Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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2,026 – 2,040 of 4,396 results

2,026

Medchemexpress LLC Azido-PEG23-amine | 2172677-19-7 | 1023457 | 99.9% | C48H98N4O23 | 25 MG

Azido-PEG23-amine is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a versatile click chemistry reagent due to its azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.

PEG-based PROTAC linker
Used in PROTAC synthesis
Functions as a click chemistry reagent
Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Reacts with alkyne-containing molecules
Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
Reacts with DBCO or BCN group-containing molecules

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2,027

Medchemexpress LLC STING agonist-8 dihydrochloride | 2745723-90-2 | >98% | C41H48Cl2N14O4 | 25 MG

STING agonist-8 dihydrochloride, also known as compound 5-AB, is a potent Stimulator of Interferon Genes (STING) agonist with an EC50 of 27 nM in THP1-Dual KI-hSTING-R232 cells. This product is designated exclusively for research purposes, ideal for studying the STING pathway in innate immunity.

Potent STING agonist.
Supplied as a dihydrochloride salt, a white to off-white solid.
Soluble in DMSO at 5 mg/mL (5.74 mM) with sonication and heating.
Store at -20°C in a sealed container, protected from moisture.
Useful for immunology, inflammation, and drug discovery research.
Applied in in vitro and in vivo studies of STING activation.

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2,028

Ambeed Anthracen9ylmethanamine

Anthracen-9-ylmethanamine, 2476-68-8, 97%

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2,029

Ambeed R 5 S 1 2Dihydroxyethyl 3 4d

(R)-5-((S)-1,2-Dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one, 50-81-7, 98%

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2,030

Ambeed tertButyl 1 8diazaspiro 4.5 de

tert-Butyl 1,8-diazaspiro[4.5]decane-8-carboxylate, 937729-06-1, 95%

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2,031

Ambeed tertButyl 3 8diazabicyclo 3.2.

tert-Butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate, 149771-44-8, 96%

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2,032

Medchemexpress LLC Sulfo-ara-F-NMN | 1374663-29-2 | 99.4% | 25 MG

Sulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN) that selectively activates SARM1 and inhibits CD38 with an IC50 of approximately 10 μM. This compound stimulates intracellular cyclic ADP-ribose (cADPR) production and subsequently activates SARM1 to generate cyclic ADP-ribose, leading to non-apoptotic cell death. It is intended for research use only.

Mimetic of nicotinamide mononucleotide (NMN)
Selectively activates SARM1
Inhibits CD38 (IC50 around 10 μM)
Induces intracellular cyclic ADP-ribose (cADPR) production
Activates SARM1 to produce cyclic ADP-ribose
Induces non-apoptotic cell death
For research use only

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2,033

Medchemexpress LLC Quinine hydrochloride | 130-89-2 | MFCD00078498 | 99.8% | 360.88 | 1 ML

Quinine hydrochloride is an alkaloid derived from the bark of the cinchona tree, primarily known for its role as an anti-malaria agent. It also functions as a potassium channel inhibitor.

Acts as an anti-malaria agent
Inhibits WT mouse Slo3 (KCa5.1) channel currents
Suitable for laboratory centrifugation and storage

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2,034

AURUM PHARMATECH INC TERT-BUTYL N-METHYL-N-CARBA 1G

NC3454432 TERT-BUTYL N-METHYL-N-CARBA 1G

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2,035

eMolecules 1677-46-9 | 4-Hydroxy-1-methyl-2-quinolone | Combi-Blocks | MFCD00024052 | 175.187 | C10H9NO2 | 98.000 | Cn1c2ccccc2c(O)cc1=O | 1g | 267209374

4-Hydroxy-1-methyl-2-quinolone | Combi-Blocks | 1677-46-9 | MFCD00024052 | 175.187 | C10H9NO2 | 98.000 | Cn1c2ccccc2c(O)cc1=O | 1g | 267209374

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2,036

Medchemexpress LLC Indisulam | 165668-41-7 | MFCD00945325 | 99.8% | 385.85 | 200 MG

Indisulam (E 7070) is a carbonic anhydrase inhibitor with anticancer activity. This sulfonamide agent targets the G1 phase of the cell cycle, causing a blockade in the G1/S transition. It achieves this by inhibiting the activation of both CDK2 and cyclin E. Additionally, it targets splicing by inducing RBM39 degradation via recruitment to DCAF15.

Carbonic anhydrase inhibitor
Exhibits anticancer activity
Sulfonamide agent
Targets G1 phase of the cell cycle
Inhibits CDK2 and cyclin E activation
Induces RBM39 degradation
Involved in splicing modulation

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2,037

TARGETMOL CHEMICALS INC TD-198946 5MG

Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. TD-198946 a potent chondrogenic agent is a thienoindazole derivative. purity: 98%

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2,038

Medchemexpress LLC Pomalidomide-amido-C | 25MG

Pomalidomide-amido-C | 25MG

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2,039

Medchemexpress LLC Sulfo DBCO-amine | 2028284-70-8 | 99.0% | 25 MG

Sulfo DBCO-amine is an alkyl chain-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that possess Azide groups. PROTACs themselves consist of two distinct ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein, enabling selective degradation of target proteins through the intracellular ubiquitin-proteasome system.

Alkyl chain-based PROTAC linker.
Utilized in the synthesis of PROTACs.
Functions as a click chemistry reagent.
Contains a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC).
Enables selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
Suitable for cancer and cancer targeted therapy research.

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2,040

eMolecules EMOLECULES INC

5000841457 DICYCLOHEXYL2 6-DIMETHOXY 5G

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Quinolines and derivatives

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Medchemexpress LLC Azido-PEG23-amine | 2172677-19-7 | 1023457 | 99.9% | C48H98N4O23 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC STING agonist-8 dihydrochloride | 2745723-90-2 | >98% | C41H48Cl2N14O4 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sulfo-ara-F-NMN | 1374663-29-2 | 99.4% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Quinine hydrochloride | 130-89-2 | MFCD00078498 | 99.8% | 360.88 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Indisulam | 165668-41-7 | MFCD00945325 | 99.8% | 385.85 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC TD-198946 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pomalidomide-amido-C | 25MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sulfo DBCO-amine | 2028284-70-8 | 99.0% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More