Quinolines and derivatives
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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Mefloquine hydrochloride European Pharmacopoeia (EP) Reference Standard | 51773-92-3 | MFCD00797519 |
Mefloquine hydrochloride European Pharmacopoeia (EP) Reference Standard | Mol Wt: 414.77 | 51773-92-3 | MFCD00797519 |
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GRAINGER INC 7-METHYLQUINOLINE 25G
502781389 7-METHYLQUINOLINE 25G
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Ambeed 1Methylpyrrolidine
1-Methylpyrrolidine, 120-94-5, 95%
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Ambeed 7Bromo1 2dihydroisoquinolin3 4
7-Bromo-1,2-dihydroisoquinolin-3(4H)-one, 943751-93-7, 95%
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Ambeed OC614 2 3Butanedione 2 3di
(OC-6-14)-[[2,3-Butanedione 2,3-di(oximato-κN)](1-)][2,3-butanedione 2,3-di(oxime-κN)]dichlorocobalt, 23638-66-6, 98%
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Ambeed Methyl 2 3dichloroquinoxaline6
Methyl 2,3-dichloroquinoxaline-6-carboxylate, 108258-54-4, 98%
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Medchemexpress LLC ACT-1004-1239 | 2178049-58-4 | 98.8% | C27H28F2N6O3 | 50 MG
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ACT-1004-1239 is a potent, selective, and orally active CXCR7 antagonist with an IC50 value of 3.2 nM. It promotes oligodendrocyte precursor cell (OPC) differentiation by increasing CXCL12 levels. In animal models, it has been shown to reduce disease severity in myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) and increase myelination in Cuprizone-induced demyelination models. This product is for research use only.
- Potent, selective, and orally active CXCR7 antagonist
- IC50 value of 3.2 nM
- Promotes oligodendrocyte precursor cell (OPC) differentiation
- Increases CXCL12 levels
- Reduces disease severity in MOG-induced experimental autoimmune encephalomyelitis (EAE) in animal models
- Increases myelination in Cuprizone-induced demyelination models
- For research use only
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Ambeed 4 4 Bipyridine
4,4'-Bipyridine, 553-26-4, 98%
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Ambeed 3 2 9HFluoren9yl methoxy ca
3-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)propanoic acid, 1654740-73-4, 97%
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Medchemexpress LLC Mal-amido-PEG12-acid | 2378428-27-2 | C34H60N2O17 | 50 MG
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Mal-amido-PEG12-acid is a PEG-based PROTAC linker suitable for synthesizing PROTACs. It functions by connecting two distinct ligands, one targeting an E3 ubiquitin ligase and the other for the specific target protein, allowing for the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Can be used in the synthesis of PROTACs.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
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Medchemexpress LLC 3,6,9-trioxa-12-azaheptadecan-17-oic acid, folate conjugate | 710323-40-3 | 99.7% | 615.64 | C27H37N9O8 | 10 MG
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Folate-PEG3-amine is a cleavable three-unit polyethylene glycol linker bearing a folate moiety, used for targeted conjugation and antibody-drug conjugate synthesis. It provides a hydrophilic spacer with an amine for coupling to drugs or biomolecules.
- cleavable three-unit PEG spacer
- folate targeting motif for receptor-mediated delivery
- primary amine functional group for easy coupling
- high purity suitable for research applications
- hydrophilic spacer to improve solubility and reduce aggregation
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Medchemexpress LLC Leucomycin | 1392-21-8 | 200 MG
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Leucomycin (Kitasamycin) is an orally active macrolide antibiotic derived from *Streptomyces kitasatoensis*. It exhibits broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae, and some larger viruses.
- Orally active macrolide antibiotic
- Derived from *Streptomyces kitasatoensis*
- Exhibits broad-spectrum antibacterial activities
- Targets gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae, and some larger viruses
- Appearance: solid
- Color: white to off-white
- In vitro solubility: 110 mg/mL in DMSO (requires ultrasonic); < 0.1 mg/mL in H2O (insoluble)
- IC50 & Target: macrolide
- Melting point: 128-145°C
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Medchemexpress LLC 3,6,9,12,15,18,21,24-octaoxapentacosan-1-amine | 869718-81-0 | MFCD13184961 | 98.0% | 383.48 g/mol | C17H37NO8 | 10 G
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m-PEG8-Amine is a monomethyl polyethylene glycol (PEG8) primary amine used as a cleavable linker in antibody-drug conjugate (ADC) synthesis and other bioconjugation applications. It provides an eight-unit PEG spacer with a terminal primary amine for conjugation chemistry, and is supplied at high purity for research use.
- Cleavable PEG8 linker suitable for ADC and bioconjugation chemistry.
- Provides an eight-unit (PEG8) flexible spacer with a terminal primary amine.
- High purity suitable for research use: 98.0%.
- Molecular weight approximately 383.48 g/mol; formula C17H37NO8.
- SMILES COCCOCCOCCOCCOCCOCCOCCOCCN; compatible with common conjugation reactions.
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Medchemexpress LLC 3,6,9,12,15,18-Hexaoxanonadecan-1-amine | 184357-46-8 | ≥97.0% | 295.37 | C13H29NO6 | 250 MG
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m-PEG6-Amine (3,6,9,12,15,18-Hexaoxanonadecan-1-amine, CAS 184357-46-8) is a methoxy-terminated polyethylene glycol (PEG6) primary amine linker used as a flexible, hydrophilic spacer for assembling PROTAC molecules and as a cleavable linker in antibody-drug conjugates (ADCs). The compound has formula C13H29NO6, molecular weight 295.37, and typical purity ≥97.0%.
- Provides a six-unit polyethylene glycol spacer to improve solubility and flexibility.
- Terminal primary amine enables straightforward conjugation chemistry for amide or carbamate coupling.
- Suitable for PROTAC and ADC synthesis as a cleavable, hydrophilic linker.
- High reported purity (≥97.0%) suitable for research applications.
- Recommended storage: 4°C protected from light; in solvent, store at -80°C (6 months) or -20°C (1 month) when protected from light.
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TARGETMOL CHEMICALS INC LY2940094 5MG
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Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. LY2940094 (LY-2940094) decreases ethanol self-administration in animal models. LY2940094 is an effective selective and orally available nociceptin receptor antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM). purity: 99%
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