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Filtered Search Results
Medchemexpress LLC Ruboxistaurin mesylate | 192050-59-2 | 99.9% | 564.65 g·mol⁻1 | C29H32N4O6S | 1 MG
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Ruboxistaurin mesylate is an orally active, selective ATP-competitive inhibitor of protein kinase C beta (PKCβ) used in research on diabetic vascular complications, retinal microcirculation, and cardiac models. It is supplied as an orange-red solid with high purity and is commonly prepared in DMSO for in vitro assays.
- Orally active, selective PKCβ inhibitor.
- High purity (≈99.9%) suitable for biochemical and cell-based assays.
- Molecular weight 564.65 g·mol⁻1; formula C29H32N4O6S.
- Soluble in DMSO at 50 mg/mL; may require ultrasonication.
- Store sealed at 4°C; in solution store at -80°C for long-term stability.
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Medchemexpress LLC Gemifloxacin mesylate | 210353-53-0 | MFCD08277637 | 99.59% | 1 ML
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Gemifloxacin mesylate is an orally active, broad-spectrum quinolone antibacterial antibiotic. It works by inhibiting DNA synthesis through the inhibition of DNA gyrase and Topoisomerase IV activities. It has been utilized in the research of respiratory tract infections.
- Inhibits DNA synthesis by targeting DNA gyrase and Topoisomerase IV activities
- Exhibits potent antibacterial activities against gram-positive bacteria in vitro, particularly Streptococci and Staphylococci
- Higher antibacterial activity than Moxifloxacin against Streptococcus pneumoniae with a MIC90 of 0.06 μg/mL
- Highly potent antibacterial activity against Penicillin-resistant strains of S. pneumoniae with a MIC90 of 0.03 μg/mL
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Medchemexpress LLC FIRMONERTINIB MESYL 10MM/1ML
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FIRMONERTINIB MESYL 10MM/1ML
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Medchemexpress LLC 4-Quinolinol | 611-36-9 | 99.9% | C9H7NO | 1 ML
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4-Quinolinol (Kynurine) is a quinoline derivative that modulates tryptophan metabolism through the Kynurine pathway, involved in neuroprotective effects. It promotes tumor cell survival and motility by suppressing antitumor immune responses, particularly active in human brain tumors where AhR activation enhances TDO expression, producing more kynurine and kynurinic acid.
- Quinoline derivative
- Modulates tryptophan metabolism
- Involved in neuroprotective effects
- Promotes tumor cell survival and motility
- Suppresses antitumor immune responses
- Soluble in DMSO (100 mg/mL)
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Medchemexpress LLC SKA-31 | 40172-65-4 | 99.7% | 200.27 | 100 MG
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SKA-31 | 40172-65-4 | 99.7% | 200.27 | 100 MG
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Medchemexpress LLC 3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl-4,4,4-trifluoro-1-butanesulfonate | 406205-74-1 | 98.6% | 453.36 g·mol⁻1 | C18H13F6NO4S | 50 MG
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BAY 59-3074 is a cannabinoid CB1/CB2 receptor partial agonist originally reported by Bayer. It has been characterized in vitro and in vivo for analgesic and antihyperalgesic effects and is used in research to probe cannabinoid receptor pharmacology.
- Selective CB1/CB2 receptor partial agonist (human CB1 Ki = 48.3 nM; human CB2 Ki = 45.5 nM).
- High purity: 98.6%.
- Chemical formula C18H13F6NO4S; molecular weight 453.36 g·mol⁻1.
- Solid, white to off-white physical form, suitable for laboratory handling.
- Documented in peer-reviewed literature and product datasheets for research use.
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Medchemexpress LLC 5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine | 2095417-73-3 | C31H32N2O9 | 25 MG
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5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs exhibit broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibition of DNA synthesis and induction of apoptosis.
- Purine nucleoside analog
- Broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
- Relevant for cancer research
- Related to oligonucleotides and nucleoside analogs
- Applicable to various cancers
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Medchemexpress LLC (S,R,S)-AHPC-amido-C7-acid | 2172819-76-8 | 98.71% | 600.77 | 500 MG
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(S,R,S)-AHPC-amido-C7-acid incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. It can be used to design PROTACs. This product is for research use only.
- Incorporates a VHL ligand for E3 ubiquitin ligase
- Includes a PROTAC linker
- Used to design PROTACs
- Relevant for cancer and cancer targeted therapy research
- Classified as E3 ligase ligand-linker conjugates
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Medchemexpress LLC 6-(2-(4-((4-fluorophenyl)phenylmethylidene)piperidin-1-yl)ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one | 93076-89-2 | MFCD00055114 | ≥98.0% | 459.58 g/mol | C27H26FN3OS | 25 MG
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R 59-022 is a small-molecule research reagent that inhibits diacylglycerol kinase (DGK) and functions as a 5-HT receptor antagonist. It is used to modulate protein kinase C (PKC) activation and diacylglycerol-dependent signaling in biochemical and cell-based studies. Chemical identifiers include CAS 93076-89-2, formula C27H26FN3OS, and molecular weight ≈459.58 g/mol.
- Potent DGK inhibitor (reported IC50 ≈ 2.8 μM).
- Modulates PKC activation and diacylglycerol signaling.
- Used in platelet aggregation and cellular signaling studies.
- High reported purity (≥98%).
- Provided in small research quantities suitable for assay development.
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Medchemexpress LLC Ro 31-9790 (GI4747) | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 50 MG
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Ro 31-9790 is a synthetic matrix metalloproteinase (MMP) inhibitor used as a research reagent to probe MMP activity, protease-mediated ectodomain shedding, and related cellular pathways. It is supplied as a high-purity solid for laboratory studies and includes handling and storage recommendations to preserve stability.
- High purity, suitable for biochemical and cellular assays.
- Molecular weight 315.41 g/mol and formula C15H29N3O4 for compound identification.
- Off-white to light yellow solid appearance for easy visual confirmation.
- Recommended storage at 4°C; protect from light and store under inert gas; in solvent, store at -80°C (6 months) or -20°C (1 month).
- Soluble in DMSO with supplier-provided concentration guidance for assay preparation.
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Medchemexpress LLC 4,7,10,13,16-pentaoxanonadecane-1,19-diamine | 869308-34-9 | 97.5% | 308.41 g/mol | C14H32N2O5 | 25 MG
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4,7,10,13,16-pentaoxanonadecane-1,19-diamine is a polyethylene glycol (PEG)-based diamine linker provided for laboratory research and chemical synthesis. It is a colorless to light-yellow liquid (MW 308.41 g/mol, CAS 869308-34-9) whose two terminal primary amines and ether-rich backbone make it suitable as a bifunctional spacer in bioconjugation and polymer modification. Recommended storage at low temperature preserves stability and performance.
- Bifunctional primary amine termini for crosslinking and conjugation.
- Ether-rich PEG backbone provides flexibility and solubility in polar solvents.
- High reported purity (97.45% by LCMS) supports reproducible chemistry.
- Liquid form simplifies handling and solution preparation.
- Cold-storage stability extends usable shelf life when stored as recommended.
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Medchemexpress LLC SKA-31 25 mg
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SKA-31 25MG
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Medchemexpress LLC TL02-59 5 mg
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TL02-59 5MG
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Medchemexpress LLC LM11A-31 DIHYDROCHL 100 mg
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LM11A-31 DIHYDROCHL 100MG
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Medchemexpress LLC 4 7-DIHYDROXYCOUMARI 10MM/1ML
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4 7-DIHYDROXYCOUMARI 10MM/1ML
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