Quinolines and derivatives

TARGETMOL CHEMICALS INC BEPRIDIL HYDROCHLORIDE 50MG

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Also available in 5 mg 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Bepridil hydrochloride (CERM 1978) is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX) sodium channels and cardiac sarcolemmal KATP channels. purity: 99%

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Medchemexpress LLC Amino-PEG7-amine | 332941-25-0 | 99.3% | C16H36N2O7 | 250 MG

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Amino-PEG7-amine is a PEG-based PROTAC linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs). These compounds are designed with two ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other for a target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is for research use only.

• PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Utilizes the intracellular ubiquitin-proteasome system
• Designed for selective degradation of target proteins

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Medchemexpress LLC Benzyl-PEG2-amine | 1268135-96-1 | C11H17NO2 | 250 MG

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Benzyl-PEG2-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are designed with two distinct ligands linked together; one ligand binds to an E3 ubiquitin ligase and the other targets a specific protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

• Functions as a PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Facilitates targeted protein degradation
• PROTACs utilize specific ligands for E3 ubiquitin ligase and target proteins

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Ambeed Methyl 6oxopiperidine2carboxyl

Methyl 6-oxopiperidine-2-carboxylate, 111479-60-8, 97%

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eMolecules​ Chem-Impex Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt 100mg 272386940 23033 0 000 92921-24-9 MFCD00054978 436 370 C16H17N2NaO9S

Chem-Impex Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt 100mg 272386940 23033 0 000 92921-24-9 MFCD00054978 436 370 C16H17N2NaO9S

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Sigma Aldrich Fine Chemicals Biosciences Ethyl lactate 98 fCC fG25KG

Ethyl lactate is a major volatile flavor compound identified in Chinese Luzhou-flavor type liquor.

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eMolecules​ 2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol | 6964-62-1 | MFCD08823776 | 50mg

Ambeed | 2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol | 50mg | 525100416 | A183021 | | 6964-62-1 | MFCD08823776 | 340.426 | C23H20N2O

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Medchemexpress LLC CP 339818 (hydrochloride) | 478341-55-8 | 99.6% | 340.89 | 1 MG

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CP 339818 hydrochloride is a non-peptide blocker of Kv1.3 (IC50 = 200 nM) and Kv1.4 channels. It also inhibits HCN channels with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl-), respectively. The compound exhibits significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. It can be utilized for studying the physiological functions of HCN and Kv channels.

• Non-peptide Kv1.3 and Kv1.4 channel blocker.
• Inhibits HCN channels (HCN1 and HCN4).
• Selectively blocks Kv1.3, inhibiting human T cell activation.
• Useful for studying physiological functions of HCN and Kv channels.
• Suppresses human T cell activation.
• Effectively blocks remaining outward potassium current in Kv2.1⁻/⁻ β cells.
• Inhibitory effect on HCN1 and HCN4 is weakened in low-concentration Cl- internal solution and is voltage-dependent.

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MOLPORT INC 2 5-DIMETHOXY-N- QUINOLIN- 2UM

NC3232342 2 5-DIMETHOXY-N- QUINOLIN- 2UM

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Apexbio Technology LLC KN-92 176708-42-2 200mg

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KN-92 is a structurally related but inactive analog of the CaMKII inhibitor KN-93 primarily utilized as a negative control compound in investigations of Ca2 /calmodulin-dependent kinase II (CaMKII) function Unlike KN-93 KN-92 does not effectively interfere with the binding of calmodulin (CaM) to the CaMKII enzyme and does not demonstrate substantial inhibition of CaMKII catalytic activity As a molecular control KN-92 allows researchers to distinguish between CaMKII-specific inhibitory effects and potential non-specific cellular influences when employing KN-93 in experimental models KN-93 itself selectively interacts with the CaM-binding region of CaMKII impeding enzyme activity implicated in cellular responses such as calcium-induced calcium release in cardiac cells histamine-stimulated aminopyrine uptake in gastric parietal cells and calcium-dependent induction of HIF-1 in cancer cells