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Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1

Medchemexpress LLC 5-amino-6-chloro-n-[(1-isobutylpiperidin-4-yl)methyl]-2-methylimidazo[1,2-a]pyridine-8-carboxamide | 519148-48-2 | 98.3% | 377.91 g/mol | C19H28ClN5O | 200 MG
SDP

CJ033466 is a research-grade selective 5-HT4 receptor partial agonist with a reported EC50 of 9 nM and demonstrated gastroprokinetic activity. It is supplied as a purified solid intended for in vitro and in vivo pharmacology research.

  • Selective 5-HT4 receptor partial agonist (EC50 9 nM).
  • Reported gastroprokinetic activity in preclinical studies.
  • High purity (98.29%), suitable for pharmacology research.
  • Molecular formula C19H28ClN5O; molecular weight 377.91 g/mol.
  • Soluble in DMSO (50 mg/mL) with ultrasonic/warming up to 80°C.
  • Storage: solid at 4°C; in solvent -80°C (6 months), -20°C (1 month).
  • Available in research quantities including 200 mg.

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2

Medchemexpress LLC Heptadecan-9-amine (9-aminoheptadecane) | 3241-20-1 | MFCD30742905 | 255.48 g/mol | C17H37N | 25 G
SDP

Heptadecan-9-amine (9-aminoheptadecane) is a primary C17 alkylamine used as an intermediate and reagent in organic synthesis and biochemical research. It is a colorless liquid with molecular formula C17H37N and molecular weight 255.48 g/mol.

  • Primary C17 alkylamine for use as a chemical building block.
  • Suitable for organic and medicinal chemistry applications.
  • Colorless liquid appearance, suitable for solution-phase handling.
  • CAS number 3241-20-1 for unambiguous identification.
  • Available in laboratory pack sizes, including 25 G.
  • Store at 4°C protected from light; in solvent, store at -80°C for long-term stability.

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3

Medchemexpress LLC Veliparib | 912444-00-9 | MFCD16661059 | 244.29 g/mol | C13H16N4O | 200 MG
SDP

Veliparib (ABT-888) is a small-molecule inhibitor of poly(ADP-ribose) polymerases used in research to probe DNA repair pathways and for chemosensitization studies. It is supplied as a solid for analytical and preclinical research and has documented storage recommendations for powder and solutions.

  • Potent PARP1 and PARP2 inhibition (Ki 5.2 nM and 2.9 nM).
  • Molecular formula C13H16N4O and molecular weight 244.29 g/mol.
  • Identified by CAS number 912444-00-9.
  • Supplied as a powder with recommended storage: -20°C (3 years) or 4°C (2 years).
  • Stable in solvent when stored at -80°C (1 year) or -20°C (6 months).

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4

Apexbio Technology LLC Ro 31-8220 125314-64-9 50mg
SDP

Ro 31-8220 (CAS 125314-64-9) is a potent and selective inhibitor of protein kinase C (PKC) targeting isoforms PKC- (IC50 5 nM) PKC- I (24 nM) PKC- II (14 nM) PKC- (27 nM) and PKC- (24 nM) PKC is a Ca2 and phospholipid-dependent serine/threonine kinase involved in signaling pathways regulating cell proliferation and malignancy Ro 31-8220 modulates downstream signaling by inducing c-Jun expression and activating JNK1 while inhibiting MKP-1 and c-Fos expression independent of PKC activity In immunological studies it suppresses IL-2 production (IC50 80 nM) T cell proliferation (IC50 350 nM) and CD25 expression indicating inhibition of both early and late T cell activation Ro 31-8220 is widely utilized in cellular and molecular studies to dissect PKC-dependent and independent signaling mechanisms

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5

Medchemexpress LLC Azido-PEG9-amine | 1207714-69-9 | 98.5% | 482.57 g/mol | C20H42N4O9 | 50 MG
SDP

Azido-PEG9-amine is a non-cleavable nine-unit polyethylene glycol (PEG) linker bearing an azide and a terminal amine. It is used for antibody-drug conjugate and PROTAC synthesis and enables bioconjugation via click chemistry (CuAAC and SPAAC).

  • Molecular formula: C20H42N4O9.
  • Molecular weight: 482.57 g/mol.
  • Cas number: 1207714-69-9.
  • Purity: 98.52%.
  • Available package sizes: 50 mg, 100 mg, 250 mg, 500 mg, 1 g.
  • Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
  • Compatible with copper-catalyzed azide-alkyne cycloaddition and strain-promoted alkyne-azide cycloaddition for bioconjugation.

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6

Medchemexpress LLC Cyclooctyne-o-amido-peg4-vc-pab-gly-gly-nh-o-co-exatecan | 2699066-62-9 | 97.3% | 1396.51 | C69H90FN11O19 | 1 MG
SDP

Cyclooctyne-O-amido-PEG4-VC-PAB-Gly-Gly-NH-O-CO-Exatecan is a cleavable drug-linker conjugate intended for antibody-drug conjugate (ADC) research, where Exatecan serves as the cytotoxic payload. Supplied as a solid for research use only, it is used in conjugation chemistry and ADC synthesis.

  • Molecular formula: C69H90FN11O19.
  • Molecular weight: 1396.51.
  • Purity: 97.3%.
  • Physical state: solid.
  • Cas number: 2699066-62-9.
  • Available sizes: 1 mg and 5 mg vials; larger quantities available by quotation.
  • Storage: 4°C under nitrogen; in solvent: -80°C (up to 6 months) or -20°C (up to 1 month), stored under nitrogen.
  • For research use only; not for human or veterinary use.

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