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Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.
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Dihydrexidine hydrochloride is a potent, selective full-efficacy D1/D5 dopamine receptor agonist used as a research reagent in pharmacology and neuroscience studies. The product is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) suitable for in vitro and preclinical applications.
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BAY-826 is a selective, potent small-molecule inhibitor of the TIE-2 kinase supplied for research use. It binds TIE-2 with high affinity (Kd ≈ 1.6 nM) and is provided as a 10 mM solution in DMSO (1 mL) or as solid quantities. Typical applications include biochemical kinase assays and cell-based studies of angiogenesis signaling pathways.
Selective TIE-2 inhibition with Kd ≈ 1.6 nM.
Available as 10 mM solution in DMSO (1 mL) and multiple solid sizes.
High purity suitable for research applications.
Molecular formula C26H19F5N6OS; molecular weight 558.53 g·mol⁻1.
Soluble in DMSO for convenient assay preparation.
Suitable for biochemical and cell-based assays targeting TIE-2 signaling.
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BAY-826 is a small-molecule chemical probe that selectively inhibits the receptor tyrosine kinase TIE-2 (TEK). It shows low-nanomolar biochemical potency and potent cellular activity, and is supplied for research use in solid and DMSO solution formats for preclinical mechanism-of-action and signaling studies.
Selective TIE-2 inhibition (Kd = 1.6 nM).
Potent cellular activity (EC50 = 1.3 nM for TIE-2 autophosphorylation in HUVECs).
Characterized kinase selectivity with limited off-target binding.
Available as solid (5-500 mg) and as 10 mM solution in DMSO.
Suitable for preclinical research applications and mechanistic studies.
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BAY-826 is a selective, potent small-molecule inhibitor of the TIE-2 (TEK) receptor tyrosine kinase used as a research chemical probe. It exhibits low-nanomolar binding (reported Kd ≈ 1.6 nM) and has been characterized in biochemical, cellular, and in vivo models. Supplied as a solid with high reported purity, it is intended for research use only.
Low-nanomolar potency against TIE-2 enabling sensitive biochemical assays.
High selectivity across kinases to reduce off-target activity.
Validated in cellular assays for target engagement.
Shown in vivo activity in preclinical models.
High reported purity suitable for pharmacology studies.
Soluble in DMSO for solution formulations.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
BAY-826 is a small-molecule chemical probe that selectively and potently inhibits the receptor tyrosine kinase TIE-2 (Kd ≈ 1.6 nM). It is supplied for research use only and has been characterized in preclinical studies. The compound has molecular formula C26H19F5N6OS and a molecular weight of 558.53 g/mol.
Selective, potent TIE-2 inhibition with low nanomolar affinity.
Characterized for in vitro and in vivo preclinical studies.
Supplied as a solid and available in multiple pack sizes, with DMSO solutions for convenience.
High chemical purity suitable for research applications.
Molecular weight 558.53 g/mol and formula C26H19F5N6OS.
Intended for research use only; not for clinical or human use.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More