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Tetrahydroisoquinolines

Organic heterocyclic compounds that consist of an isoquinoline ring with no double bonds; contains a benzene ring fused to a six-membered ring with one nitrogen atom and five carbon atoms.
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Search Within Results
Keyword Search:
211 – 225 of 295 results
211

eMolecules​ 486427-17-2 | Medchem Express | CIQ | 5mg | 446269330 | HY-18699 | MFCD04411904 | 467.95 | C26H26ClNO5

Medchem Express | c(phg-isoDGR-(NMe)k) (TFA) | 1mg | 495799750 | HY-111413A | | 717.704 | C29H42F3N9O9

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eMolecules Building Block Tool<|a>

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212

Medchemexpress LLC HY-N0221 5mg Medchemexpress, Daurisoline CAS:70553-76-3 Purity:>98%
SDP

Medchemexpress, HY-N0221 5mg Daurisoline CAS:70553-76-3 Daurisoline is a hERG inhibitor and also an autophagy blocker. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

ENCOMPASS_PREFERRED
213

Medchemexpress LLC HY-112562 10mg Medchemexpress, GPR84 antagonist 8 CAS:1445846-30-9 Purity:>98%
SDP

Medchemexpress, HY-112562 10mg GPR84 antagonist 8 CAS:1445846-30-9 GPR84 antagonist 8 is a selective GPR84 antagonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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214

Medchemexpress LLC Nampt-IN-5 | 2380013-17-0 | >98.0% | 50 MG
SDP

Nampt-IN-5 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor that also inhibits CYP3A4 activity. It exhibits cellular IC50s of 0.7 nM and 3.9 nM against A2780 and COR-L23 cell lines, respectively, demonstrating antiproliferative effects. In vivo, it causes significant body weight loss in nude mice and shows favorable ADME data.

  • Potent NAMPT inhibitor
  • Inhibits CYP3A4 activity
  • Exhibits antiproliferative activity against A2780 and COR-L23 cell lines
  • Shows good ADME data in vitro
  • Induces significant body weight loss in nude mice in vivo

ENCOMPASS_PREFERRED
215

Sigma Aldrich Fine Chemicals Biosciences Salsolinol hydrobromide >=96% (HPLC) | 59709-57-8 | MFCD00012741 | 10MG

Salsolinol hydrobromide >=96% (HPLC) | Purity: >=96% (HPLC) | Mol Wt: 260.13 | 59709-57-8 | MFCD00012741 | 10MG

ENCOMPASS
216

Medchemexpress LLC Nampt-IN-3 | 2121591-52-2 | MFCD28053555 | 99.0% | 503.55 g/mol | C29H25N7O2 | 5 MG
SDP

Nampt-IN-3 is a high-purity, research-grade small molecule inhibitor that targets nicotinamide phosphoribosyltransferase (NAMPT) and histone deacetylases (HDAC). Supplied as a white to off-white solid, it exhibits low-nanomolar biochemical potency and documented cellular activity suitable for preclinical studies.

  • High purity (98.97%) solid suitable for research use.
  • Dual inhibitory activity against NAMPT and HDAC (IC50s ~31 nM and 55 nM).
  • Documented cytotoxicity in multiple cell lines (example IC50s in μM range).
  • Soluble in DMSO at high concentration; ultrasonic assistance recommended.
  • Stable as powder and in solution when stored per recommendations.
  • Available in small research pack sizes for early-stage studies.

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217

eMolecules​ 70553-76-3 | Medchem Express | Daurisoline | 5mg | 446274831 | HY-N0221 | MFCD00221740 | 610.751 | C37H42N2O6

Medchem Express | Daurisoline | 5mg | 446274831 | HY-N0221 | 70553-76-3 | MFCD00221740 | 610.751 | C37H42N2O6

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218

eMolecules​ 913358-93-7 | Medchem Express | Almorexant (hydrochloride) | 5mg | 446259253 | HY-10805A | MFCD27923874 | 549.03 | C29H32ClF3N2O3

Medchem Express | Almorexant (hydrochloride) | 5mg | 446259253 | HY-10805A | 913358-93-7 | MFCD27923874 | 549.030 | C29H32ClF3N2O3

ENCOMPASS_PREFERRED
219

eMolecules​ 1993226-94-0 | cis-5-(Boc-amino)-tetrahydro-pyran-2-carboxylic acid | J&W PharmLab LLC490.550 | C22H38N2O10 | 97.000 | CC(C)(C)OC(=O)N[C@H]1CC[C@H](OC1)C(O)=O.CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](OC1)C(O)=O | 1g | 599147672

cis-5-(Boc-amino)-tetrahydro-pyran-2-carboxylic acid | J&W PharmLab LLC | 1993226-94-0490.550 | C22H38N2O10 | 97.000 | CC(C)(C)OC(=O)N[C@H]1CC[C@H](OC1)C(O)=O.CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](OC1)C(O)=O | 1g | 599147672

ENCOMPASS_PREFERRED
220

Medchemexpress LLC Nampt-IN-3 | 2121591-52-2 | 99.0% | 503.55 | 1 ML
SDP

Nampt-IN-3 (Compound 35) is a small molecule inhibitor that simultaneously targets nicotinamide phosphoribosyltransferase (NAMPT) and HDAC, with IC50 values of 31 nM and 55 nM, respectively. It is effective in inducing cell apoptosis and autophagy, ultimately leading to cell death.

  • Simultaneously inhibits NAMPT and HDAC.
  • Induces cell apoptosis.
  • Induces autophagy.
  • Leads to cell death.
  • Demonstrates cytotoxicity in HCT-116, HepG2, and MDA-MB-231 cell lines.
  • Available in various quantities for research use.

ENCOMPASS_PREFERRED
221

Medchemexpress LLC Nampt-IN-3 | 2121591-52-2 | 99.0% | 503.55 | 100 MG
SDP

Nampt-IN-3 (Compound 35) simultaneously inhibits nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM, respectively. It effectively induces cell apoptosis and autophagy, leading to cell death.

  • Inhibits nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM.
  • Effectively induces cell apoptosis and autophagy.
  • Leads to cell death.
  • Demonstrates cytotoxicity in human HCT116 cells with an IC50 of 2.4 μM.
  • Demonstrates cytotoxicity in human HepG2 cells with an IC50 of 4.5 μM.
  • Demonstrates cytotoxicity in human MDA-MB-231 cells with an IC50 of 10 μM.

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222

eMolecules​ 1263377-98-5 | 6-Methoxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydrochloride | J & W PharmLab, LLC | MFCD18432556 | 243.690 | C11H14ClNO3 | 96.000 | Cl.COc1ccc2C(NCCc2c1)C(O)=O | 5g | 249981947

6-Methoxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydrochloride | J & W PharmLab, LLC | 1263377-98-5 | MFCD18432556 | 243.690 | C11H14ClNO3 | 96.000 | Cl.COc1ccc2C(NCCc2c1)C(O)=O | 5g | 249981947

ENCOMPASS_PREFERRED
223

eMolecules​ 3470-55-1 | 2-Amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one | MFCD11036256 | 250mg

Ambeed | (3-((3-Ethoxy-3-oxopropyl)carbamoyl)phenyl)boronic acid | 250mg | 716948067 | A648461 | 850567-28-1 | MFCD04115701 | 265.070 | C12H16BNO5

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>

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224

eMolecules​ 1922707-24-1 | METHYL 2-AMINO-2-(TETRAHYDROFURAN-3-YL)ACETATE HCL | MFCD25541920 | 1g

Ambeed | 7-Fluoro-1H-benzo[d][13]oxazine-24-dione | 1g | 525101754 | A184231 | 321-50-6 | MFCD03839826 | 181.122 | C8H4FNO3

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>

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225

Medchemexpress LLC Nampt-IN-5 | 2380013-17-0 | 98.0% | 100 MG
SDP

Nampt-IN-5 is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) and also inhibits CYP3A4 activity. It demonstrates significant antiproliferative activity, with cellular IC50s of 0.7 nM against A2780 cells and 3.9 nM against COR-L23 cells.

  • Potent NAMPT inhibitor
  • Inhibits CYP3A4 activity
  • Exhibits cellular IC50 of 0.7 nM against A2780 cells
  • Exhibits cellular IC50 of 3.9 nM against COR-L23 cells
  • Soluble in DMSO at 50 mg/mL
  • Stable as powder for 3 years at -20°C
  • Stable in solvent for 6 months at -80°C or 1 month at -20°C

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