Quinolines and derivatives
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Filtered Search Results
Aobchem 1-Phenyl-1H-imidazole-2-carbaldehyde | ≥95% | CAS 6002-15-9 | C10H8N2O | 250mg
1-Phenyl-1H-imidazole-2-carbaldehyde | ≥95% | CAS 6002-15-9 | C10H8N2O | 250mg
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Aobchem 5-(Ethylthio)thiophene-2-carbonitrile | 95% | CAS 1216020-52-8 | C7H7NS2 | 500mg
5-(Ethylthio)thiophene-2-carbonitrile | 95% | CAS 1216020-52-8 | C7H7NS2 | 500mg
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Medchemexpress LLC SF1670 200 mg
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SF1670 200MG
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Medchemexpress LLC CAPRYLOCAPROYL MACRO 200 mg
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CAPRYLOCAPROYL MACRO 200MG
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Medchemexpress LLC SRS16-86 1 mg
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SRS16-86 1MG
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Medchemexpress LLC IFOSFAMIDE 200 mg
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IFOSFAMIDE 200MG
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Medchemexpress LLC 1-NAPHTHALENEACETIC 200 mg
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1-NAPHTHALENEACETIC 200MG
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Medchemexpress LLC Amifostine | 20537-88-6 | 99.95% | 200 MG
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Amifostine (WR2721) is a broad-spectrum cytoprotective and radioprotective agent that selectively protects normal tissues from damage. It is a potent inducer of HIF-α1 and p53, and protects cells by scavenging oxygen-derived free radicals.
- Selectively protects normal tissues from radiation and chemotherapy damage
- Potent hypoxia-inducible factor-α1 (HIF-α1) inducer
- Potent p53 inducer
- Protects cells by scavenging oxygen-derived free radicals
- Reduces renal toxicity
- Exhibits antiangiogenic action
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Medchemexpress LLC VARI FLUOR 555 CARBO 5 mg
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VARI FLUOR 555 CARBO 5MG
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Apexbio Technology LLC DIMENHYDRINATE-200MG
Dimenhydrinate (CAS No 523-87-5) is a compound frequently studied in the field of pharmacology for its properties as an antihistamine and antiemetic agent Originating as a combination of diphenhydramine and 8-chlorotheophylline its mechanism of action involves the antagonism of H1 histamine receptors and modulating neural pathways in the vestibular system providing relief from motion sickness and nausea In vitro activity of dimenhydrinate is observed within the nanomolar to low micromolar range It is commonly utilized in various cell models and animal studies to explore its pharmacokinetics and pharmacodynamics as well as in drug screening applications to evaluate its efficacy and safety profiles Experimental concentrations typically depend on the specific research design
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Apexbio Technology LLC FLUOROTHYL-200MG
Fluorothyl (CAS No 333-36-8) is a compound predominantly utilized in the field of neurological research originating from the study of fluorinated ethers Its mechanism of action involves the disruption of neural activity through competitive antagonism of GABA A receptors which can initiate seizure activity for the purpose of studying epileptogenesis and anticonvulsant testing In vitro activity is observed in the nanomolar to low micromolar range making it highly potent for research applications Common applications include studies using neuronal cell models and animal studies particularly rodents to evaluate anticonvulsant drugs and understand seizure pathways Experimental concentrations typically depend on the specific research design and desired outcomes Fluorothyl contributes significantly to the understanding of neuronal excitability and the development of therapeutic agents targeting neurological disorders
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Apexbio Technology LLC PENDIMETHALIN-200MG
Pendimethalin (CAS No 40487-42-1) is a pre-emergent herbicide widely used in agricultural research to study its effects on weed control Originating from the dinitroaniline chemical family its primary mechanism of action involves the inhibition of microtubule assembly preventing cell division in target plant cells In vitro studies have demonstrated that its activity generally falls within nanomolar to low micromolar ranges making it effective in disrupting cellular processes at relatively low concentrations Additionally Pendimethalin is commonly utilized in various cell models and animal studies to evaluate its efficacy and toxicity These studies provide insight into its potential environmental impact and guide the development of new agrochemical formulations Experimental concentrations typically depend on the specific research design Overall Pendimethalin remains a critical compound in herbicide research contributing to advancements in sustainable agricultural practices
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Apexbio Technology LLC Olmutinib (HM61713, BI 1482694) 1353550-13-6 200mg
Olmutinib (HM61713 BI 1482694 CAS 1353550-13-6) is an irreversible mutant-selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase It covalently binds to a cysteine residue near the EGFR kinase domain particularly targeting mutant forms such as L858R/T790M and exon 19 deletion In cellular assays Olmutinib demonstrated potent inhibition of EGFR signaling in NSCLC cell lines H1975 (L858R/T790M GI50 9 2 nM) and HCC827 (exon 19 deletion GI50 10 nM) while showing low activity against wild-type EGFR cell lines It exhibits prolonged inhibitory effects ( 24 h) on EGFR activity and demonstrates in vivo antitumor efficacy in xenograft models without significant adverse effects Olmutinib serves as a tool for studying third-generation EGFR TKI resistance mechanisms in NSCLC
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Medchemexpress LLC Hypoxystat | 2414508-40-8 | 99.28% | 367.40 | 200 MG
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Hypoxystat | 2414508-40-8 | 99.28% | 367.40 | 200 MG
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Medchemexpress LLC Matrine | 519-02-8 | 98.0% | 248.37 | 200 MG
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Matrine (Matridin-15-one) is an alkaloid found in plants of the *Sophora* genus. It acts as an agonist for kappa opioid receptor and u-receptor, and exhibits a range of pharmacological properties, including anti-cancer, anti-oxidative stress, anti-inflammatory, and anti-apoptosis effects. It holds potential for research into diseases such as human non-small cell lung cancer, hepatoma, papillary thyroid cancer, and acute kidney injury (AKI).
- Acts as a kappa opioid receptor and u-receptor agonist.
- Demonstrates anti-cancer effects.
- Possesses anti-oxidative stress properties.
- Exhibits anti-inflammatory effects.
- Has anti-apoptosis effects.
- Potential for research in human non-small cell lung cancer, hepatoma, papillary thyroid cancer, and acute kidney injury (AKI).
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