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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000586673 DIHYDROETHIDIUM SOL 500UL
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000724447 DIHYDREXIDINE HYDRO 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000693438 ETHIDIUM HOMODIMER 500UG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000693379 ETHIDIUM HOMODIMER 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000693201 DIHYDROETHIDIUM 1MG
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Selleck Chemical LLC Chelerythrine-E0124-25MG
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Chelerythrine (Toddaline Broussonpapyrine) is a potent selective antagonist of PKC with an IC50 of 0 66 M Chelerythrine also inhibits the BclXL-Bak BH3 peptide binding with an IC50 of 1 5 M Chelerythrine shows antitumor antidiabetic and anti-inflammatory activity
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Cambridge Isotope Laboratories 1 2 3 9-TetraCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
1 2 3 9-TetraCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
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Medchemexpress LLC Dihydrexidine (hydrochloride) | 137417-08-4 | MFCD01860859 | 98.9% | 303.78 g/mol | C17H18ClNO2 | 1 ML
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Dihydrexidine hydrochloride is a potent, selective full-efficacy D1/D5 dopamine receptor agonist used as a research reagent in pharmacology and neuroscience studies. The product is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) suitable for in vitro and preclinical applications.
- Potent, selective full-efficacy D1/D5 dopamine receptor agonist.
- Ready-to-use 10 mM solution in DMSO, 1 mL vial.
- High purity (~98.9%) as verified by LCMS.
- CAS number 137417-08-4 and molecular formula C17H18ClNO2.
- Molecular weight 303.78 g/mol.
- Intended for research use; follow SDS for handling and storage.
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Alkali Scientific Ethidium Bromide, Powder, 5 G
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Ethidium Bromide (EtBr), 5g, is a highly effective nucleic acid stain used in molecular biology for DNA visualization under UV light. As an intercalating agent, Ethidium Bromide binds to DNA and emits a fluorescent signal when exposed to ultraviolet light, allowing researchers to easily detect and analyze DNA bands in electrophoresis gels. This powder form is convenient for preparing various concentrations of staining solutions depending on experimental needs. Ethidium Bromide is widely used in genetic research, PCR analysis, and gel electrophoresis for visualizing DNA, making it a fundamental reagent in molecular and cellular biology laboratories.
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Cambridge Isotope Laboratories 1 2 3 9-TetraCDD (unlabeled) 25 ng/mL in nonane 0 2 mL
1 2 3 9-TetraCDD (unlabeled) 25 ng/mL in nonane 0 2 mL
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Medchemexpress LLC Propidium (iodide) | 25535-16-4 | 99.7% | 25 MG
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Propidium Iodide (PI) is a nuclear staining agent that binds to DNA, emitting red fluorescence upon embedding in double-stranded DNA. This analogue of ethidine bromide is commonly used in the detection of apoptosis or necrosis, and is often utilized in flow cytometry analysis due to its inability to pass through intact cell membranes, only staining nuclei in cells with damaged membranes.
- Emits red fluorescence upon DNA binding.
- Fluorescence wavelength: 493/617 nm.
- Wavelength after DNA mosaic: 536/635 nm.
- Permeates only damaged cell membranes.
- Targeted as a fluorescent dye for DNA/RNA synthesis.
- Emission maximum (Em): 615.
- Excitation maximum (Ex): 535.
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Alkali Scientific Ethidium Bromide, Powder, 25 G
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Ethidium Bromide (EtBr), 25g, is a powerful DNA stain used in molecular biology for visualizing nucleic acids in electrophoresis gels. Ethidium Bromide intercalates into DNA strands and emits fluorescent light when exposed to UV radiation, enabling clear visualization of DNA bands. The 25g packaging size is perfect for high-throughput laboratories and institutions that require large quantities of stain for DNA analysis. It is widely used in genetic research, PCR experiments, and DNA sequencing to detect DNA fragments in agarose gels, making it a crucial reagent in molecular biology and biochemistry labs.
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Medchemexpress LLC Propidium (iodide) | 25535-16-4 | 99.7% | 5 MG
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Propidium Iodide (PI) is a nuclear staining agent that stains DNA. It is an analogue of ethidine bromide, emitting red fluorescence when embedded in double-stranded DNA. PI cannot pass through living cell membranes but can pass through damaged cell membranes to stain the nucleus. It is commonly used in detecting apoptosis or necrosis and in flow cytometry analysis.
- Stains DNA
- Emits red fluorescence when embedded in double-stranded DNA
- Used in detection of apoptosis or necrosis
- Commonly used in flow cytometry analysis
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Apexbio Technology LLC Chelerythrine Chloride 3895-92-9 10mM (in 1mL DMSO)
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Chelerythrine Chloride (CAS 3895-92-9) is a benzophenanthridine alkaloid widely utilized as a selective antagonist of protein kinase C (PKC) with an IC50 of 0 66 M It acts as a high-specificity inhibitor by targeting the kinase regulatory domain serving as a competitive inhibitor with respect to phosphate receptors and a non-competitive inhibitor toward ATP Chelerythrine also inhibits Bcl-xL inducing apoptosis in mouse embryonic fibroblasts (MEFs) with an IC50 of 1 1 M It activates the JNK1 and p38 pathways via MEKK1 and MKK4 contributing to its pro-apoptotic effects In cellular assays chelerythrine reduces cell viability (MTT IC50 2 6 M) and in animal studies promotes apoptosis through reactive oxygen species generation Its applications extend to research on kinase activity apoptosis antimicrobial activity and anti-inflammatory processes
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Medchemexpress LLC ACT-1004-1239 | 2178049-58-4 | 98.81% | C27H28F2N6O3 | 25 MG
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ACT-1004-1239 is a potent, selective, and orally active CXCR7 antagonist with an IC50 value of 3.2 nM, developed for research purposes only. This compound promotes oligodendrocyte precursor cell differentiation and has shown promise in reducing disease severity in models of inflammatory demyelinating diseases.
- Potent and selective CXCR7 antagonist
- Orally active with an IC50 of 3.2 nM
- Promotes oligodendrocyte precursor cell (OPC) differentiation
- Increases plasma CXCL12 concentration in mice
- Reduces disease severity in MOG-induced experimental autoimmune encephalomyelitis (EAE) model
- Increases myelination in Cuprizone-induced demyelination model mice
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