Quinolines and derivatives
Apexbio Technology LLC Molnupiravir(Synonyms: EIDD-2801, MK-4482, Lagevrio, Molnupex, EIDD-1931-isopropyl ester, EIDD-2801 prodrug), 200mg, CAS: 2349386-89-4.
Molnupiravir (CAS 2349386-89-4) is an orally bioavailable nucleoside analog prodrug metabolized intracellularly into an active nucleoside triphosphate derivative Its antiviral effect occurs once incorporated by viral RNA-dependent RNA polymerase into newly synthesized viral RNA inducing an accumulation of mutations that disrupt viral genome fidelity and replication In research applications Molnupiravir is extensively employed for in vitro and in vivo studies investigating antiviral activities replication mechanisms and pharmacological responses especially against RNA viruses such as SARS-CoV-2 influenza virus and other coronaviruses
Medchemexpress LLC (S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one | 654059-21-9 | 99.8% | 266.34 g/mol | C14H22N2O3 | 100 MG
BAY 59-9435 (HSL-IN-2) is a potent, selective small-molecule inhibitor of hormone-sensitive lipase (HSL) with an IC50 of 0.023 μM. It exhibits cellular activity (28 nM in 3T3-L1 cells for inhibition of forskolin-stimulated lipolysis) and is supplied as a high-purity solid for research use, with recommended storage conditions to maintain stability.
- Potent and selective HSL inhibition (IC50 0.023 μM).
- Demonstrated cellular activity in adipocyte assays (28 nM).
- High purity suitable for biochemical and cellular studies.
- Stable as powder under recommended storage conditions.
- Soluble in DMSO for assay preparation.
Cayman Chemical allcis4 7 10 13 16Docosapenta
An ω-6 isomer of docosapentaenoic acid formed by the elongation and desaturation of arachidonic acid; diminished during fatty acid desaturase syndrome and increased in non-alcoholic steatohepatitis
Cayman Chemical allcis4 7 10 13 16Docosapenta
An ω-6 isomer of docosapentaenoic acid formed by the elongation and desaturation of arachidonic acid; diminished during fatty acid desaturase syndrome and increased in non-alcoholic steatohepatitis
Cayman Chemical allcis4 7 10 13 16Docosapenta
An ω-6 isomer of docosapentaenoic acid formed by the elongation and desaturation of arachidonic acid; diminished during fatty acid desaturase syndrome and increased in non-alcoholic steatohepatitis
Cayman Chemical allcis4 7 10 13 16Docosapenta
An ω-6 isomer of docosapentaenoic acid formed by the elongation and desaturation of arachidonic acid; diminished during fatty acid desaturase syndrome and increased in non-alcoholic steatohepatitis
Medchemexpress LLC Nitrendipine | 39562-70-4 | 99.7% | 200 MG
Nitrendipine (BAY-E-5009) is an orally active dihydropyridine calcium channel blocker, an analog of Nifedipine. It has been shown to induce apoptosis and possess antihypertensive effects. This compound can block alcohol and morphine withdrawal symptoms, reduce right ventricular hypertrophy, and mitigate pulmonary vascular changes induced by intermittent hypoxia. Furthermore, Nitrendipine exhibits anticancer effects on neuroblastoma cells.
- Orally active dihydropyridine calcium channel blocker
- Induces apoptosis
- Provides antihypertensive effects
- Blocks alcohol and morphine withdrawal symptoms
- Reduces right ventricular hypertrophy
- Mitigates pulmonary vascular changes induced by intermittent hypoxia
- Exhibits anticancer effects on neuroblastoma
- Inhibits Cav1.2 current
- Prevents behavioral signs of ethanol withdrawal
- Attenuates lipid peroxidation in the lung
Apexbio Technology LLC Tempo 2564-83-2 200mg
Tempo (CAS 2564-83-2) is a stable nitroxide radical widely employed in biomedical research for its redox-active properties It facilitates the dismutation of superoxide radicals thereby modulating mitochondrial reactive oxygen species (ROS) levels and influencing cellular oxidative stress responses Tempo also serves as an oxidation catalyst particularly in the transformation of primary alcohols to aldehydes Studies indicate that Tempo exerts both antioxidant and mutagenic effects inducing DNA strand breaks and displaying cytotoxic and mutagenic activities in in vitro models such as murine lymphoma cells It is utilized for investigating oxidative stress redox regulation and chemical mutagenesis
Apexbio Technology LLC Solanesol 13190-97-1 200mg
Solanesol is a lipophilic terpene alcohol derived from plants in the Solanaceae family characterized by anti-inflammatory neuroprotective and antimicrobial activity In vitro studies indicate solanesol regulates specific signaling pathways implicated in inflammatory responses and neurodegenerative processes possibly through modulation of enzyme activity and intracellular targets Experimental evidence demonstrates solanesol inhibits inflammation-associated enzymes with reported IC50 values typically ranging from low to mid micromolar concentrations depending on cell types and assay conditions This compound is utilized in biochemical research focused on elucidating molecular pathways involved in inflammation-mediated diseases and evaluating therapeutic potential as a neuroprotective agent