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Filtered Search Results
Enzo Life Sciences R-848, (25mg), CAS Number: 144875-48-9
Ligand for TLR7 and TLR8. R-848 is a selective ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Potent antitumor and antiviral compound. Stimulates antibody secretion, cytokine production, protection from apoptosis and CD80 upregulation. Alternative Name: 4-Amino-2-(ethoxymethyl)-a,a-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol. S 28463, Resiquimod, Formula: C17H22N4O2. MW: 314.4. CAS Number: 144875-48-9. Purity: ≥98% (HPLC). Appearance: White to off-white solid. Solubility: Soluble in DMSO, dichloromethane, 100% or 5% methanol; poorly soluble in acetonitrile or ethyl acetate. Long Term Storage: -20°C
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Apexbio Technology LLC Mefloquine hydrochloride 51773-92-3 10mM (in 1mL DMSO)
Mefloquine hydrochloride is a quinoline-based antimalarial compound structurally related to quinidine with demonstrated inhibitory effects on Plasmodium falciparum It functions primarily through modulation of potassium ion channels displaying an IC50 around 1 M against KvLQT1/minK channel currents and approximately 5 6 M against HERG channel currents Research indicates that mefloquine induces cellular oxidative stress modulating intracellular signaling pathways including Akt phosphorylation ERK JNK and AMPK in vitro Current studies also explore its potential cytotoxic activity toward cancer cell lines and evaluate effectiveness against urinary schistosomiasis in phase 2 clinical trials
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Medchemexpress LLC Quinidine hydrochloride monohydrate | 6151-40-2 | 99.97% | 100 MG
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Quinidine hydrochloride monohydrate is an anti-arrhythmic agent that also acts as a potent blocker of K+ channels. It is intended for research use only.
- Potent K+ channel blocker.
- Aids in electrophysiological research.
- Available in solid and solution forms for various experimental needs.
- Comes with detailed documentation for quality assurance.
- Referenced in numerous scientific publications.
- Offers diverse applications for in vitro and in vivo studies.
- Easily soluble in common laboratory solvents.
- Supports accurate dosage calculations for experimental protocols.
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AdipoGen Quinine HCl dihydrate
Chemical. CAS 6119-47-7. Formula C20H24N2O2 . HCl . 2H2O. MW BD9837. Quinine hydrochloride dihydrate is isolated from the cinchona tree?s bark, is characterized by a bitter taste and shows antipyretic fever-reducing, anti-malarial, analgesic painkilling, anti-viral and anti-inflammatory properties. Quinine also possesses, at high concentrations, antibacterial properties, which suggests it has potential as an antimicrobial adjuvant. It is believed to impede the activity of enzymes associated with nucleic acid and protein biosynthesis and act as an antagonist for specific neurotransmitters, including serotonin. Quinine acts as a competitive inhibitor of monoamine oxidase MAO, an enzyme that removes neurotransmitters from the brain and a general potasssium channel blocker. Quinine is a flavor component of tonic water and bitter lemon drink mixers.
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eMolecules 3413-58-9 | Medchem Express | Ethylhydrocupreine (hydrochloride) | 25mg | 673358916 | HY-136429A | 376.93 | C21H29ClN2O2
Ambeed | 8-Bromo-6-chloro-3-methylimidazo[12-a]pyrazine | 50mg | 521478261 | A760598 | 84066-11-5 | MFCD22576309 | 246.490 | C7H5BrClN3
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eMolecules Building Block Tool
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000270069 CINCHONINE 100G
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Medchemexpress LLC Hydroquinidine | 1435-55-8 | 99.97% | 5 G
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Hydroquinidine (Dihydroquinidine) is a potent ion channel blocker that exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells. It also prolongs the QT interval and demonstrates antiarrhythmic efficacy.
- Potent ion channel blocker
- Strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells
- Prolongs the QT interval
- Antiarrhythmic efficacy
- For research use only
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Medchemexpress LLC CINCHONIDINE STANDA 50 mg
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CINCHONIDINE STANDA 50MG
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Medchemexpress LLC CINCHONIDINE STANDA 100 mg
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CINCHONIDINE STANDA 100MG
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Medchemexpress LLC Imiquimod hydrochloride | 99011-78-6 | 99.8% | 100 MG
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Imiquimod hydrochloride (R 837 hydrochloride) is an immune response modifier and a selective toll-like receptor 7 (TLR7) agonist. It exhibits antiviral and antitumor effects in vivo and can be used for the research of external genital, perianal warts, cancer, and COVID-19.
- Exhibits antiviral effects in vivo
- Exhibits antitumor effects in vivo
- Selective TLR7 agonist
- Used in research for external genital, perianal warts, cancer, and COVID-19
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Ambeed AMBEED
5000868600 RESIQUIMOD 100MG
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TARGETMOL CHEMICALS INC Quinidine hydrochloride monohy
Also available in 1 mL, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Quinidine hydrochloride monohydrate is an optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. It prolongs cellular action potential and decreases automaticity. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission. Purity 94.72%
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eMolecules 51773-92-3 | Medchem Express | Mefloquine (hydrochloride) | 100mg | 446268425 | HY-17437A | MFCD22208579 | 414.78 | C17H17ClF6N2O
Medchem Express | Mefloquine (hydrochloride) | 100mg | 446268425 | HY-17437A | 51773-92-3 | MFCD22208579 | 414.780 | C17H17ClF6N2O
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Medchemexpress LLC Cinchonidine (α-Quinidine) | 485-71-2 | 99.6% | 294.39 | 100 G
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Cinchonidine (α-Quinidine) is a cinchona alkaloid found in *Cinchona officinalis* and *Gongronema latifolium*. It is a building block used in asymmetric synthesis in organic chemistry. It acts as a weak inhibitor of the serotonin transporter (SERT) and exhibits antimalarial activities.
- Derived from *Cinchona officinalis* and *Gongronema latifolium*
- Used as a building block in asymmetric synthesis
- Weak inhibitor of the serotonin transporter (SERT)
- Exhibits antimalarial activities
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Medchemexpress LLC Mefloquine (Standard) | 53230-10-7 | MFCD00869324 | 378.31 | 100 MG
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. This analytical standard grade compound is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist.
- Used for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard grade for qualitative, quantitative, and methodological research experiments.
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