well-characterized solubility in DMSO (≈6.67 mg/mL) for stock preparations.
- Recommended storage at 4°C; stock solutions stable at -80°C (6 months) or -20°C (1 month).
- Molecular formula C28H47NO2; molecular weight 429.68 g/mol.
eMolecules 1-(2,5-DIOXO-1-PYRROLIDINYL) 5-METHYL (S)-2-(BOC-AMINO)PENTANEDIOATE | 39538-20-0 | | 1g
AstaTech | 1-(2,5-DIOXO-1-PYRROLIDINYL) 5-METHYL (S)-2-(BOC-AMINO)PENTANEDIOATE | 1g | 601098475 | AC8547 | 95.000 | 39538-20-0 | | 358.347 | C15H22N2O8
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Sigma Aldrich Ethyl (R E)-2-((Mesitylsulfinyl)Imino)Acetate
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Ethyl (S E)-2-((Mesitylsulfinyl)Imino)Acetate
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 3,4-Dichlorophenylacetylene
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC Crocin II | 55750-84-0 | MFCD11111454 | 98.0% | 10 MG
Crocin II is a natural glycoside isolated from Gardenia jasminoides, supplied as a solid research reagent and analytical standard with reported antioxidant, anticancer, and antidepressant activities. The product is characterized by a molecular weight of 814.82 g/mol, CAS number 55750-84-0, and a recorded purity around 98%. Recommended storage is -20°C and protect from light; solubility in DMSO is approximately 25 mg/mL.
- Natural glycoside isolated from Gardenia jasminoides
- High purity suitable for analytical applications
- Molecular weight 814.82 g/mol and CAS 55750-84-0
- Soluble in DMSO (≈25 mg/mL) for in vitro use
- Storage recommended at -20°C and protect from light
Medchemexpress LLC Tert-butoxycarbonyl-L-valyl-L-valine | 69209-73-0 | 97.0% | 316.39 g/mol | C15H28N2O5 | 10 G
(tert-Butoxycarbonyl)-L-valyl-L-valine is a Boc-protected dipeptide derived from two valine residues, used as a building block in peptide synthesis and related biochemical research applications.
- Boc-protected L-valyl-L-valine dipeptide for peptide synthesis.
- White to off-white powder; molecular weight 316.39 g/mol.
- Chemical formula C15H28N2O5; CAS number 69209-73-0.
- Purity 97.0%.
- Typical package: 10 G; powder storage -20°C (3 years), 4°C (2 years).
- In solvent storage -80°C (6 months), -20°C (1 month).
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