Quinolines and derivatives
Aobchem 2-Methoxy-8-quinolinecarboxaldehyde | ≥95% | CAS 885687-67-2 | C11H9NO2 | 250mg
2-Methoxy-8-quinolinecarboxaldehyde | ≥95% | CAS 885687-67-2 | C11H9NO2 | 250mg
eMolecules 79710-86-4 | Tetrahydrofuran-3-carbaldehyde | Oakwood Chemical | MFCD02101976 | 100.117 | C5H8O2 | 95.000 | O=CC1CCOC1 | 250mg | 812208378
Tetrahydrofuran-3-carbaldehyde | Oakwood Chemical | 79710-86-4 | MFCD02101976 | 100.117 | C5H8O2 | 95.000 | O=CC1CCOC1 | 250mg | 812208378
Aobchem 2 2-Difluoroethylmethane sulfonate | ≥95% | CAS 163035-65-2 | C3H6F2O3S | 500mg
2 2-Difluoroethylmethane sulfonate | ≥95% | CAS 163035-65-2 | C3H6F2O3S | 500mg
Aobchem 3-Fluoro-5-(morpholine-4-carbonyl)phenylboronic acid | ≥97% | CAS 874219-40-6 | C11H13BFNO4 | 5g
3-Fluoro-5-(morpholine-4-carbonyl)phenylboronic acid | ≥97% | CAS 874219-40-6 | C11H13BFNO4 | 5g
Apexbio Technology LLC Apixaban 503612-47-3 200mg
Apixaban (CAS 503612-47-3) is a highly selective reversible inhibitor of coagulation Factor Xa with Ki values of 0 08 nM and 0 17 nM for human and rabbit enzymes respectively By targeting Factor Xa a central serine protease in the coagulation cascade apixaban effectively impedes thrombin generation and subsequent clot formation In vitro apixaban prolongs coagulation parameters in human plasma at submicromolar concentrations and demonstrates potent antithrombotic activity across multiple animal models With favorable pharmacokinetics including high oral bioavailability and low clearance in preclinical studies apixaban serves as a valuable tool for investigating coagulation mechanisms and evaluating anticoagulant strategies
Aobchem 2 4-Dimethylthiophene-3-carbaldehyde | ≥97% | CAS 63826-85-7 | C7H8OS | 1g
2 4-Dimethylthiophene-3-carbaldehyde | ≥97% | CAS 63826-85-7 | C7H8OS | 1g
Aobchem 3 4-Dimethoxythiophene-2-carboxylic acid | ≥97% | CAS 113589-62-1 | C7H8O4S | 500mg
3 4-Dimethoxythiophene-2-carboxylic acid | ≥97% | CAS 113589-62-1 | C7H8O4S | 500mg
Aobchem 3 4-Dimethoxythiophene-2-carboxylic acid | ≥97% | CAS 113589-62-1 | C7H8O4S | 1g
3 4-Dimethoxythiophene-2-carboxylic acid | ≥97% | CAS 113589-62-1 | C7H8O4S | 1g
Aobchem 3 4-Dimethoxythiophene-2-carboxylic acid | ≥97% | CAS 113589-62-1 | C7H8O4S | 5g
3 4-Dimethoxythiophene-2-carboxylic acid | ≥97% | CAS 113589-62-1 | C7H8O4S | 5g
Medchemexpress LLC 4,6-diphenyl-1,2,3,4-tetrahydropyrimidine-2-thione | 6381-55-1 | MFCD00052358 | 98.6% | 266.36 g·mol⁻¹ | C16H14N2S | 200 MG
KKII5 is a small-molecule research inhibitor of lipoxygenase (LOX-1) used to study lipid peroxidation pathways; it has an IC50 of 19 μM and is supplied as a high-purity solid or as a DMSO solution for biochemical and cell-based assays.
- Inhibits lipoxygenase (LOX-1) with an IC50 of 19 μM.
- Inhibits lipid peroxidation in biochemical assays.
- High purity (98.6%) suitable for research use.
- Available as solid in multiple sizes and as a 10 mM solution in DMSO.
- Stable when stored as powder at -20 °C or 4 °C; in solvent at -80 °C or -20 °C.
- Molecular formula C16H14N2S; molecular weight 266.36 g·mol⁻¹.
- CAS number 6381-55-1 for unambiguous identification.
Apexbio Technology LLC StemRegenin 1 (SR1) 1227633-49-9 200mg
StemRegenin 1 (SR1 CAS 1227633-49-9) is a purine derivative that functions as an antagonist of the aryl hydrocarbon receptor (AhR) SR1 inhibits AhR signaling in CD34 hematopoietic progenitor cells with an IC50 value of approximately 127 nM Studies demonstrate that SR1 promotes the ex vivo expansion of CD34 cells significantly increasing both the number of CD34-expressing hematopoietic stem cells (HSCs) and their engraftment potential in immunodeficient mouse models Additionally SR1 enables differentiation and robust production of multiple dendritic cell subsets including plasmacytoid dendritic cells (pDCs) and BDCA1 /BDCA3 myeloid DCs from CD34 progenitors indicating its utility for dendritic cell research and hematopoietic stem cell biology
Medchemexpress LLC Propanoic acid, 2-hydroxy-, compound with dovitinib (lactate) | 692737-80-7 | MFCD23103506 | 99.8% | 482.51 g/mol | C24H27FN6O4 | 200 MG
Dovitinib lactate is the lactate salt of dovitinib, a multi-targeted tyrosine kinase inhibitor active at low nanomolar concentrations against FLT3, c-Kit, FGFR1/3, VEGFR1/2/3, and PDGFRα/β. Supplied as a light-yellow solid for research use, the product is provided in a 200 mg quantity and is intended for preclinical kinase and cell signaling studies.
- Multi-targeted tyrosine kinase inhibitor with low-nanomolar IC50s against FLT3, c-Kit, FGFR1/3, VEGFR1/2/3, and PDGFRα/β.
- Lactate salt form for improved handling and solubility.
- Molecular formula C24H27FN6O4; molecular weight 482.51 g/mol.
- Purity approximately 99.8% as reported by batch certificate of analysis.
- Soluble in DMSO (~25 mg/mL); use freshly opened DMSO due to hygroscopicity.
- Store sealed at 4°C and protect from moisture.
- For laboratory research use only; not for human or clinical use.
Medchemexpress LLC AS057278 | 402-61-9 | 99.76% | 126.11 | 200 MG
AS057278 is a potent, selective, orally active, and blood-brain barrier (BBB) penetrant non-peptidic D-amino acid oxidase (DAAO) inhibitor with an IC50 value of 0.91 μM and EC50 of 2.2-3.95 μM. It can normalize phencyclidine (PCP)-induced prepulse inhibition in mice and can be used for researching schizophrenia.
- Inhibits D-amino acid oxidase (DAAO)
- Potent, selective, orally active, and BBB penetrant
- Normalizes phencyclidine (PCP)-induced prepulse inhibition in mice
- Exhibits good pharmacokinetic effects in male Sprague-Dawley rats
- Appearance: solid, light yellow to light brown
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Apexbio Technology LLC Methacholine chloride 62-51-1 200mg
Methacholine chloride (CAS 62-51-1) is a synthetic choline ester that selectively activates muscarinic acetylcholine receptors predominantly the M3 subtype on airway smooth muscle cells By stimulating these receptors it induces bronchoconstriction and airway narrowing mimicking pathophysiological responses observed in airway hyperreactivity Methacholine chloride is frequently utilized in research to assess bronchial hyperresponsiveness (BHR) and measure airway hyperreactivity (AHR) in experimental models Clinically it supports the evaluation of asthma-like symptoms in patients with normal baseline pulmonary function
Medchemexpress LLC Mivavotinib monohydrochloride | 1952251-28-3 | 99.5% | 380.85 | C17H22ClFN6O | 10 MG
Mivavotinib monohydrochloride is the hydrochloride salt of mivavotinib, a potent, selective, reversible dual inhibitor of spleen tyrosine kinase (SYK) and fms-related tyrosine kinase 3 (FLT3) used for preclinical research. Supplied as a high-purity research chemical, it is used to probe SYK/FLT3 signaling and antitumor activity.
- Potent dual SYK and FLT3 inhibition, with reported IC50 values of 3.2 nM and 4.6 nM.
- High purity suitable for research (data sheet reported 99.50%).
- Available in small milligram pack sizes for preclinical experiments.
- Monohydrochloride salt form for improved stability and solubility compared with the free base.
- Molecular weight 380.85 and formula C17H22ClFN6O for accurate dosing calculations.