Quinolines and derivatives
Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.
Quantity
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- (221)
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- (40)
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- (12)
- (48)
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- (37)
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- (1)
- (1)
- (8)
- (135)
- (1)
- (9)
- (16)
- (1)
- (36)
- (1)
- (1)
- (1)
- (1)
- (1)
- (189)
- (1)
- (1)
- (17)
- (1)
- (17)
- (17)
- (6)
- (1)
Molecular Weight (g/mol)
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- (1)
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- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (7)
- (21)
- (26)
- (2)
- (30)
- (4)
- (6)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
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- (5)
- (2)
- (6)
- (5)
- (2)
- (1)
- (11)
- (1)
- (2)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (25)
- (16)
- (2)
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- (1)
- (1)
- (1)
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- (2)
- (1)
- (1)
- (1)
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- (1)
- (1)
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- (1)
- (1)
- (4)
- (4)
- (8)
- (2)
- (1)
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- (1)
- (1)
- (6)
- (2)
- (1)
- (1)
- (2)
- (1)
- (6)
- (1)
- (20)
- (1)
- (5)
- (1)
- (3)
- (5)
- (1)
- (2)
- (2)
- (2)
- (2)
- (8)
- (1)
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- (7)
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- (4)
- (1)
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- (2)
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- (1)
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- (1)
- (4)
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- (2)
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- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (13)
- (1)
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- (2)
- (4)
- (3)
- (4)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (19)
- (2)
- (1)
- (2)
- (4)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (4)
- (5)
- (1)
- (2)
- (1)
- (1)
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- (4)
- (3)
- (2)
- (1)
- (9)
- (5)
- (2)
- (3)
- (3)
- (2)
- (5)
- (6)
- (3)
- (13)
- (2)
- (1)
- (1)
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- (1)
- (1)
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- (1)
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- (2)
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- (1)
- (1)
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- (2)
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- (1)
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- (4)
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- (3)
- (7)
- (1)
- (1)
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- (3)
- (7)
- (5)
- (2)
- (1)
- (10)
- (1)
- (1)
Percent Purity
- (1)
- (2)
- (2)
- (4)
- (1)
- (2)
- (2)
- (4)
- (2)
- (2)
- (6)
- (2)
- (7)
- (4)
- (3)
- (2)
- (2)
- (5)
- (2)
- (1)
- (14)
- (1)
- (1)
- (23)
- (42)
- (24)
- (18)
- (83)
- (3)
- (17)
- (3)
- (5)
- (8)
- (1)
- (6)
- (1)
- (5)
- (1)
- (6)
- (5)
- (2)
- (5)
- (2)
- (6)
- (2)
- (2)
- (4)
- (1)
- (25)
- (19)
- (71)
- (1)
- (109)
- (3)
- (1)
- (2)
- (61)
- (5)
- (1)
- (1)
Physical Form
- (2)
- (299)
- (2)
- (2)
- (25)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (3)
- (9)
- (3)
- (2)
- (62)
- (2)
- (5)
- (29)
- (3)
Boiling Point
- (2)
- (1)
- (1)
- (1)
- (3)
- (3)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (4)
- (2)
- (1)
- (3)
- (1)
- (2)
- (2)
- (5)
- (3)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (12)
- (4)
- (1)
- (5)
- (3)
- (5)
- (2)
- (2)
- (3)
- (2)
- (1)
- (1)
- (3)
- (5)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
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1,681
Medchemexpress LLC Q AGAROSE 6FF 25ML
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Q AGAROSE 6FF 25ML
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Medchemexpress LLC 1 4-DICHLORO 5-CARBO 5 mg
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1 4-DICHLORO 5-CARBO 5MG
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1,683
Medchemexpress LLC (S,R,S)-AHPC-CO-C9-acid | 2172819-78-0 | 95.0% | 628.82 | 50 MG
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(S,R,S)-AHPC-CO-C9-acid is an E3 ligase ligand-linker conjugate that can be connected to the ligand for protein to form PROTACs. This compound is intended for research use only.
- Functions as an E3 ligase ligand-linker conjugate.
- Can be connected to ligand for protein to form PROTACs.
- Exhibits antiproliferative activity against human NCI-H69 cells.
- Has an IC50 > 40 μM against NCI-H69 cells.
- Appearance: solid, white to off-white.
- Ships at room temperature in continental US.
- Storage conditions: 4°C, protect from light, stored under nitrogen.
- Soluble in various solvents including DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil.
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1,684
Medchemexpress LLC Amdiglurax | 1270138-40-3 | 99.6% | 366.50 | 200 MG
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Amdiglurax | 1270138-40-3 | 99.6% | 366.50 | 200 MG
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1,685
Medchemexpress LLC VARI FLUOR 555 CARBO 1 mg
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VARI FLUOR 555 CARBO 1MG
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1,686
Medchemexpress LLC VARI FLUOR 488 CARBO 5 mg
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VARI FLUOR 488 CARBO 5MG
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1,687
Medchemexpress LLC ACRIDINE ORANGE 10-N 5 mg
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ACRIDINE ORANGE 10-N 5MG
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1,688
Medchemexpress LLC Danofloxacin mesylate | 119478-55-6 | 99.9% | 500 MG
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Danofloxacin mesylate is a fluoroquinolone veterinary drug with a broad spectrum of bactericidal activity. Its primary mechanism of action involves inhibiting bacterial DNA gyrase. Additionally, it acts as a substrate for ATP-dependent efflux transporters, specifically P-gp and MRP2.
- Fluoroquinolone veterinary drug
- Broad spectrum bactericidal activity
- Inhibits bacterial DNA gyrase
- Substrate for ATP-dependent efflux transporters (P-gp and MRP2)
- Intended for research use only
- Inhibits bovine bacterial respiratory pathogens (e.g., Pasteurella hemolyticus, Pasteurella multocida, and Haemophilus somnosus)
- Exhibits asymmetric transport across Caco-2 cells
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1,689
Medchemexpress LLC DCZ0415 | 2242470-43-3 | 99.8% | 200 MG
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DCZ0415 is a potent TRIP13 inhibitor that impairs nonhomologous end joining repair and inhibits NF-κB activity. It induces anti-myeloma activity in vitro, in vivo, and in primary cells derived from drug-resistant myeloma patients.
- Significantly decreases colony formation
- Inhibits cell proliferation
- Decreases viability in MM cells
- Induces apoptotic cell death
- Causes accumulation of MM cells in G0/G1 phase
- Decreases protein levels of phosphorylated iκBα and NF-κB
- Exerts cytotoxic effects by inhibiting DNA synthesis
- Reduces growth of MM cells-induced tumors in immune-deficient mice
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1,690
Medchemexpress LLC VK-II-86 | 955371-84-3 | 93.3% | 420.50 | 500 MG
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VK-II-86 is a Carvedilol analogue that lacks antagonist activity at β-adrenoceptors in hypokalaemia. This compound effectively prevents hypokalaemia-induced ventricular arrhythmia through its multi-channel effects, counteracting all hypokalaemia-induced changes in ion channel activity and oxidative stress. For research use only.
- Carvedilol analogue
- Lacks antagonist activity at β-adrenoceptors
- Prevents hypokalaemia-induced ventricular arrhythmia
- Exhibits multi-channel effects
- Counters hypokalaemia-induced changes in ion channel activity
- Counters hypokalaemia-induced oxidative stress
- Markedly reduces non-sustained and sustained ventricular tachyarrhythmias in a hypokalaemic murine whole-heart model
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1,691
Medchemexpress LLC Nintedanib esylate | 656247-18-6 | 649.76 | 50 MG
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Nintedanib esylate | 656247-18-6 | 649.76 | 50 MG
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1,692
Medchemexpress LLC Amino-PEG12-amine | 361543-12-6 | 99.9% | 588.73 | 1 G
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Amino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. This product is intended for research use only.
- Used in the synthesis of PROTACs
- Molecular weight of 588.73
- Purity of 99.92% by HPLC
- Colorless to off-white solid-liquid mixture
- Store at 4°C, protected from light
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1,693
Medchemexpress LLC Istradefylline | 155270-99-8 | MFCD00928421 | 99.89% | 384.43 | 200 MG
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Istradefylline is a potent, selective, and orally active antagonist of the adenosine A2A receptor, demonstrating a high affinity for this receptor in various experimental models, including those relevant to Parkinson's disease. It exhibits significantly greater affinity for the A2A receptor compared to the A1 receptor, making it a valuable tool for research into neurological conditions and adenosine signaling pathways.
- Highly potent and selective adenosine A2A receptor antagonist.
- Orally active in experimental models.
- Displays neuroprotective effects in Parkinson's disease models.
- Reverses drug-induced catalepsy and hypokinesia.
- Enhances antiparkinsonian activity when combined with dopamine agonists.
- Prevents astrogliosis in primary rat striatal astrocytes.
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1,694
Medchemexpress LLC DGAT1 Human Pre-desi 1set | 1SET
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DGAT1 Human Pre-desi 1set | 1SET
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1,695
Medchemexpress LLC RU-521 | 2262452-06-0 | 100.0% | 415.23 | 50 MG
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RU.521 is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor. It inhibits cGAS-mediated interferon upregulation and suppresses dsDNA-activated reporter activity.
- Inhibits cGAS-mediated interferon upregulation.
- Suppresses dsDNA-activated reporter activity with an IC50 of 0.7 μM.
- Reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS).
- Reduces symptoms from sepsis in mice, increasing cardiac function and decreasing inflammatory responses.
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