Quinolines and derivatives
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Filtered Search Results
=O)c2cccnc12 | 1g | 117530764](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00128114-117530764.PNG-250.jpg)
eMolecules 19746-57-7 | 8-Ethoxy-5-nitroquinoline | Combi-Blocks | MFCD00777819 | 218.212 | C11H10N2O3 | 98.000 | CCOc1ccc([N+]([O-])=O)c2cccnc12 | 1g | 117530764
8-Ethoxy-5-nitroquinoline | Combi-Blocks | 19746-57-7 | MFCD00777819 | 218.212 | C11H10N2O3 | 98.000 | CCOc1ccc([N+]([O-])=O)c2cccnc12 | 1g | 117530764
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Medchemexpress LLC Quinidine 15 dihyd 1g | 1G
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Quinidine 15 dihyd 1g | 1G
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Medchemexpress LLC Quinine sulfate hydrate | 6119-70-6 | 99.97% | 409.48 | 25 G
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Quinine sulfate hydrate is an orally active alkaloid extracted from cinchona bark, primarily used in anti-malarial studies. It also functions as a potassium channel inhibitor, inhibiting WT mouse Slo3 (KCa5.1) channel currents.
- Orally active alkaloid
- Extracted from cinchona bark
- Used in anti-malarial studies
- Potassium channel inhibitor
- Inhibits WT mouse Slo3 (KCa5.1) channel currents
- Inhibits DENV proliferation and reduces viral RNA/protein levels
- Shows tumor-suppressing effects
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Medchemexpress LLC Mefloquine (Standard) | 53230-10-7 | 378.31 | 1 G
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent, and also functions as an anti-SARS-CoV-2 entry inhibitor. Mefloquine is a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. It can be utilized for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard grade
- Reference standard supplied assay
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- Suitable for various research and analytical applications
- Potential for malaria, systemic lupus erythematosus, and cancer research
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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.4% | 50 G
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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent and a potent, orally active, selective cytochrome P450db inhibitor. It also acts as a K+ channel blocker with an IC50 of 19.9 μM and can induce apoptosis. This product is suitable for malaria research and has shown cytotoxicity against MES-SA cells, as well as effects on the PTZ-induced seizure threshold.
- Acts as an antiarrhythmic agent
- Potent, orally active, selective cytochrome P450db inhibitor
- Functions as a K+ channel blocker
- Capable of inducing apoptosis
- Applicable for malaria research
- Exhibits cytotoxicity against MES-SA cells
- Affects PTZ-induced seizure threshold
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Sigma Aldrich Fine Chemicals Biosciences Quinine suitable for fluorescence, anhydrous, >=98.0% (dried material, NT) | 130-95-0 | MFCD00198096 | 100G
Quinine suitable for fluorescence, anhydrous, >=98.0% (dried material, NT) | Purity: >=98.0% (dried material, NT) | Mol Wt: 324.42 | 130-95-0 | MFCD00198096 | 100G
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Medchemexpress LLC Cinchonine ((8R,9S)-cinchonine) | 118-10-5 | MFCD00064372 | 99.7% | 294.39 | C19H22N2O | 500g
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Cinchonine is a natural compound present in Cinchona bark with antimalarial antitumor anti-inflammatory anti platelet-aggregation and anti-obesity properties Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3 Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1]
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Medchemexpress LLC Cinchonidine | 485-71-2 | 99.6% | 294.39 | 10 G
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Cinchonidine (α-Quinidine) is a cinchona alkaloid found in *Cinchona officinalis* and *Gongronema latifolium*. It is a building block used in asymmetric synthesis in organic chemistry. It acts as a weak inhibitor of serotonin transporter (SERT) and exhibits antimalarial activities.
- Source: Cinchona alkaloid found in *Cinchona officinalis* and *Gongronema latifolium*.
- Application: Building block in asymmetric synthesis in organic chemistry.
- Biological activity: Weak inhibitor of serotonin transporter (SERT).
- Pharmacological effect: Antimalarial activities.
- Appearance: Solid, white to off-white.
- Storage: Room temperature for continental US shipping; 4°C, protected from light, stored under nitrogen.
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Medchemexpress LLC Hydroquinidine | 1435-55-8 | 100.0% | 25 G
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Hydroquinidine, also known as Dihydroquinidine, is a potent ion channel blocker with demonstrated anti-cancer activity against colon, pancreatic, and hepatocellular cancer cells. It is also known to prolong the QT interval and exhibit antiarrhythmic efficacy.
- Potent ion channel blocker
- Demonstrates strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells
- Prolongs the QT interval
- Exhibits antiarrhythmic efficacy
- Molecular formula: C20H26N2O2
- Molecular weight: 326.44
- Appearance: White to off-white solid
- For research use only
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Medchemexpress LLC Cinchonine | 118-10-5 | MFCD00064372 | 99.7% | 294.39 | C19H22N2O | 10g
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Cinchonine is a natural compound present in Cinchona bark with antimalarial antitumor anti-inflammatory anti platelet-aggregation and anti-obesity properties Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3 Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1]
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Sigma Aldrich Fine Chemicals Biosciences Quinine suitable for fluorescence, anhydrous, >=98.0% (dried material, NT) | 130-95-0 | MFCD00198096 | 5G
Quinine suitable for fluorescence, anhydrous, >=98.0% (dried material, NT) | Purity: >=98.0% (dried material, NT) | Mol Wt: 324.42 | 130-95-0 | MFCD00198096 | 5G
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Medchemexpress LLC Quinine hemisulfate hydrate | 207671-44-1 | 99.4% | 1 G
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Quinine hemisulfate hydrate is an alkaloid derived from the bark of the cinchona tree, acting as an anti-malaria agent. It is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV, with an IC50 of 169 μM.
- Alkaloid derived from the bark of the cinchona tree.
- Acts as an anti-malaria agent.
- Potassium channel inhibitor.
- Inhibits WT mouse Slo3 (KCa5.1) channel currents with an IC50 of 169 μM.
- For research use only.
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Medchemexpress LLC Quinine hydrochloride dihydrate | 6119-47-7 | 99.7% | 1 ML
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Quinine hydrochloride dihydrate (Qualaquin) is an orally active anti-malarial agent and a potassium channel inhibitor. It inhibits WT mouse Slo3 (KCa5.1) channel currents with an IC50 of 169 μM.
- Used in anti-malarial studies.
- Inhibits WT mouse Slo3 (KCa5.1) channel currents.
- Shows antiviral activity against DENV (Dengue virus) in human HepG2 cell lines.
- May have tumor-suppressing effects on skin cancer in Swiss albino mice.
- Impacts the antioxidant defense system in rat testicular tissue.
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Selleck Chemical LLC Resiquimod
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Resiquimod (R-848 S28463) is an immune response modifier that acts as a potent TLR 7/TLR 8 agonist that induces the upregulation of cytokines such as TNF- IL-6 and IFN- Resiquimod reduces hepatitis C virus (HCV) infection Phase 2
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TARGETMOL CHEMICALS INC Imiquimod 500MG
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Also available in 1 g, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist. Purity 99.66%
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